Results 171 to 180 of about 267,001 (338)

Reply to: Methotrexate toxicity and glucarpidase: A call for dose optimization. Koppen A, et al. Br J Clin Pharmacol. 2025;91(5):1289‐1292 doi:10.1002/bcp.70044

British Journal of Clinical Pharmacology, EarlyView.
Carmelo Rizzari, Stefan Schwartz
wiley   +1 more source

Folinic Acid Prophylaxis and Dose Adjustments Enable Safe Treatment with Pemetrexed in Patients with Renal Impairment

Clinical Pharmacology &Therapeutics, EarlyView.
Pemetrexed is a cornerstone in chemo(immunotherapy) of non‐small cell lung cancer and mesothelioma; however, it is contraindicated in patients with renal impairment due to severe toxicity concerns. Therefore, a large proportion of patients is withheld from effective chemo(immunotherapy).
Nikki de Rouw, Leila‐Sophie Otten, Mart P. Kicken, Berber Piet, Bonne Biesma, Bianca van Veggel, Christi M.J. Steendam, Ben van den Borne, Lizza E.L. Hendriks, Sander Croes, Anne‐Marie C. Dingemans, Daphne W. Dumoulin, Ron H.J. Mathijssen, Jacobus A. Burgers, Alwin D.R. Huitema, Hieronymus J. Derijks, Maarten J. Deenen, Michel M. van den Heuvel, Rob ter Heine   +18 more
wiley   +1 more source

Methotrexate-induced sudden fatal pulmonary reaction [PDF]

, 1977
André D. Lascari, Alfonso J. Strano, Warren W. Johnson, James Collins   +3 more
openalex   +1 more source

Surface Wipe Sampling of Hazardous Medicinal Products: A European Interlaboratory Comparison Study

Drug Testing and Analysis, EarlyView.
This study aimed to conduct an interlaboratory comparison (ILC) program to evaluate the performance of European laboratories in detecting hazardous medicinal products (HMPs) from surface wipe samples, using their own sampling and analytical methods.
Roland B. van den Berg, Ewelina Korczowska, Mónica S. F. Santos, Maria Francisca Portilha‐Cunha, Ana R. L. Ribeiro, Lucie Bláhová, Luděk Bláha, Claudia Vom Eyser, Jochen Tuerk, Richard C. J. M. van Rossen, Erik B. Wilms, Mirjam Crul   +11 more
wiley   +1 more source

Loss of the epithelial transcription factor grhl3 leads to variably penetrant developmental phenotypes in zebrafish

Developmental Dynamics, EarlyView.
Abstract Background Environmental influence is critical for embryogenesis but is significantly under‐appreciated under lab conditions, which are not typically designed to robustly test environmental variability. Here, we report environmental effects on the developmental phenotype of zebrafish lacking the transcription factor Grainyhead‐like 3 (grhl3 ...
Nishanthi Mathiyalagan, Travis K. Johnson, Zachary Di Pastena, Jarrad N. Fuller, Lee B. Miles, Sebastian Dworkin   +5 more
wiley   +1 more source

Two Consecutive Days of Low-Dose Methotrexate Toxicity: A Diagnostic Challenge. [PDF]

Cureus
Harimohan H, Huynh Q, Yasonova M, Moosavi L, Khamlong M, Garcia Pacheco I.   +5 more
europepmc   +1 more source

Think highly of immunoglobulin G4‐related chronic rhinosinusitis as a clinical entity in immunoglobulin G4‐related disease

Eye &ENT Research, EarlyView.
Abstract IgG4‐related chronic rhinosinusitis (IgG4‐related CRS) is gaining recognition among various specialized physicians. As a systemic disease involving multiple organs, IgG4‐related CRS is still not widely recognized as an independent clinical entity. Given the complexity of diagnosing autoimmune‐related multisystem diseases, early recognition and
Lianqi Wan, Luo Zhang, Yingshi Piao, Yuan Zhang   +3 more
wiley   +1 more source

Long-Term Remission following Methotrexate Therapy in a Case of Hand-Schuller-Christian Disease

, 1965
K.A. Newton, Ian Anderson
openalex   +1 more source

Low dose chemotherapy of metastatic breast cancer with cyclophosphamide, adriamycin, methotrexate, 5-fluorouracil (CAMF) versus sequential cyclophosphamide, methotrexate, 5-fluorouracil (CMF) and adriamycin [PDF]

, 1979
Richard H. Creech, Robert B. Catalano, David T. Harris, Paul F. Engstrom, Paul J. Grotzinger   +4 more
openalex   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source