Results 11 to 20 of about 64,774 (259)

Methylation of Ribosomal RNA: A Mitochondrial Perspective

Frontiers in Genetics, 2020
Ribosomal RNA (rRNA) from all organisms undergoes post-transcriptional modifications that increase the diversity of its composition and activity. In mitochondria, specialized mitochondrial ribosomes (mitoribosomes) are responsible for the synthesis of 13
M. Isabel G. Lopez Sanchez, M. Isabel G. Lopez Sanchez, Miriam Cipullo, Miriam Cipullo, Shreekara Gopalakrishna, Shreekara Gopalakrishna, Anas Khawaja, Anas Khawaja, Joanna Rorbach, Joanna Rorbach   +9 more
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Association of N6-methyladenosine with viruses and virally induced diseases

Frontiers in Bioscience-Landmark, 2020
N6-methyladenosine (m6A) modification, which alters gene expression, is the most prevalent internal modification of eukaryotic mRNA. m6A modification is dynamic and reversible that is regulated by three associated protein groups: methyltransferases or ...
Fang Wu, Wenzhao Cheng, Feiyuan Zhao, Mingqing Tang, Yong Diao, Ruian Xu   +5 more
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The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase [PDF]

Nucleic Acids Research, 2003
The DNA methyltransferases, Dnmts, are the enzymes responsible for methylating DNA in mammals, which leads to gene silencing. Repression by DNA methylation is mediated partly by recruitment of the methyl-CpG-binding protein MeCP2. Recently, MeCP2 was shown to associate and facilitate histone methylation at Lys9 of H3, which is a key epigenetic ...
Fuks, François, Hurd, Paul J., Deplus, Rachel, Kouzarides, Tony   +3 more
openaire   +3 more sources

Expression of DNMTs and H3K9ac in Ameloblastoma and Ameloblastic Carcinoma

Frontiers in Oral Health, 2021
Objectives: DNA methyltransferases (DNMTs) and the histone modification H3K9ac are epigenetic markers. This study aimed to describe the immunohistochemical expression of DNMT1, DNMT3A, DNMT3B, and H3K9ac in the dental follicle (DF), ameloblastoma (AME ...
Gleyson Kleber do Amaral-Silva, Thayná Melo de Lima Morais, Vivian Petersen Wagner, Manoela Domingues Martins, Eduardo Rodrigues Fregnani, Fernando Augusto Soares, André Caroli Rocha, Helder Rabelo Pontes, Alan Roger Santos-Silva, Pablo Agustin Vargas   +9 more
doaj   +1 more source

The M. tuberculosis Rv1523 Methyltransferase Promotes Drug Resistance Through Methylation-Mediated Cell Wall Remodeling and Modulates Macrophages Immune Responses

Frontiers in Cellular and Infection Microbiology, 2021
The acquisition of antibiotics resistance is a major clinical challenge limiting the effective prevention and treatment of the deadliest human infectious disease tuberculosis.
Sabeeha Ali, Aquib Ehtram, Naresh Arora, P. Manjunath, P. Manjunath, Deodutta Roy, Nasreen Z. Ehtesham, Seyed E. Hasnain, Seyed E. Hasnain, Seyed E. Hasnain   +9 more
doaj   +1 more source

Dual RNA-Seq of Flavobacterium psychrophilum and Its Outer Membrane Vesicles Distinguishes Genes Associated with Susceptibility to Bacterial Cold-Water Disease in Rainbow Trout (Oncorhynchus mykiss)

Pathogens, 2023
Flavobacterium psychrophilum (Fp), the causative agent of Bacterial Cold-Water disease in salmonids, causes substantial losses in aquaculture. Bacterial outer membrane vesicles (OMVs) contain several virulence factors, enzymes, toxins, and nucleic acids ...
Pratima Chapagain, Ali Ali, Mohamed Salem   +2 more
doaj   +1 more source

Gene Expression Profile of RNA N1-methyladenosine methyltransferases [PDF]

E3S Web of Conferences, 2020
N1-methyladenosine (m1A) is a kind of common and abundant methylation modification in eukaryotic mRNA and long-chain non-coding RNA. Nucleoside methyltransferase (MTase) of m1A is a diverse protein family, which is characterized by the presence of ...
Rao Mingzhu
doaj   +1 more source

RmtC and RmtF 16S rRNA Methyltransferase in NDM-1–Producing Pseudomonas aeruginosa

Emerging Infectious Diseases, 2015
We investigated 16S rRNA methyltransferases in 38 blaNDM-1–positive Pseudomonas aeruginosa isolates and found RmtC in 3 isolates, 1 of which also harbored RmtF.
Mohibur Rahman, Kashi Nath Prasad, Ashutosh Pathak, Binod Kumar Pati, Avinash Singh, Cristina M. Ovejero, Saheem Ahmad, Bruno Gonzalez-Zorn   +7 more
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The Methylation Game: Epigenetic and Epitranscriptomic Dynamics of 5-Methylcytosine

Frontiers in Cell and Developmental Biology, 2022
DNA and RNA methylation dynamics have been linked to a variety of cellular processes such as development, differentiation, and the maintenance of genome integrity.
Adele Alagia, Monika Gullerova
doaj   +1 more source

The Inhibitory Effect of GlmU Acetyltransferase Inhibitor TPSA on Mycobacterium tuberculosis May Be Affected Due to Its Methylation by Methyltransferase Rv0560c

Frontiers in Cellular and Infection Microbiology, 2019
Mycobacterium tuberculosis bifunctional enzyme GlmU is a novel target for anti-TB drugs and is involved in glycosyl donor UDP-N-acetylglucosamine biosynthesis.
Changming Chen, Xiuyan Han, Qiulong Yan, Chao Wang, Liqiu Jia, Ayaz Taj, Lizhe Zhao, Yufang Ma, Yufang Ma   +8 more
doaj   +1 more source