Results 11 to 20 of about 2,112 (168)
Nb‐UVB and PUVA therapy in treating early stages of Mycosis Fungoides: A single‐center cross‐sectional study [PDF]
Photodermatology, Photoimmunology &Photomedicine, Volume 39, Issue 5, Page 435-440, September 2023., 2023 IntroductionMycosis fungoides (MF) and Sezary Syndrome are the most common forms of cutaneous T-cell lymphoma. Early-stage MF is known to have an indolent behavior, and the EORTC guidelines recommend treating patients with skin-directed therapies, such ...Bardazzi, Federico, Baruffaldi, Gregorio, Hrvatin Stancic, Bor, Mussi, Martina, Pileri, Alessandro, Piraccini, Bianca Maria, Zengarini, Corrado +6 morecore +2 more sourcesEffects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice [PDF]
, 2014 Metabolism of nicotine to inactive cotinine by hepatic enzyme CYP2A6 is the principal pathway by which active nicotine is removed from circulation. We therefore hypothesized that inhibition of mouse CYP2A5, the ortolog of human CYP2A6, by methoxsalen (8 ...Bagdas, Deniz, Damaj, M. Imad, Muldoon, Pretal P., Tyndale, Rachel F., Zhu, Andy Z.X. +4 morecore +3 more sourcesRandomized controlled study of ECP with methoxsalen as first-line treatment of patients with moderate to severe cGVHD
Blood Advances, 2019 : The investigation of extracorporeal photopheresis (ECP) plus standard of care (SoC) (SoC+ECP) in chronic graft-versus-host disease (cGVHD) within prospective, randomized clinical studies is limited, despite its frequent clinical use. This phase 1/pilot Madan Jagasia, Christof Scheid, Gérard Socié, Francis Ayuketang Ayuk, Johanna Tischer, Michele L. Donato, Árpád Bátai, Heidi Chen, Sheau-Chiann Chen, Thomas Chin, Henri Boodée, Ghaith Mitri, Hildegard T. Greinix +12 moredoaj +2 more sourcesCatalytic Synthesis of β‐(Hetero)arylethylamines: Modern Strategies and Advances
Angewandte Chemie, Volume 135, Issue 41, October 9, 2023., 2023 This review provides a comprehensive overview of the recent progresses made in the catalytic synthesis of β‐(hetero)arylethylamines, which have become widespread scaffolds in drug discovery. During the past decade, this field of research has expanded tremendously thanks to the development of enabling technologies such as C−H activation, photocatalysis, Valentyn Pozhydaiev, Cyprien Muller, Joseph Moran, David Lebœuf +3 morewiley +2 more sourcesPentafluorocyclopropanation of (Hetero)arenes Using Sulfonium Salts: Applications in Late‐Stage Functionalization
Angewandte Chemie, Volume 135, Issue 35, August 28, 2023., 2023 An unprecedented sulfonium salt is presented, which under mild photochemical conditions, is able to transfer pentafluorocyclo‐propenyl groups (C3F5−) at unfunctionalized positions of a number of (hetero)arenes. The reaction is compatible with a variety of functional groups, rendering this method a practical tool for future drug optimization campaigns ...Zeyu Feng, Lucas Riemann, Zichen Guo, David Herrero, Martin Simon, Christopher Golz, Ricardo A. Mata, Manuel Alcarazo +7 morewiley +2 more sourcesExtracorporeal photopheresis induces NETosis in neutrophils derived from patients with chronic graft‐vs‐host disease
Journal of Clinical Apheresis, Volume 38, Issue 5, Page 615-621, October 2023., 2023 Abstract Introduction
Extracorporeal photopheresis (ECP) is considered an effective treatment for patients with chronic graft vs host disease (cGVHD) and demonstrates efficacy in ameliorating GVHD. The mechanism by which ECP acts against cGVHD is not fully understood.Idan Goldberg, Galit Granot, Alona Telerman, Shirly Partouche, Tzippy Shochat, Erez Halperin, Anat Gafter‐Gvili, Liat Shargian, Moshe Yeshurun, Pia Raanani, Ofir Wolach, Vered Yahalom +11 morewiley +1 more sourceNew Chitosan Polymer Scaffold Schiff Bases as Potential Cytotoxic Activity: Synthesis, Molecular Docking, and Physiochemical Characterization
Frontiers in Chemistry, 2022 In this work, we synthesize the sulfonated Schiff bases of the chitosan derivatives 2a-2j without the use of a catalyst in two moderately straightforward steps with good yield within a short reaction time.Ponnusamy Packialakshmi, Perumal Gobinath, Daoud Ali, Saud Alarifi, Raman Gurusamy, Akbar Idhayadhulla, Radhakrishnan Surendrakumar +6 moredoaj +1 more sourceThe Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
British Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.Stephen P. H. Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Maria Pia Abbracchio, George Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria Blaho, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Geoffrey Burnstock, Girolamo Caló, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Deron Herr, Morley D. Hollenberg, Nicholas D. Holliday, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Kenneth A. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Tobias Langenhan, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Xaria X. Li, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet Maguire, Davide Malfacini, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Philippe Rondard, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Khuraijam Dhanachandra Singh, Craig M. Smith, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Chengcan Yao, Richard D. Ye +165 morewiley +1 more source