Results 51 to 60 of about 3,923,906 (342)

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard, Hital Patel, Paula C. Vincent, Justine Kahn, Kira Bona, Thai Hoa Tran, Elisa M. Rodriguez, Kristopher Attwood, Kara M. Kelly   +8 more
wiley   +1 more source

Stability Indicating HPLC-ECD Method for the Analysis of Clarithromycin in Pharmaceutical Dosage Forms: Method Scaling versus Re-Validation

Scientia Pharmaceutica, 2019
An isocratic high-performance liquid chromatographic method using electrochemical detection (HPLC-ECD) for the quantitation of clarithromycin (CLA) was developed using Response Surface Methodology (RSM) based on a Central Composite Design (CCD).
Pedzisai A. Makoni, Mellisa T.R. Chikukwa, Sandile M.M. Khamanga, Roderick B. Walker   +3 more
doaj   +1 more source

Quantification of Nτ -Methylhistidine and Nπ-Methylhistidine in Chicken Plasma by Liquid Chromatography–Tandem Mass Spectrometry

The Journal of Poultry Science, 2023
The concentration of Nτ-methylhistidine in plasma provides an index of skeletal muscle protein breakdown. This study aimed to establish a quantitative method for measuring the concentrations of Nτ-methylhistidine and its isomer Nπ-methylhistidine in ...
Jun-ichi Shiraishi, Daichi Ijiri, Ayumi Katafuchi, Shozo Tomonaga, Saki Shimamoto, Hanwool Do, Shinya Ishihara, Akira Ohtsuka   +7 more
doaj   +1 more source

A GCV based Arnoldi-Tikhonov regularization method

, 2013
For the solution of linear discrete ill-posed problems, in this paper we consider the Arnoldi-Tikhonov method coupled with the Generalized Cross Validation for the computation of the regularization parameter at each iteration.
Novati, Paolo, Russo, Maria Rosaria
core   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

Multicenter Analytical Validation of Aβ40 Immunoassays

Frontiers in Neurology, 2017
BackgroundBefore implementation in clinical practice, biomarker assays need to be thoroughly analytically validated. There is currently a strong interest in implementation of the ratio of amyloid-β peptide 1-42 and 1-40 (Aβ42/Aβ40) in clinical routine ...
Linda J. C. van Waalwijk van Doorn, Linda J. C. van Waalwijk van Doorn, Luka Kulic, Marleen J. A. Koel-Simmelink, H. Bea Kuiperij, H. Bea Kuiperij, Alexandra A. M. Versleijen, Hanne Struyfs, Harry A. M. Twaalfhoven, Anthony Fourier, Sebastiaan Engelborghs, Sebastiaan Engelborghs, Armand Perret-Liaudet, Sylvain Lehmann, Marcel M. Verbeek, Marcel M. Verbeek, Eugeen J. M. Vanmechelen, Charlotte E. Teunissen   +17 more
doaj   +1 more source

FMS-TTP-SPE Ön Hazırlık Sistemi Kullanılarak Polisiklik Aromatik Hidrokarbonların Analizi için Yöntem Geliştirilmesi: Yöntemin Isparta İli Gölcük Gölünden Alınan Su Numunelerine Uygulanması

Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2023
Polisiklik Aromatik Hidrokarbon (PAH) bileşiklerinin kanserojen etkilerinin yüksek olduğu bilinmektedir. PAH’ların sulardaki çözünürlük değerlerinin düşük (nanogram/litre) olması nedeni ile PAH tayini ön hazırlık işlemlerinin doğru yapılması ve farklı ...
Murat Kılıç, Ömer Dilek
doaj   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

UV derivative spectrophotometric method for determination of estradiol valerate in tablets

Química Nova, 2010
A derivative UV spectrophotometric method for determination of estradiol valerate in tablets was validated. The parameters specificity, linearity, precision, accuracy, limit of detection and limit of quantitation were studied according to validation ...
Andreas S. L. Mendez, Lislaine Deconto, Cássia V. Garcia   +2 more
doaj   +1 more source