Results 41 to 50 of about 911,489 (397)

SUVH1, a Su(var)3-9 family member, promotes the expression of genes targeted by DNA methylation. [PDF]

, 2015
Transposable elements are found throughout the genomes of all organisms. Repressive marks such as DNA methylation and histone H3 lysine 9 (H3K9) methylation silence these elements and maintain genome integrity.
Chen, Xuemei, Gao, Lei, Kim, Yun Ju, Li, Shaofang, Li, Shengben, Liu, Lin, Zhao, Yuanyuan   +6 more
core   +2 more sources

Methyl gallate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND (SYSTEMATIC NAME: methyl 3,4,5-trihydroxy-benzoate), C(8)H(8)O(5), is composed of essentially planar mol-ecules [maximum departures from the mean carbon and oxygen skeleton plane of 0.0348 (10) Å]. The H atoms of the three hydroxyl groups, which function as hydrogen-bond donors and acceptors simultaneously ...
Silvina Pagola, Deborah Bebout
openaire   +3 more sources

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

Bioinform., 2014
MOTIVATION The recently released Infinium HumanMethylation450 array (the '450k' array) provides a high-throughput assay to quantify DNA methylation (DNAm) at ∼450 000 loci across a range of genomic features.
Martin J. Aryee, A. Jaffe, H. C. Bravo, C. Ladd-Acosta, A. Feinberg, K. Hansen, R. Irizarry   +6 more
semanticscholar   +1 more source

Isolation and biosynthesis of an unsaturated fatty acid with unusual methylation pattern from a coral-associated bacterium Microbulbifer sp.

Beilstein Journal of Organic Chemistry, 2019
(2Z,4E)-3-Methyl-2,4-decadienoic acid (1) was identified as a major metabolite from a culture extract of a marine bacterium Microbulbifer which was collected from a stony coral Porites sp.
Amit Raj Sharma, Enjuro Harunari, Tao Zhou, Agus Trianto, Yasuhiro Igarashi   +4 more
doaj   +1 more source

Biliary Tract Cancers: Treatment Updates and Future Directions in the Era of Precision Medicine and Immuno-Oncology

Frontiers in Oncology, 2021
The effective management of biliary tract cancers (BTCs) has been hampered by limited options for systemic therapy. In recent years, the focus on precision medicine has made technologies such as next-generation sequencing (NGS) accessible to clinicians ...
Ashish Manne, Edward Woods, Allan Tsung, Arjun Mittra   +3 more
doaj   +1 more source

Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors. [PDF]

, 2014
BackgroundIn 31 solid tumor patients treated with the demethylating agent decitabine, we performed tumor biopsies before and after the first cycle of decitabine and used immunohistochemistry (IHC) to assess whether decitabine increased expression of ...
A Kumari, AS Yang, C Festuccia, C Zeller, CA Stidley, CJ Piyathilake, D Ma, D Matei, D Shang, DJ Stewart, DJ Stewart, DJ Stewart, DJ Stewart, DJ Stewart, DJ Stewart, DW Shen, E Gordian, E San Jose-Eneriz, EA Braga, F Crea, F Fang, H Iwata, H Kantarjian, H Kroeger, HM Kantarjian, J Charlet, J Shia, JA Plumb, JP Issa, JP Issa, JS Kim, K Ghoshal, K Onda, K Ramachandran, K Tikoo, KY Tse, L Ding, L Rothem, MA Kane, ML Orta, NH Nabilsi, R Zhao, RH Finnell, S Fu, S Vijayaraghavalu, SB Baylin, SS Muerkoster, T Tanaka, TB Lee, VF Chekhun, X Chang, XJ Liang, Y Li, Y Oki, Y Zhang, ZG Liu   +55 more
core   +2 more sources

DNA methylation GrimAge strongly predicts lifespan and healthspan

Aging, 2019
It was unknown whether plasma protein levels can be estimated based on DNA methylation (DNAm) levels, and if so, how the resulting surrogates can be consolidated into a powerful predictor of lifespan.
A. Lu, Austin Quach, James G. Wilson, A. Reiner, A. Aviv, K. Raj, L. Hou, A. Baccarelli, Yun Li, J. Stewart, E. Whitsel, T. Assimes, L. Ferrucci, S. Horvath   +13 more
semanticscholar   +1 more source

The Downregulation of Prognosis- and Immune Infiltration-Related Gene CYFIP2 Serves as a Novel Target in ccRCC

International Journal of General Medicine, 2021
Junwei Tong,1– 3,* Xiangui Meng,1– 3,* Qingyang Lv,1– 3,* Hongwei Yuan,1– 3 Weiquan Li,1– 3 Wen Xiao,1– 3 Xiaoping Zhang1– 3 1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan,
Tong J, Meng X, Lv Q, Yuan H, Li W, Xiao W, Zhang X   +6 more
doaj  

DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with Ulcerative Colitis (UC) [PDF]

, 2010
Introduction: Epigenetic marking such as DNA methylation influence gene transcription and chromosomal stability and may also be affected by environmental exposures.
Arasaradnam, Ramesh P., Bradburn, Mike, Kelly, S. B., Khoo, K. T. J., Mathers, John C.   +4 more
core   +1 more source

Methylation landscape in the genome of higher plants of agronomical interest [PDF]

, 2003
In eukaryotic cells the methylation of cytosines in DNA is an essential mechanism which is implied in the dynamic organization of the genome structure, in relation to genes expression. Plant genomes contain a significant proportion and variable according
Balogh, A., Dandouras, I., Fornaçon, K.-H., Georgescu, E., Glassmeier, K.-H., Motschmann, U., Narita, Y., Rème, H., Sauer, K., Schäfer, S.   +9 more
core   +2 more sources