Results 231 to 240 of about 283,343 (354)

Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases

ChemistryEurope, EarlyView.
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang, Jinxia Wang, Guang‐Zhi Jin, István Bányai, Dzmitry Shcharbin, Ivan Stoikov, Mingwu Shen, Xiangyang Shi   +7 more
wiley   +1 more source

Severe Hepatitis in a Patient With Undifferentiated Connective Tissue Disease: Diagnostic Uncertainty Between Methotrexate Toxicity and Autoimmune Liver Involvement. [PDF]

Cureus
Reyad B.
europepmc   +1 more source

Non‐Syndromic Tumefactive Demyelinating Lesions in the Pediatric Population: Four Case Reports and Review of the Literature

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Tumefactive demyelinating lesions (TDLs) are large lesions (> 2 cm) seen in demyelinating syndromes such as multiple sclerosis, myelin oligodendrocyte glycoprotein antibody‐associated disorder, and neuromyelitis optica spectrum disorder. They rarely occur in children and most often have a monophasic course.
Elizabeth C. Ballinger, Hannah F. Todd, Jonathan M. Yarimi, Timothy E. Lotze, Nikita M. Shukla, Kristen S. Fisher, Alexander J. Sandweiss   +6 more
wiley   +1 more source

Tissue-type Differences in Focused Ultrasound and Microbubble-mediated Drug Delivery to the Brain Exist at Vessel Level. [PDF]

Theranostics
De Maio A, Lin FH, Stefanovic B, O'Reilly MA.   +3 more
europepmc   +1 more source

Porous Organic Frameworks‐Based Nanomaterials in Colorectal Cancer Therapy: From Drug Delivery to Personalized Nano‐Vaccine

Cancer Nexus, EarlyView.
ABSTRACT Colorectal cancer (CRC), as the second most common cause of cancer death worldwide, has seen a significant increase in its incidence rate in recent years. However, the current major clinical treatment methods, such as surgery, chemotherapy and radiotherapy, still have certain limitations and are difficult to achieve a complete cure.
Xiaoyu Song, Hao Zhang, Yinghui Wang, Chao Luo   +3 more
wiley   +1 more source

Induction chemotherapy with methotrexate, nimustine, and procarbazine for primary CNS lymphoma in the elderly: a retrospective evaluation of safety and efficacy. [PDF]

J Neurooncol
Umezawa Y, Yamamoto M, Tanaka K, Yoshifuji K, Akiyama H, Nogami A, Nagao T, Mori T.   +7 more
europepmc   +1 more source

ONS Methotrexate Mortality Data

, 2019
Brian MacKenna, Richard Croker, Helen J Curtis, Alex Walker, Ben Goldacre   +4 more
openalex   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Necrotizing Granulomas and Lytic Bone Lesions: Unmasking a Rare Presentation of Osseous Sarcoidosis in the Absence of Pulmonary Disease. [PDF]

ACR Open Rheumatol
Harata M, Coffey C.
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source