Exploring the mechanism of Liuwei Dihuang formula for promoting melanin synthesis in juvenile zebrafish based on network pharmacology and molecular docking [PDF]
Heliyon, 2023 Background: Vitiligo stands as a challenging skin disorder with limited treatment options available. LiuWei DiHuang formula (LDF), a renowned Traditional Chinese medicine, has exhibited promising results in treating vitiligo over an extended period ...
Dandan Wang +3 more
doaj +2 more sources
Dehydrocostus Lactone Inhibits Microglia‐Mediated Neuroinflammation by Targeting CYP2A6 to Improve Ischemic Brain Injury [PDF]
CNS Neuroscience &Therapeutics, Volume 31, Issue 7, July 2025.Dehydrocostus lactone (DHC) inhibits microglia‐mediated neuroinflammation by targeting CYP2A6, reducing the release of pro‐inflammatory factors and improving nerve function impairment, thereby alleviating ischemic brain injury. ABSTRACT Background Neuroinflammation is an important factor in ischemic stroke.
Xin Shu +7 more
wiley +2 more sources
Single‐Cell Analysis Integrated With Machine Learning Elucidates the Mechanisms of Nucleus Pulposus Cells Apoptosis in Intervertebral Disc Degeneration and Therapeutic Interventions [PDF]
JOR SPINE, Volume 8, Issue 1, March 2025.IVDD has various NPC subgroups, including HT‐CLNP, fibrous NPC, sticky NPC, regulatory NPC, and steady‐state NPC. Furthermore, numerous immune cell infiltrates, particularly monocytes and macrophages, play a crucial role in the evolution of IVDD. Parthenogenesis' key components are Osthole, Columbianadin, and Bergapten, which absorb IVDD by managing ...
Chao Song +8 more
wiley +2 more sources
Group I pharmaceuticals of IARC and associated cancer risks: systematic review and meta-analysis [PDF]
Scientific ReportsWe aimed to summarize the cancer risk among patients with indication of group I pharmaceuticals as stated in monographs presented by the International Agency for Research on Cancer working groups.
Woojin Lim +8 more
doaj +2 more sources
Extracorporeal photopheresis (ECP) in the treatment of chronic lung allograft dysfunction (CLAD): a prospective, multicentre, open-label, randomised controlled trial studying the addition of ECP to standard care in the treatment of bilateral lung transplant patients with CLAD (E-CLAD UK) [PDF]
BMJ Open Respiratory ResearchBackground Long-term survival after lung transplantation is limited compared with other organ transplants. The main cause is development of progressive immune-mediated damage to the lung allograft.
Martin Carby +22 more
doaj +2 more sources
Blood Advances, 2019 : The investigation of extracorporeal photopheresis (ECP) plus standard of care (SoC) (SoC+ECP) in chronic graft-versus-host disease (cGVHD) within prospective, randomized clinical studies is limited, despite its frequent clinical use. This phase 1/pilot
Madan Jagasia +12 more
doaj +2 more sources
Oral methoxsalen photochemotherapy of uncommon photodermatoses
Acta Dermato-Venereologica, 1979 Three uncommon idiopathic photodermatoses, refractory to other treatment, responded to oral psoralen photochemotherapy. Tow females with photosensitivity in association with atopy, one female with persistent light reaction following a systemic drug-induced photosensitivity and an elderly male with actinic reticuloid were treated.
WL Morison +4 more
openalex +4 more sources
Time‐dependent change of T cell receptor clonality: From large plaque parapsoriasis to early mycosis fungoides [PDF]
Skin Res TechnolSkin Research and Technology, Volume 30, Issue 8, August 2024.
Munenari Itoh +2 more
wiley +2 more sources
Bullous Eruption Following Methoxsalen Treatment in a Pediatric Patient with Vitiligo Vulgaris
Indian Journal of Paediatric DermatologyShekhar Neema +3 more
doaj +2 more sources