Results 51 to 60 of about 175,165 (326)
De novo transcriptome sequencing in Bixa orellana to identify genes involved in methylerythritol phosphate, carotenoid and bixin biosynthesis. [PDF]
, 2015 BackgroundBixin or annatto is a commercially important natural orange-red pigment derived from lycopene that is produced and stored in seeds of Bixa orellana L.
Aguilar-Espinosa, Margarita +5 more
core +3 more sources
The Roles of Human DNA Methyltransferases and Their Isoforms in Shaping the Epigenome
Genes, 2019 A DNA sequence is the hard copy of the human genome and it is a driving force in determining the physiological processes in an organism. Concurrently, the chemical modification of the genome and its related histone proteins is dynamically involved in ...
Hemant Gujar, D. Weisenberger, G. Liang
semanticscholar +1 more source
Biology, 2015 A decline in long-term memory (LTM) formation is a common feature of the normal aging process, which corresponds with abnormal expression of memory-related genes in the aged hippocampus. Epigenetic modulation of chromatin structure is required for proper
Sarah J. Morse +4 more
doaj +1 more source
Targeting Viral Methyltransferases: An Approach to Antiviral Treatment for ssRNA Viruses
Viruses, 2022 Methyltransferase enzymes have been associated with different processes within cells and viruses. Specifically, within viruses, methyltransferases are used to form the 5′cap-0 structure for optimal evasion of the host innate immune system. In this paper,
Peter Ramdhan, Chenglong Li
doaj +1 more source
Coordinated actions of microRNAs with other epigenetic factors regulate skeletal muscle development and adaptation [PDF]
, 2017 Epigenetics plays a pivotal role in regulating gene expression in development, in response to cellular stress or in disease states, in virtually all cell types.
Adamo, Sergio +3 more
core +1 more source
Epigenetics, 2017 Accumulating evidence has recently shown that protein methyltransferases and demethylases are crucial regulators in either maintaining pluripotent states or inducing differentiation of embryonic stem cells. These enzymes control pluripotent signatures by
Theodore Vougiouklakis +2 more
doaj +1 more source
Journal of Infection in Developing Countries, 2015 This item has no abstract. Follow the links belo to access the full text.
Joel Filgona +2 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2023 Neurodevelopmental disorders encompass a group of debilitating diseases presenting with motor and cognitive dysfunction, with variable age of onset and disease severity.
Charlotte Roth +5 more
doaj +1 more source
Structural basis for DNMT3A-mediated de novo DNA methylation. [PDF]
, 2018 DNA methylation by de novo DNA methyltransferases 3A (DNMT3A) and 3B (DNMT3B) at cytosines is essential for genome regulation and development. Dysregulation of this process is implicated in various diseases, notably cancer.
Chen, Dongliang +11 more
core +2 more sources
Aging Cell, 2019 Methionine restriction (MetR) extends lifespan across different species and exerts beneficial effects on metabolic health and inflammatory responses. In contrast, certain cancer cells exhibit methionine auxotrophy that can be exploited for therapeutic ...
A. Parkhitko +3 more
semanticscholar +1 more source