Results 231 to 240 of about 341,991 (305)

Regulation of RNA methylation linked to drug resistance in gastric cancer. [PDF]

Front Cell Dev Biol
Yang Z, Ma Y, Xu Z, Liu H, Gu X, Sun J.
europepmc   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source

MORF4L1 regulation and its role in chromatin remodeling, DNA damage, cellular senescence, and cardiometabolic disease. [PDF]

Vascul Pharmacol
Tanni FY, Zoni RN, Faysal MA, Sun X.
europepmc   +1 more source

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

Emerging roles of tRNA modification-mediated codon-specific translational reprogramming in cancer biology. [PDF]

Cell Death Dis
Wang H, Zhang J, Jiang C, Xu S.
europepmc   +1 more source

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song, Han‐Xu Jin, Yuan‐Xin Sun, Wen‐Hui Kou, Xiao‐Ning Niu, Huan‐Huan Wang, Ting‐Ting Zhong, Ping Gu   +7 more
wiley   +1 more source

Molecular mechanisms and therapeutic strategies: DNA methylation in pancreatic cancer. [PDF]

Cancer Biol Ther
Liu J, Xie J, Ding Y.
europepmc   +1 more source

Puerarin alleviates diabetic atherosclerosis through controlling the follistatin-like 1 related inflammation. [PDF]

Coron Artery Dis
Chen J, Hu Z, Fang M, Hu X, Pan X, Ni X.
europepmc   +1 more source

Molecular timekeepers: the curious alliance of redox, repair, and protective proteins in preserving seed longevity. [PDF]

Crop Health
Das A, Majee M.
europepmc   +1 more source

The effects of genetically determined plasma methyltransferases on digestive system cancers: a comprehensive bidirectional two-sample Mendelian randomization analysis. [PDF]

Discov Oncol
Zhang C, Li X, Dong Z, Weng Y, Yu W, Cai X.   +5 more
europepmc   +1 more source