Results 21 to 30 of about 2,832 (233)

Methoxsalen with Ultraviolet A Therapy [PDF]

open access: hybridReport on carcinogens : carcinogen profiles, 2020
A cohort study of 1,380 psoriasis patients treated with PUVA found that the risk of skin cancer (squamous-cell carcinoma) increased with increasing exposure to PUVA; exposure to high doses of PUVA increased the risk of cancer by more than 50-fold.

openalex   +2 more sources

DETERMINATION OF RESIDUAL DIMETHYL SULFATE IN METHOXSALEN DRUG SUBSTANCE BY PRE-COLUMN DERIVATIZATION WITH STATIC HEADSPACE GAS CHROMATOGRAPHY [PDF]

open access: yesInternational Journal of Pharmacy and Pharmaceutical Sciences, 2018
Objective: Dimethyl sulfate has been highlighted as potential genotoxic and carcinogenic impurity. A sensitive Headspace gas chromatography (HS-GC) method with pre-column derivatization was developed and validated for the determination of dimethyl ...
A. Anerao, B. Patil, N. Pradhan
semanticscholar   +3 more sources

The adverse effects of the methoxsalen and ultraviolent A radiation on spermatogenesis in mice [PDF]

open access: greenIranian Journal of Reproductive Medicine, 2015
Background: Different investigation showed that 5-methoxypsoralen and 8- methoxypsoralen reduce birth rates in the rats. Objective: In this study we worked out the effect of methoxsalen together with ultraviolent A (UVA) radiation on mature Balb/C mice ...
Mona Farhadi   +4 more
doaj   +1 more source

Oral methoxsalen photochemotherapy of mycosis fungoides [PDF]

open access: bronzeCancer, 1976
The cutaneous manifestations of mycosis fungoides have been successfully treated in nine patients for 16 to 28 months with oral methoxsalen and subsequent irradiation with longwave ultraviolet light. The efficacy of this therapy was confirmed in one patient, who showed complete clearing of generalized plaques after 1 month (12 treatments) except for a ...
Harley A. Haynes   +4 more
openaire   +4 more sources

Method Development and Validation of Methoxsalen

open access: goldInternational Journal for Research in Applied Science and Engineering Technology, 2023
Bhagyashri Gayke
openalex   +2 more sources

Oral methoxsalen photochemotherapy of uncommon photodermatoses

open access: hybridActa Dermato-Venereologica, 1979
Three uncommon idiopathic photodermatoses, refractory to other treatment, responded to oral psoralen photochemotherapy. Tow females with photosensitivity in association with atopy, one female with persistent light reaction following a systemic drug-induced photosensitivity and an elderly male with actinic reticuloid were treated.
W L, Morison   +4 more
openaire   +4 more sources

Catalytic Synthesis of β‐(Hetero)arylethylamines: Modern Strategies and Advances

open access: yesAngewandte Chemie, Volume 135, Issue 41, October 9, 2023., 2023
This review provides a comprehensive overview of the recent progresses made in the catalytic synthesis of β‐(hetero)arylethylamines, which have become widespread scaffolds in drug discovery. During the past decade, this field of research has expanded tremendously thanks to the development of enabling technologies such as C−H activation, photocatalysis,
Valentyn Pozhydaiev   +3 more
wiley   +2 more sources

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