Methoxsalen inhibited the acquisition of nicotine self-administration: attenuation by cotinine replacement in rats [PDF]
bioRxiv, 2023 Cigarette smoking remains the leading preventable cause of disease and death. Nicotine is the primary reinforcing ingredient in cigarettes sustaining addiction.
Zheng‐Ming Ding +3 more
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Cancer Medicine, 2022 Background This trial explores SM‐88 used with methoxsalen, phenytoin, and sirolimus (MPS) in pretreated metastatic pancreatic ductal adenocarcinoma (mPDAC) Methods Forty‐nine patients were randomized to daily 460 or 920 mg oral SM‐88 with MPS (SM‐88 ...
Marcus S. Noel +11 more
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Exploring the mechanism of Liuwei Dihuang formula for promoting melanin synthesis in juvenile zebrafish based on network pharmacology and molecular docking [PDF]
Heliyon, 2023 Background: Vitiligo stands as a challenging skin disorder with limited treatment options available. LiuWei DiHuang formula (LDF), a renowned Traditional Chinese medicine, has exhibited promising results in treating vitiligo over an extended period ...
Dandan Wang +3 more
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Methoxsalen with Ultraviolet A Therapy [PDF]
Report on carcinogens : carcinogen profiles, 2020 A cohort study of 1,380 psoriasis patients treated with PUVA found that the risk of skin cancer (squamous-cell carcinoma) increased with increasing exposure to PUVA; exposure to high doses of PUVA increased the risk of cancer by more than 50-fold.
National Cancer Institute
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Journal of Advanced Research in Ayurveda Yoga Unani Sidhha & Homeopathy, 2020 Background: Vitiligo is a common acquired disorder of skin depigmentation in varying patterns, varying from small maculae’s with scalloping borders to near total depigmentation of body.
Parvez Khan
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Development and Validation of Ultraviolet Spectroscopic Method for Estimation of Methoxsalen in Bulk Using Methanol and Phosphate Buffer (pH 7.4) [PDF]
Indian Journal of Pharmaceutical Education and Research, 2021 Background: Psoriasis is an inflammatory condition of a body wherein erythematous, sharply demarcated papules and round-shaped plaques appear onto skin due to the hyperproliferation of epidermis.
Shraddha Unde, Nalini Kurup
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Plant-Assisted Synthesis, Phytochemical Profiling, and Bioactivity Evaluation of Copper Nanoparticles Derived from Tordylium trachycarpum (Apiaceae) [PDF]
BiomoleculesTordylium trachycarpum Boiss. (Apiaceae) has long been used by traditional healers in the Kurdistan Region of Iraq to alleviate gastrointestinal disorders and oral inflammation; however, its phytochemical composition and pharmacological properties remain
Venos Saeed Abdullah +2 more
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Group I pharmaceuticals of IARC and associated cancer risks: systematic review and meta-analysis [PDF]
Scientific ReportsWe aimed to summarize the cancer risk among patients with indication of group I pharmaceuticals as stated in monographs presented by the International Agency for Research on Cancer working groups.
Woojin Lim +8 more
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Senotherapeutic Potential of Araliadiol in Senescent Human Dermal Fibroblasts: An In Vitro Study Using Three Senescence Models [PDF]
PharmaceuticsBackground/Objectives: With the rapid aging of the global population, the interest in therapies for age-related diseases has increased substantially. The skin is particularly important, as aging-related changes are visible and negatively impact quality ...
Seokmuk Park +6 more
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The adverse effects of the methoxsalen and ultraviolent A radiation on spermatogenesis in mice
Iranian Journal of Reproductive Medicine, 2015 Background: Different investigation showed that 5-methoxypsoralen and 8- methoxypsoralen reduce birth rates in the rats. Objective: In this study we worked out the effect of methoxsalen together with ultraviolent A (UVA) radiation on mature Balb/C mice ...
Mona Farhadi +4 more
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