Results 51 to 60 of about 137,213 (265)

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

Arthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper, Rachel Black, Joanna Tieu, Winnie Chen, Matthew Parker, Catherine Hill, Natasha Nassar, Mandana Nikpour   +7 more
wiley   +1 more source

Methotrexate-induced intestinal mucositis delays gastric emptying and gastrointestinal transit of liquids in awake rats

Arquivos de Gastroenterologia, 2011
CONTEXT: Methotrexate and other anticancer agents can induce intestinal mucositis, which is one of the most common limiting factor that prevent further dose escalation of the methotrexate. OBJECTIVES: To evaluate the gastric emptying and gastrointestinal
Pedro M. G. Soares, Lorena O. Lopes, José Maurício S. C. Mota, José Nelson Belarmino-Filho, Ronaldo A. Ribeiro, Marcellus Henrique L. P. de Souza   +5 more
doaj   +1 more source

The Study of Results of Liver Biopsy in Psoriatic Patients Which Treated by Methotrexate

پزشکی بالینی ابن سینا, 1996
Objective: To assess Methotrexate-related side effects on the liver. Patients & methods: 45 liver biopsies were examined in dermatology ward of Loghman-e-Hakim Hospital in 1986-91.27 liver biopsies were examined after treatment with Methotrexate and ...
Shora Manighalam, Parviz Toosi, Shahram Tahriri   +2 more
doaj  

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Methotrexate Is Associated With Reduced Cardiovascular Risk in U.S. Veterans With Rheumatoid Arthritis Independent of Disease Activity Modification

Graduate Medical Education Research Journal, 2020
Mentor: Bryant R. England Program: Internal Medicine, Division of Rheumatology Type: Original Research Background: Rheumatoid arthritis (RA) patients are at increased risk of cardiovascular disease (CVD). Methotrexate, a mainstay in RA treatment, appears
Tate Johnson, Joshua Baker, Punyasha Roul, Harlan Sayles, Grant W. Cannon, Brian Sauer, Ted Mikuls, Bryant England   +7 more
doaj   +1 more source

Analysis of Drug Metabolizing Gene Panel in Osteosarcoma Patients Identifies Association Between Variants in SULT1E1, CYP2B6 and CYP4F8 and Methotrexate Levels and Toxicities

Frontiers in Pharmacology, 2020
High-dose methotrexate is a cornerstone agent in the chemotherapeutic treatment of patients with osteosarcoma. However, patients often develop methotrexate-induced toxicities.
Evelien G. E. Hurkmans, Marije J. Klumpers, Sita H. Vermeulen, Melanie M. Hagleitner, Uta Flucke, H. W. Bart Schreuder, Hans Gelderblom, Johannes Bras, Henk-Jan Guchelaar, Marieke J. H. Coenen, D. Maroeska W. M. te Loo   +10 more
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Mucocutaneous Disease Activity and Damage Accrual in Systemic Lupus Erythematosus: Analyses From the Asia‐Pacific Lupus Collaboration Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective This research article aims to describe the prevalence, associations, and health‐related quality of life (HRQoL) impact of mucocutaneous features of systemic lupus erythematosus (SLE). Methods Data from the Asia‐Pacific Lupus Collaboration cohort were analyzed (2013–2021).
Amanda M. Saracino, Yanjie Hao, Dylan Hansen, Yi‐Hsing Chen, Alberta Hoi, Vera Golder, Jiacai Cho, Aisha Lateef, Worawit Louthrenoo, Laniyati Hamijoyo, Shue Fen Luo, Yeong‐Jian Jan Wu, Sandra Navarra, Leonid Zamora, Chak Sing Lau, Shirley Chan, Zhanguo Li, Hai‐hong Yao, Sargunan Sockalingam, B. M. D. B. Basnayake, Yasuhiro Katsumata, Masayoshi Harigai, Zhuoli Zhang, Jun Kikuchi, Yuko Kaneko, Tsutomu Takeuchi, Madelynn Chan, Sang‐Cheol Bae, Fiona Goldblatt, Sean O'Neill, Geraldine Hassett, Kristine Ng, Nicola Tugnet, Mark Sapsford, Yih Jia Poh, Michael Tee, Cherica Tee, Naoaki Ohkubo, Yoshiya Tanaka, Rangi Kandane‐Rathnayake, Eric Morand, Shereen Oon, Mandana Nikpour   +42 more
wiley   +1 more source

Methotrexate Crystals on Electron Microscopy of Kidney Biopsy for Acute Kidney Injury

Kidney Medicine
Acute kidney injury secondary to methotrexate therapy for hematologic malignancies is relatively uncommon. Methotrexate crystals in these cases are rarely seen on kidney biopsy, and in particular, their appearance in tissue prepared for transmission ...
Diana Fang, MD, Noah Poznanski, MD, Lois J. Arend, MD, PhD   +2 more
doaj   +1 more source

Biologic therapy with anti-TNFa in rheumathoid atrhritis

Reumatismo, 2011
Objective: To evaluate the efficacy, the tolerability, and treatment survival of the association of anti-TNFa (Infliximab, Etanercept, Adalimumab) plus Methotrexate vs Methotrexate as monotherapy in patients with reumathoid arthritis (RA).
G. Ferraccioli
doaj   +1 more source