Results 71 to 80 of about 1,050,423 (388)
Current Oncology, 2023 Tumor evolution to evade immune surveillance is a hallmark of carcinogenesis, and the modulation of tumor immunogenicity has been a challenge to present therapeutic responses in immunotherapies alone for numerous cancers.
Dong Yeul Lee +2 more
doaj +1 more source
The Journal of General Physiology, 1966 The methylated bases of DNA are formed by the transfer of the methyl group from S-adenosylmethionine to a polynucleotide acceptor. This transfer is catalyzed by highly specific enzymes which recognize a limited number of available sites in the DNA. The mechanism for the recognition is presently unknown.
Malcolm Gefter +3 more
openaire +3 more sources
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Interferon beta treatment is a potent and targeted epigenetic modifier in multiple sclerosis
Frontiers in Immunology, 2023 IntroductionMultiple Sclerosis (MS) has a complex pathophysiology that involves genetic and environmental factors. DNA methylation (DNAm) is one epigenetic mechanism that can reversibly modulate gene expression.
Alexandre Xavier +17 more
doaj +1 more source
In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children. [PDF]
, 2019 BackgroundMaternal smoking during pregnancy is a risk factor for chronic disease later in life and has been associated with variability of DNA methylation at specific cytosine-phosphate-guanine (CpG) loci.
Barker +47 more
core +1 more source
On the electronic structure of methyl butyrate and methyl valerate [PDF]
The European Physical Journal D, 2020 AbstractWe present novel results of the analysis of the electronic structure of two aliphatic esters: methyl butyrate and methyl valerate. High-resolution photoabsorption spectra were collected and analyzed over the energy range 4.0–10.8 eV and showed for both the molecules not only a clear band of the HOMO to LUMO transition, but also vibronic ...
Śmiałek, Małgorzata +7 more
openaire +5 more sources
DNA methylation arrays as surrogate measures of cell mixture distribution
BMC Bioinformatics, 2012 There has been a long-standing need in biomedical research for a method that quantifies the normally mixed composition of leukocytes beyond what is possible by simple histological or flow cytometric assessments.
E. Houseman +7 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Kouqiang hemian waike zazhi[Objective:] To observe the methylation and protein levels of glutathione peroxidase 3 (GPX3) in malignant pleomorphic adenoma (MPA) tissue and its clinical significance.
LIU Xiao, SUN Jiangwei, ZHOU Jing
doaj +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2015 The crystal structures of three methylated hydrazine carbamate derivatives prepared by multi-step syntheses from l-serine are presented, namely benzyl N-{(E)-1-[2-(4-cyanobenzylidene)-1-methylhydrazinyl]-3-hydroxy-1-oxopropan-2-yl}carbamate, C20H20N4O4 ...
Thais C. M. Noguiera +5 more
doaj +1 more source