Results 41 to 50 of about 641,368 (381)

Effect of receptor cooperativity on methylation dynamics in bacterial chemotaxis with weak and strong gradient [PDF]

open access: yesPhysical Review E 105, 014411 (2022), 2022
We study methylation dynamics of the chemoreceptors as an {\sl E.coli} cell moves around in a spatially varying chemo-attractant environment. We consider attractant concentration with strong and weak spatial gradient. During the uphill and downhill motion of the cell along the gradient, we measure the temporal variation of average methylation level of ...
arxiv   +1 more source

DNA methylation patterns and epigenetic memory.

open access: yesGenes & Development, 2002
The character of a cell is defined by its constituent proteins, which are the result of specific patterns of gene expression. Crucial determinants of gene expression patterns are DNA-binding transcription factors that choose genes for transcriptional ...
A. Bird
semanticscholar   +1 more source

ChemInform Abstract: Alkyl Methyl Carbonates as Methylating Agents. The O‐Methylation of Phenols. [PDF]

open access: yesChemInform, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
PEROSA, Alvise   +3 more
openaire   +3 more sources

Tet Proteins Regulate Neutrophil Granulation in Zebrafish through Demethylation of socs3b mRNA

open access: yesCell Reports, 2021
Summary: Tet proteins (Tet1/2/3) convert 5-methylcytosine (5mC) to 5-hydroxy-methylcytosine (5hmC), initiating the process of active demethylation to regulate gene expression.
Kelly M. Banks, Yahui Lan, Todd Evans
doaj  

Modeling DNA methylation dynamics with approaches from phylogenetics [PDF]

open access: yesBioinformatics 30 (2014) i408-i414, 2014
Methylation of CpG dinucleotides is a prevalent epigenetic modification that is required for proper development in vertebrates, and changes in CpG methylation are essential to cellular differentiation. Genome-wide DNA methylation assays have become increasingly common, and recently distinct stages across differentiating cellular lineages have been ...
arxiv   +1 more source

From trans-methylation to cytosine methylation: Evolution of the methylation hypothesis of schizophrenia [PDF]

open access: yesEpigenetics, 2009
The role of methylation in the history of psychiatry has traversed a storied path. The original trans-methylation hypothesis was proposed at a time when chlorpromazine had been synthesized but not yet marketed as an antipsychotic (Thorazine).
Erbo Dong   +4 more
openaire   +3 more sources

Epigenetic Alterations of the Promoter Region of the POMC Gene in Adolescent Depressive Disorder Patients with Nonsuicidal Self-Injury Behaviors [Erratum]

open access: yesPsychology Research and Behavior Management, 2021
Zheng D, Bi X, Zhang T, et al. Psychol Res Behav Manag. 2020;13:997–1008. The authors have advised that there are several errors in the published paper which were introduced by the Editorial staff during the publication process ...
Zheng D   +9 more
doaj  

Synthesis and biological activity of methylated derivatives of the Pseudomonas metabolites HHQ, HQNO and PQS

open access: yesBeilstein Journal of Organic Chemistry, 2019
Selectively methylated analogues of naturally occurring 2-heptyl-4(1H)-quinolones, which are alkaloids common within the Rutaceae family and moreover are associated with quorum sensing and virulence of the human pathogen Pseudomonas aeruginosa, have been
Sven Thierbach   +3 more
doaj   +1 more source

A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

open access: yesNature Chemical Biology, 2013
N6-methyladenosine (m6A) is the most prevalent and reversible internal modification in mammalian messenger and non-coding RNAs. We report here that human METTL14 catalyzes m6A RNA methylation.
Jianzhao Liu   +12 more
semanticscholar   +1 more source

Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements [PDF]

open access: yes, 2013
Background: Recent assays for individual-specific genome-wide DNA methylation profiles have enabled epigenome-wide association studies to identify specific CpG sites associated with a phenotype. Computational prediction of CpG site-specific methylation levels is important, but current approaches tackle average methylation within a genomic locus and are
arxiv   +1 more source

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