Results 61 to 70 of about 166,279 (314)

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Liver Elastography for the Detection of Methotrexate-Induced Liver Injury: A Retrospective Study [PDF]

Background: Liver biopsy, the gold standard for monitoring of methotrexate-induced liver injury, is associated with significant morbidity and mortality.
Maya Mahmoud, Tim Brotherton, Kamran Qureshi, Sam Burton   +3 more
core   +1 more source

Methotrexate in Rheumatoid Arthritis [PDF]

, 1988
Over the past few years 'low dose pulse' methotrexate has gained increasing popularity as an effective treatment for refractory rheumatoid arthritis. Methotrexate has been shown to be better than placebo in controlled clinical trials.
Brooks, P. M.
core   +1 more source

National trends in treatments for ectopic pregnancy in Japan from 2010 to 2020: a retrospective observational study

Journal of Obstetrics and Gynaecology
Background Ectopic pregnancy (EP) can be treated surgically or nonsurgically. In many countries, methotrexate is frequently used as a first-line medical treatment, and its effect is similar to that of surgery in selected patients. We aimed to investigate
Risa Ishida, Hiroyuki Ohbe, Gentaro Izumi, Daisuke Shigemi, Hiroki Matsui, Kaori Koga, Hideo Yasunaga, Yutaka Osuga   +7 more
doaj   +1 more source

Potential contributors to low dose methotrexate toxicity in a patient with rheumatoid arthritis and pernicious anemia: case report

BMC Rheumatology, 2021
Background Low dose methotrexate toxicity rarely occurs, but may present with severe complications, such as pancytopenia, hepatotoxicity, mucositis, and pneumonitis.
Miguel A. Jara-Palacios, William Chun, Nomi L. Traub   +2 more
doaj   +1 more source

Methotrexate

, 2016
Methotrexate is an analogue of folates (Fig. 1) and is a cytotoxic drug used in the treatment of several malignancies. At low doses, methotrexate is a member of the drug group slow-acting antirheumatic drugs (SAARDs).
Pile, Kevin (R17082), Garry G. Graham, Kevin D. Pile, Graham, Garry G.   +3 more
core   +1 more source

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

Arthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper, Rachel Black, Joanna Tieu, Winnie Chen, Matthew Parker, Catherine Hill, Natasha Nassar, Mandana Nikpour   +7 more
wiley   +1 more source

Evaluation of the efficacy and safety of combined treatment with methotrexate and a broadband medium-wave phototherapy for psoriasis patients

Vestnik Dermatologii i Venerologii, 2017
Goal. To evaluate the efficacy and safety of combined treatment with methotrexate and a broadband medium-wave phototherapy for psoriasis patients. Materials and methods. As many as 365 psoriasis patients underwent examination and treatment.
D. V. Grigoriyev, V. V. Vladimirov
doaj   +1 more source

The Study of Results of Liver Biopsy in Psoriatic Patients Which Treated by Methotrexate

پزشکی بالینی ابن سینا, 1996
Objective: To assess Methotrexate-related side effects on the liver. Patients & methods: 45 liver biopsies were examined in dermatology ward of Loghman-e-Hakim Hospital in 1986-91.27 liver biopsies were examined after treatment with Methotrexate and ...
Shora Manighalam, Parviz Toosi, Shahram Tahriri   +2 more
doaj  

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source