Results 51 to 60 of about 25,402 (289)

3-Methylcholanthrene, which binds to the arylhydrocarbon receptor, inhibits proliferation and differentiation of osteoblasts in vitro and ossification in vivo.

Endocrinology, 2002
3-Methylcholanthrene (3MC) is a ligand for arylhydrocarbon receptor (AhR), which binds dioxin. We examined the effects of 3MC on the proliferation and differentiation of osteoblasts using cultures of rat calvarial osteoblast-like cells (ROB cells) and ...
M. Naruse, Y. Ishihara, S. Miyagawa‐Tomita, A. Koyama, H. Hagiwara   +4 more
semanticscholar   +1 more source

Enhancement of drug oxidation and conjugation by carcinogens in different rat tissues [PDF]

, 1972
OBJECTIVE After endoscopic third ventriculostomy (ETV), some patients develop recurrent symptoms of hydrocephalus. The optimal treatment for these patients is not clear: repeat ETV (re-ETV) or CSF shunting.
Breimer, Gerben E., Brusse-Keizer, Marjolein, Buis, Dennis R., Dammers, Ruben, Delye, Hans, Hoving, Eelco W., Woerdeman, Peter A.   +6 more
core   +2 more sources

Deletion of Forkhead Box M1 transcription factor from respiratory epithelial cells inhibits pulmonary tumorigenesis. [PDF]

PLoS ONE, 2009
The Forkhead Box m1 (Foxm1) protein is induced in a majority of human non-small cell lung cancers and its expression is associated with poor prognosis.
I-Ching Wang, Lucille Meliton, Xiaomeng Ren, Yufang Zhang, David Balli, Jonathan Snyder, Jeffrey A Whitsett, Vladimir V Kalinichenko, Tanya V Kalin   +8 more
doaj   +1 more source

3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha.

Cancer Research, 2006
3-Methylcholanthrene (3MC) is an aryl hydrocarbon receptor (AhR) agonist, and it has been reported that 3MC induces estrogenic activity through AhR-estrogen receptor alpha (ER alpha) interactions.
M. Abdelrahim, E. Ariazi, Kyounghyun Kim, Shaheen Khan, R. Barhoumi, R. Burghardt, Shengxi Liu, Denise S. Hill, R. Finnell, B. Wlodarczyk, V. Jordan, S. Safe   +11 more
semanticscholar   +1 more source

Inhibitory effect of isologous regional lymphnode cells from the methylcholanthrene-induced sarcoma bearing mice on the tumor in vivo [PDF]

, 1970
MC-induced sarcomas produced under the skin on the back between　scapulas of C3H mice were transplanted　successively to the mice of the　same strain.
Kashihara, Eiji
core   +1 more source

EMAP II Expression Is Increased on Peripheral Blood Cells from Non-Hodgkin Lymphoma

Journal of Immunology Research, 2022
Tumor immune evasion is a lineament of cancer. Endothelial monocyte activating polypeptide-II (EMAP II) has been assumed to impact tumor immune escape significantly.
Manal Mohamed Saber
doaj   +1 more source

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

Animal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang, Xianbin Zhao, Lili Tan, Pingxinyi Que, Tong Zhao, Wei Huang, Dejiao Yao, Songqi Tang   +7 more
wiley   +1 more source

Transformation of SV40-immortalized human uroepithelial cells by 3-methylcholanthrene increases IFN- and Large T Antigen-induced transcripts

Cancer Cell International, 2010
Background Simian Virus 40 (SV40) immortalization followed by treatment of cells with 3-methylcholanthrene (3-MC) has been used to elicit tumors in athymic mice.
Easton Marilyn J, Yoon Lawrence W, George Michael, Moore Tanya M, Crosby Lynn M, Ni Hong, Morgan Kevin T, DeAngelo Anthony B   +7 more
doaj   +1 more source

Effect of interleukin 12 on tumor induction by 3-methylcholanthrene.

Proceedings of the National Academy of Sciences of the United States of America, 1996
Interleukin (IL)-12 has strong antitumor activity in transplantable tumor systems in the mouse. The present study was designed to determine whether tumor induction by 3-methylcholanthrene (3-MC), a carcinogenic hydrocarbon, can be inhibited by IL-12 ...
Y. Noguchi, A. Jungbluth, E. Richards, L. Old   +3 more
semanticscholar   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source