Results 11 to 20 of about 1,920 (175)

Methoxsalen-induced macular toxicity

open access: diamondIndian Journal of Ophthalmology, 2017
Psoralen compounds such as methoxsalen are photosensitizer agents used in conjunction with ultraviolet A (UVA) radiation exposure as photochemotherapy (Psoralens and ultraviolet-A therapy [PUVA therapy]) for certain epidermal skin disorders such as ...
Aditya Maitray, Pukhraj Rishi
doaj   +5 more sources

Clinical and dermoscopic assessment of the efficacy of topical trichloroacetic acid 70% versus methoxsalen 0.2% paint in stable acral vitiligo [PDF]

open access: yesScientific Reports
Loss and absence of melanocytes due to a number of factors is responsible for vitiligo; known to be the commonest disorder of pigmentation. The aim of the study was to assess clinically and dermoscopically the efficacy of topical trichloroacetic acid 70%
Ahmed R. Elshahed   +3 more
doaj   +3 more sources

Methoxsalen deteriorative effects on the testicular parenchyma and testosterone synthesis gene expression in male rats [PDF]

open access: yesScientific Reports
Studies show that psoralens have adverse effects on the reproductive system. This study investigated the impact of methoxsalen in combination with UVA on testicular parenchyma and the expression level of testosterone synthesis pathway genes as well as ...
Zahra Gholipour   +5 more
doaj   +3 more sources

Novel inactivation of the causative fungal pathogen of white-nose syndrome with methoxsalen plus ultraviolet A or B radiation.

open access: goldPLoS ONE, 2020
White-nose syndrome is a fungal disease responsible for the rapid decline of North American bat populations. This study addressed a novel method for inactivating Pseudogymnoascus destructans, the causative agent of WNS, using ultraviolet A (UVA) or B ...
Colin J Hartman   +3 more
doaj   +5 more sources

Protective Effects of Methoxsalen Supplementation on Chronic Alcohol-induced Osteopenia and Steatosis in Rats [PDF]

open access: goldMolecules, 2020
Osteopenia or osteoporosis occurs frequently in alcoholics and patients with alcoholic fatty liver disease. Methoxsalen (MTS), 8-methoxypsoralen, improved osteoporosis in ovariectomized and diabetic mouse models; however, its effects on alcohol-induced ...
Ju Ri Ham   +3 more
doaj   +3 more sources

Randomized controlled study of ECP with methoxsalen as first-line treatment of patients with moderate to severe cGVHD

open access: goldBlood Advances, 2019
: The investigation of extracorporeal photopheresis (ECP) plus standard of care (SoC) (SoC+ECP) in chronic graft-versus-host disease (cGVHD) within prospective, randomized clinical studies is limited, despite its frequent clinical use. This phase 1/pilot
Madan Jagasia   +12 more
doaj   +3 more sources

Methoxsalen Inhibits the Acquisition of Nicotine Self-Administration: Attenuation by Cotinine Replacement in Male Rats. [PDF]

open access: bronzeNicotine Tob Res
INTRODUCTION Cigarette smoking remains the leading preventable cause of disease and death. Nicotine is the primary reinforcing ingredient in cigarettes sustaining addiction.
Ding ZM, Neslund EM, Sun D, Tan X.
europepmc   +4 more sources

Stability-indicating RP-HPLC method for simultaneous determination of methoxsalen and p-aminobenzoic acid in binary combination

open access: diamondBulletin of the Chemical Society of Ethiopia, 2015
An accurate, simple and specific reverse phase LC procedure is established and validated for simultaneous estimation of methoxsalen and p-aminobenzoic acid in pharmaceutical formulated products and human serum.
P. John   +5 more
doaj   +4 more sources

Bullous Eruption Following Methoxsalen Treatment in a Pediatric Patient with Vitiligo Vulgaris

open access: diamondIndian Journal of Paediatric Dermatology
Shekhar Neema   +3 more
doaj   +3 more sources

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