Results 21 to 30 of about 64,067 (262)
The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase [PDF]
Nucleic Acids Research, 2003 The DNA methyltransferases, Dnmts, are the enzymes responsible for methylating DNA in mammals, which leads to gene silencing. Repression by DNA methylation is mediated partly by recruitment of the methyl-CpG-binding protein MeCP2. Recently, MeCP2 was shown to associate and facilitate histone methylation at Lys9 of H3, which is a key epigenetic ...
Fuks, François +3 more
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Expression of DNMTs and H3K9ac in Ameloblastoma and Ameloblastic Carcinoma
Frontiers in Oral Health, 2021 Objectives: DNA methyltransferases (DNMTs) and the histone modification H3K9ac are epigenetic markers. This study aimed to describe the immunohistochemical expression of DNMT1, DNMT3A, DNMT3B, and H3K9ac in the dental follicle (DF), ameloblastoma (AME ...
Gleyson Kleber do Amaral-Silva +9 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 The acquisition of antibiotics resistance is a major clinical challenge limiting the effective prevention and treatment of the deadliest human infectious disease tuberculosis.
Sabeeha Ali +9 more
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Pathogens, 2023 Flavobacterium psychrophilum (Fp), the causative agent of Bacterial Cold-Water disease in salmonids, causes substantial losses in aquaculture. Bacterial outer membrane vesicles (OMVs) contain several virulence factors, enzymes, toxins, and nucleic acids ...
Pratima Chapagain +2 more
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Gene Expression Profile of RNA N1-methyladenosine methyltransferases [PDF]
E3S Web of Conferences, 2020 N1-methyladenosine (m1A) is a kind of common and abundant methylation modification in eukaryotic mRNA and long-chain non-coding RNA. Nucleoside methyltransferase (MTase) of m1A is a diverse protein family, which is characterized by the presence of ...
Rao Mingzhu
doaj +1 more source
RmtC and RmtF 16S rRNA Methyltransferase in NDM-1–Producing Pseudomonas aeruginosa
Emerging Infectious Diseases, 2015 We investigated 16S rRNA methyltransferases in 38 blaNDM-1–positive Pseudomonas aeruginosa isolates and found RmtC in 3 isolates, 1 of which also harbored RmtF.
Mohibur Rahman +7 more
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The Methylation Game: Epigenetic and Epitranscriptomic Dynamics of 5-Methylcytosine
Frontiers in Cell and Developmental Biology, 2022 DNA and RNA methylation dynamics have been linked to a variety of cellular processes such as development, differentiation, and the maintenance of genome integrity.
Adele Alagia, Monika Gullerova
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Frontiers in Cellular and Infection Microbiology, 2019 Mycobacterium tuberculosis bifunctional enzyme GlmU is a novel target for anti-TB drugs and is involved in glycosyl donor UDP-N-acetylglucosamine biosynthesis.
Changming Chen +8 more
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Methyltransferases of gentamicin biosynthesis [PDF]
Proceedings of the National Academy of Sciences, 2018 Gentamicin C complex from Micromonospora echinospora remains a globally important antibiotic, and there is revived interest in the semisynthesis of analogs that might show improved therapeutic properties. The complex consists of five components differing in their methylation pattern at one or more sites in the ...
Sicong Li +8 more
openaire +2 more sources
Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications
BMC Medicine, 2011 Soft tissue sarcomas of childhood are a group of heterogeneous tumors thought to be derived from mesenchymal stem cells. Surgical resection is effective only in about 50% of cases and resistance to conventional chemotherapy is often responsible for ...
Giordano Antonio +4 more
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