Results 31 to 40 of about 2,934 (153)

Mechanisms of Analgesic Action of Neurotropin on Chronic Pain in Adjuvant-Induced Arthritic Rat: Roles of Descending Noradrenergic and Serotonergic Systems

Journal of Pharmacological Sciences, 2005
Neurotropin®, a non-protein extract from the inflamed skin of rabbits inoculated with vaccinia virus, has been clinically used as an analgesic drug for treatment of chronic pain.
Tomoshi Miura, Ryohei Okazaki, Hiroyuki Yoshida, Hiroyoshi Namba, Hisashi Okai, Minoru Kawamura   +5 more
doaj   +1 more source

Effect of peripheral 5-HT on glucose and lipid metabolism in wether sheep. [PDF]

PLoS ONE, 2014
In mice, peripheral 5-HT induces an increase in the plasma concentrations of glucose, insulin and bile acids, and a decrease in plasma triglyceride, NEFA and cholesterol concentrations.
Hitoshi Watanabe, Ryo Saito, Tatsuya Nakano, Hideyuki Takahashi, Yu Takahashi, Keisuke Sumiyoshi, Katsuyoshi Sato, Xiangning Chen, Natsumi Okada, Shunsuke Iwasaki, Dian W Harjanti, Natsumi Sekiguchi, Hiroaki Sano, Haruki Kitazawa, Michael T Rose, Shyuichi Ohwada, Kouichi Watanabe, Hisashi Aso   +17 more
doaj   +1 more source

Involvement of serotonin and eicosanoids in the rat paw oedema response to the essential oil of Pilocarpus spicatus

Mediators of Inflammation, 1992
Subplantar injection of Pilocarpus spicatus essential oil (PSEO), induced rat hindpaw oedema in a dose-dependent manner. The time course study revealed that when compared to carrageenan-induced oedema, the oedema response to PSEO was greater at 1 h post ...
J. C. R. Silva, V. S. N. Rao
doaj   +1 more source

Pharmacological Characterization of Itch-Associated Response Induced by Repeated Application of Oxazolone in Mice

Journal of Pharmacological Sciences, 2010
We investigated pharmacological characteristics of the itch-associated response to chronic dermatitis induced by 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one (oxazolone) repeated application in mice.
Yukihito Tsukumo, Daisuke Harada, Haruhiko Manabe   +2 more
doaj   +1 more source

Inhibition Mechanism of Gosha-jinki-gan on the Micturition Reflex in Rats

Journal of Pharmacological Sciences, 2004
We investigated the actions of Gosha-jinki-gan, a traditional Japanese medicine containing processed Aconiti tubers, on urinary bladder function in anesthetized rats.
Akinobu Gotoh, Kazuhiro Goto, Atsushi Sengoku, Toshiro Shirakawa, Yoshinobu Akao, Masato Fujisawa, Hiroshi Okada, Soichi Arakawa, Sadao Kamidono   +8 more
doaj   +1 more source

New Approaches to Shifting the Migraine Treatment Paradigm

Frontiers in Pain Research, 2022
The standard of care paradigm for migraine treatment has been based almost exclusively on approaches that grew out of the happenstance use of market pharmaceuticals.
Brian Johnson, Frederick G. Freitag
doaj   +1 more source

Neurogenic mediators contribute to local edema induced by Micrurus lemniscatus venom. [PDF]

PLoS Neglected Tropical Diseases, 2017
Micrurus is one of the four snake genera of medical importance in Brazil. Coral snakes have a broad geographic distribution from the southern United States to Argentina.
Luciana Lyra Casais-E-Silva, Catarina Teixeira   +1 more
doaj   +1 more source

Neurotransmitter Mechanisms of Ketamine and Ketamine–Magnesium Sulfate-Induced Hypothermia: Evidence for Serotonergic and Adrenergic Involvement Without GABA_A Contributions

Brain Sciences
Background: Ketamine and magnesium sulfate are commonly used perioperatively to prevent shivering, a frequent and clinically relevant complication of spinal and general anesthesia.
Katarina Savić Vujović, Sonja Vučković, Lara Samardžić, Branislava Medić, Dragana Srebro, Ana Jotić, Ivana Ćirković   +6 more
doaj   +1 more source

Antinociceptive Effect of Shakuyakukanzoto, a Kampo Medicine, in Diabetic Mice

Journal of Pharmacological Sciences, 2005
In this study, the antinociceptive effect of shakuyakukanzoto was investigated using streptozotocin-induced diabetic mice to certify its analgesic effect on diabetic patients.
Yuji Omiya, Yasuyuki Suzuki, Mitsutoshi Yuzurihara, Mikio Murata, Masaki Aburada, Yoshio Kase, Shuichi Takeda   +6 more
doaj   +1 more source

Clinical Practice Guideline for Headache Disorders 2021

Neurology and Clinical Neuroscience, Volume 13, Issue 6, Page 389-407, November 2025.
ABSTRACT The International Headache Society published the International Classification of Headache Disorders, 3rd edition in 2018. In this classification, Chapter 3—previously “Cluster headache and other trigeminal‐autonomic cephalalgias”—was renamed “Trigeminal‐autonomic cephalalgias (TACs).” Trigeminal‐autonomic cephalalgias are a group of disorders ...
Nobuo Araki, Takao Takeshima, Hisaka Igarashi, Toshihiko Shimizu, Mamoru Shibata, Muneto Tatsumoto, Noboru Imai, Shoji Kikui, Tatsuo Iwashita, Daisuke Danno, on behalf of the Study Group for Headache Clinical Practice Guideline Development   +10 more
wiley   +1 more source