Results 11 to 20 of about 2,112 (168)

Nb‐UVB and PUVA therapy in treating early stages of Mycosis Fungoides: A single‐center cross‐sectional study [PDF]

open access: yesPhotodermatology, Photoimmunology &Photomedicine, Volume 39, Issue 5, Page 435-440, September 2023., 2023
IntroductionMycosis fungoides (MF) and Sezary Syndrome are the most common forms of cutaneous T-cell lymphoma. Early-stage MF is known to have an indolent behavior, and the EORTC guidelines recommend treating patients with skin-directed therapies, such ...
Bardazzi, Federico   +6 more
core   +2 more sources

Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice [PDF]

open access: green, 2014
Metabolism of nicotine to inactive cotinine by hepatic enzyme CYP2A6 is the principal pathway by which active nicotine is removed from circulation. We therefore hypothesized that inhibition of mouse CYP2A5, the ortolog of human CYP2A6, by methoxsalen (8 ...
Bagdas, Deniz   +4 more
core   +3 more sources

Randomized controlled study of ECP with methoxsalen as first-line treatment of patients with moderate to severe cGVHD

open access: goldBlood Advances, 2019
: The investigation of extracorporeal photopheresis (ECP) plus standard of care (SoC) (SoC+ECP) in chronic graft-versus-host disease (cGVHD) within prospective, randomized clinical studies is limited, despite its frequent clinical use. This phase 1/pilot
Madan Jagasia   +12 more
doaj   +2 more sources

Bullous Eruption Following Methoxsalen Treatment in a Pediatric Patient with Vitiligo Vulgaris

open access: diamondIndian Journal of Paediatric Dermatology
Shekhar Neema   +3 more
doaj   +2 more sources

Time-dependent change of T cell receptor clonality: From large plaque parapsoriasis to early mycosis fungoides. [PDF]

open access: yesSkin Res Technol
Skin Research and Technology, Volume 30, Issue 8, August 2024.
Itoh M, Asahina A, Nobeyama Y.
europepmc   +2 more sources

Catalytic Synthesis of β‐(Hetero)arylethylamines: Modern Strategies and Advances

open access: yesAngewandte Chemie, Volume 135, Issue 41, October 9, 2023., 2023
This review provides a comprehensive overview of the recent progresses made in the catalytic synthesis of β‐(hetero)arylethylamines, which have become widespread scaffolds in drug discovery. During the past decade, this field of research has expanded tremendously thanks to the development of enabling technologies such as C−H activation, photocatalysis,
Valentyn Pozhydaiev   +3 more
wiley   +2 more sources

Pentafluorocyclopropanation of (Hetero)arenes Using Sulfonium Salts: Applications in Late‐Stage Functionalization

open access: yesAngewandte Chemie, Volume 135, Issue 35, August 28, 2023., 2023
An unprecedented sulfonium salt is presented, which under mild photochemical conditions, is able to transfer pentafluorocyclo‐propenyl groups (C3F5−) at unfunctionalized positions of a number of (hetero)arenes. The reaction is compatible with a variety of functional groups, rendering this method a practical tool for future drug optimization campaigns ...
Zeyu Feng   +7 more
wiley   +2 more sources

Extracorporeal photopheresis induces NETosis in neutrophils derived from patients with chronic graft‐vs‐host disease

open access: yesJournal of Clinical Apheresis, Volume 38, Issue 5, Page 615-621, October 2023., 2023
Abstract Introduction Extracorporeal photopheresis (ECP) is considered an effective treatment for patients with chronic graft vs host disease (cGVHD) and demonstrates efficacy in ameliorating GVHD. The mechanism by which ECP acts against cGVHD is not fully understood.
Idan Goldberg   +11 more
wiley   +1 more source

New Chitosan Polymer Scaffold Schiff Bases as Potential Cytotoxic Activity: Synthesis, Molecular Docking, and Physiochemical Characterization

open access: yesFrontiers in Chemistry, 2022
In this work, we synthesize the sulfonated Schiff bases of the chitosan derivatives 2a-2j without the use of a catalyst in two moderately straightforward steps with good yield within a short reaction time.
Ponnusamy Packialakshmi   +6 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander   +165 more
wiley   +1 more source

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