Results 11 to 20 of about 2,832 (233)

Methoxsalen inhibited the acquisition of nicotine self-administration: attenuation by cotinine replacement in rats [PDF]

bioRxiv, 2023
Cigarette smoking remains the leading preventable cause of disease and death. Nicotine is the primary reinforcing ingredient in cigarettes sustaining addiction.
Zheng‐Ming Ding, Elizabeth Neslund, Dongxiao Sun, Xiao-Ying Tan   +3 more
openalex   +2 more sources

Methoxsalen Inhibits the Acquisition of Nicotine Self-Administration: Attenuation by Cotinine Replacement in Male Rats. [PDF]

Nicotine Tob Res
INTRODUCTION Cigarette smoking remains the leading preventable cause of disease and death. Nicotine is the primary reinforcing ingredient in cigarettes sustaining addiction.
Ding ZM, Neslund EM, Sun D, Tan X.
europepmc   +2 more sources

Exploring the mechanism of Liuwei Dihuang formula for promoting melanin synthesis in juvenile zebrafish based on network pharmacology and molecular docking [PDF]

Heliyon, 2023
Background: Vitiligo stands as a challenging skin disorder with limited treatment options available. LiuWei DiHuang formula (LDF), a renowned Traditional Chinese medicine, has exhibited promising results in treating vitiligo over an extended period ...
Dandan Wang, Yan Yang, Gulijiayina Hengerjia, Yan Deng   +3 more
doaj   +2 more sources

The Effect of Methoxsalen Dose on Ultraviolet-A-Induced Erythema [PDF]

Journal of Investigative Dermatology, 2001
There is considerable interindividual variation in bioavailability of Methoxsalen (8-methoxypsoralen) after ingestion of the standard dose used in photochemotherapy (psoralen plus ultraviolet A). A dose change may be used to alter the degree of photosensitivity, although there is limited information on the effect of 8-methoxypsoralen dose alterations ...
Ibbotson, Sally H., Dawe, Robert S., Farr, Peter M.   +2 more
openaire   +5 more sources

Single-Cell Analysis Integrated With Machine Learning Elucidates the Mechanisms of Nucleus Pulposus Cells Apoptosis in Intervertebral Disc Degeneration and Therapeutic Interventions. [PDF]

JOR Spine
IVDD has various NPC subgroups, including HT‐CLNP, fibrous NPC, sticky NPC, regulatory NPC, and steady‐state NPC. Furthermore, numerous immune cell infiltrates, particularly monocytes and macrophages, play a crucial role in the evolution of IVDD. Parthenogenesis' key components are Osthole, Columbianadin, and Bergapten, which absorb IVDD by managing ...
Song C, Wu X, Chen C, Shen B, Mei Y, Yan Q, Jiang F, Chen F, Liu F.   +8 more
europepmc   +2 more sources

Dehydrocostus Lactone Inhibits Microglia‐Mediated Neuroinflammation by Targeting CYP2A6 to Improve Ischemic Brain Injury [PDF]

CNS Neurosci Ther
Dehydrocostus lactone (DHC) inhibits microglia‐mediated neuroinflammation by targeting CYP2A6, reducing the release of pro‐inflammatory factors and improving nerve function impairment, thereby alleviating ischemic brain injury. ABSTRACT Background Neuroinflammation is an important factor in ischemic stroke.
Shu X, Zou X, Zhang J, Fang X, Wang X, Wu H, He X, Sha D.   +7 more
europepmc   +2 more sources

Group I pharmaceuticals of IARC and associated cancer risks: systematic review and meta-analysis [PDF]

Scientific Reports
We aimed to summarize the cancer risk among patients with indication of group I pharmaceuticals as stated in monographs presented by the International Agency for Research on Cancer working groups.
Woojin Lim, Sungji Moon, Na Rae Lee, Ho Gyun Shin, Su-Yeon Yu, Jung Eun Lee, Inah Kim, Kwang-Pil Ko, Sue K. Park   +8 more
doaj   +2 more sources

Extracorporeal photopheresis (ECP) in the treatment of chronic lung allograft dysfunction (CLAD): a prospective, multicentre, open-label, randomised controlled trial studying the addition of ECP to standard care in the treatment of bilateral lung transplant patients with CLAD (E-CLAD UK) [PDF]

BMJ Open Respiratory Research
Background Long-term survival after lung transplantation is limited compared with other organ transplants. The main cause is development of progressive immune-mediated damage to the lung allograft.
Martin Carby, Jasvir Parmar, Andrew Bryant, Thomas Chadwick, Luke Vale, Catherine Exley, Andrew J Fisher, Helen Hancock, Richard Thompson, Joanne Lally, Andrew R Gennery, Michelle Bardgett, Siân Russell, Michael White, James MS Wason, Nicola Goudie, Anneka Kershaw, Julia Phillipson, Alex Bevin-Nicholls, Hesther Smith, Laura Frisby, Rebecca Errington, Karthik Santhanakrishnan   +22 more
doaj   +2 more sources

Comparative Study of Efficacy and Safety of Coded Unani Formulations–UNIM-001+UNIM-003 with Methoxsalen in Cases of Bars (Vitiligo)

Journal of Advanced Research in Ayurveda Yoga Unani Sidhha & Homeopathy, 2020
Background: Vitiligo is a common acquired disorder of skin depigmentation in varying patterns, varying from small maculae’s with scalloping borders to near total depigmentation of body.
Parvez Khan
openalex   +3 more sources

Time-dependent change of T cell receptor clonality: From large plaque parapsoriasis to early mycosis fungoides. [PDF]

Skin Res Technol
Skin Research and Technology, Volume 30, Issue 8, August 2024.
Itoh M, Asahina A, Nobeyama Y.
europepmc   +2 more sources