Results 21 to 30 of about 2,934 (153)
Abstract Objective To validate the diagnoses and to investigate epidemiological data from an international, non‐clinic‐based, and large (n = 1604) survey of participants with cluster headache. Background There are several limitations in current epidemiological data in cluster headache including a lack of large non‐clinic‐based studies.
Larry I. Schor +5 more
wiley +1 more source
Changes in use of acute and preventive medications for migraine after erenumab initiation over 12 months: A United States retrospective cohort study. [PDF]
Abstract Objective To assess changes in real‐world use of acute and preventive medications for migraine over a 12‐month follow‐up period in the United States following initiation of the anti‐calcitonin gene‐related peptide (CGRP) pathway monoclonal antibody (mAb) erenumab.
Multani JK +10 more
europepmc +2 more sources
Corticotropin-releasing factor (CRF), urotensin I (UI) and serotonin (5-HT) are generally recognized as key regulators of the anorexigenic stress response in vertebrates, yet the proximal effects and potential interactions of these central messengers on ...
Van A. Ortega +2 more
doaj +1 more source
Background Descending pronociceptive pathways may be implicated in states of persistent pain. Paw skin incision is a well-established postoperative pain model that causes behavioral nociceptive responses and enhanced excitability of spinal dorsal horn ...
Prado Wiliam A +3 more
doaj +1 more source
Cestodes are platyhelminth parasites with a wide range of hosts that cause neglected diseases. Neurotransmitter signaling is of critical importance for these parasites which lack circulatory, respiratory and digestive systems.
Federico Camicia +9 more
doaj +2 more sources
The Tricyclic Antidepressant Clomipramine Increases Plasma Glucose Levels of Mice
: Effects of the tricyclic antidepressant clomipramine on plasma glucose levels in mice were studied. Clomipramine at doses ranging 5 – 20 mg/kg elicited significant hyperglycemia in mice.
Yumi Sugimoto, Kiyo Inoue, Jun Yamada
doaj +1 more source
Paclitaxel, a primary chemotherapeutic agent used to treat numerous solid malignancies, is commonly associated with debilitating peripheral neuropathy. However, a satisfactory gold-standard monotherapy for this neuropathic pain is not currently available.
Daxian Li, Ju Hyuk Yoo, Sun Kwang Kim
doaj +1 more source
Tumor necrosis factor alpha induces a serotonin dependent early increase in ciliary beat frequency and epithelial transport velocity in murine tracheae. [PDF]
The tracheal epithelium prevents via its highly effective clearance mechanism the contamination of the lower airways by pathogens. This mechanism is driven by ciliary bearing cells which are not only in contact with the gas phase; in addition they are ...
Sebastian Weiterer +6 more
doaj +1 more source
PROSTAGLANDINS AND 5-HT RESPONSE ON GASTRIC SECRETION IN ALBINO RATS [PDF]
Prostaglandins (PGE1 ) 0.1, 0.2 and 0.4 mg/kg and 5-hydroxytryptamine (5-HT) 1, 2.5 and 5 mg/kg dose dependently inhibited gastric secretion in pyloric legated rats model While PGF2 ∝ 0.1, 0.4 and 1mg/kg inhibited gastric acid secretion. Methysergide
P.K. Debnath +4 more
doaj
Antinociceptive effect of chrysin in diabetic neuropathy and formalin-induced pain models
Chrysin, a natural flavonoid, is the main ingredient of many medicinal plants, which shows potent pharmacological properties. In the present study, the antinociceptive effects of chrysin were examined in ICR mice. Chrysin orally administered at the doses
Jae-Seung Hong +6 more
doaj +1 more source

