Results 131 to 140 of about 30,985 (250)

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

open access: yesPhotochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson   +6 more
wiley   +1 more source

Glyphosate residues in soil alter herbivore‐induced plant volatiles and affect predatory insect behaviour

open access: yesPlant Biology, EarlyView.
Herbicide residues in soil disrupt plant–insect signalling, reducing the effectiveness of biological pest control. Abstract Plants under herbivore attack emit distinct blends of herbivore‐induced plant volatiles (HIPVs) which serve as signalling cues for predatory insects.
B. Fuchs, J. D. Blande, V. Weijola
wiley   +1 more source

Two Novel and Three Recurrent Mutations in the Mevalonate Pathway Genes in Chinese Patients with Porokeratosis

open access: yes
Xiuping Wang,1 Xiaoliang Ouyang,2 Deng Zhang,1 Yunxia Zhu,1 Liang Wu,1 Zhen Xiao,3 Simin Yu,1 Wei Li,2 Chunming Li1 1Department of Dermatology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s Republic of China ...
Li W   +8 more
core  

Effect of phenyl and phenolic acids on mevalonate-5-Phosphate decarboxylase if the brain

open access: yes, 1979
Phenyl and phenolic acids are known to inhibit metabolism of mevalonate in rat brain. The site of inhibition has been found to be mevalonate-5-pyrophosphate decarboxylase. Phenolic acids also inhibited mevalonate-5-phosphate kinase on preincubation.
Ramasarma, T, Bhat, Charavu Shama
core   +1 more source

Metabolic reprogramming of the immune response in periodontitis

open access: yesPeriodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon   +3 more
wiley   +1 more source

Overall structure of homodimeric mevalonate-bound MmMK.

open access: yes, 2018
Protein is shown in cartoon, with monomers colored in violet and green, and mevalonate is shown in spheres.
Bradley R. Miller (6058193)   +1 more
core   +1 more source

Antiresorptive therapy influence on peri‐implant diseases: Clinical implications and osteoimmunological perspectives

open access: yesPeriodontology 2000, EarlyView.
Abstract Background/Aim Antiresorptive therapy represents a cornerstone in the management of osteoporosis and cancer‐related bone disease through suppression of osteoclast‐mediated bone resorption. As implant therapy becomes more common in aging populations, clinicians increasingly encounter patients receiving these medications, thus making their ...
Emilio A. Cafferata   +2 more
wiley   +1 more source

The inhibition of mevalonate pathway induces upregulation of NALP3 expression: new insight in the pathogenesis of mevalonate kinase deficiency.

open access: yes, 2010
Mevalonate kinase deficiency (MKD) is a rare hereditary auto-inflammatory syndrome due to mutations in mevalonate kinase, the second enzyme of mevalonate pathway of cholesterol, and nonsterol-isoprenoids biosynthesis.
A. Pontillo   +7 more
core   +1 more source

Nitrogen‐Based Bisphosphonate Use and Risk of Cancer in Women Aged 50 Years and Older: A National Data Linkage Study

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1669-1685, 1 October 2026.
Bisphosphonates are widely used to treat osteoporosis and to manage bone metastases in patients with breast cancer. Nitrogen‐based bisphosphonates may also broadly reduce cancer risk, but evidence remains inconsistent. This large population‐based data linkage study in women aged > 50 years found that, compared to no use of osteoporosis medicines ...
Karen M. Tuesley   +7 more
wiley   +1 more source

Exploring the Impact of Urolithins A and B on Muscle Health: A Transcriptomic Analysis in Human Myotubes

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Urolithin A (UA) and urolithin B (UB) are gut microbiota‐derived metabolites of ellagitannins reported to influence mitochondrial function, inflammation and muscle metabolism. Their comparative transcriptomic effects in human skeletal muscle cells remain undefined.
Yves Henrotin   +8 more
wiley   +1 more source

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