Results 111 to 120 of about 24,078 (213)

Mevalonate in blood and muscle: Response to atorvastatin treatment and the relationship to statin intolerance in patients with coronary heart disease

Clinical and Translational Science
Statin‐associated muscle symptoms are frequently reported and often lead to discontinuation of statin therapy with an increased risk of cardiovascular events.
Trine Lauritzen, John Munkhaugen, Stein Bergan, Elise Sverre, Kari Peersen, Sofia Lindahl, Einar Husebye, Nils Tore Vethe   +7 more
doaj   +1 more source

Mevalonate pathway activation in Ewing sarcoma reveals a 3D-specific synergy between statins and BCL-xL inhibition. [PDF]

Mol Ther Oncol
Radic-Sarikas B, Markovic M, Zylka MM, Sturtzel C, Ilg M, Surdez D, Metzelder M, Distel M, Ovsianikov A, Halbritter F, Kovar H.   +10 more
europepmc   +2 more sources

Targeting the mevalonate pathway with statins overcomes acquired resistance to KRAS^G12C inhibitors in non-small cell lung cancer. [PDF]

Exp Hematol Oncol
Lin W, Chen QA, Yang Y, Gao Y, He J.
europepmc   +1 more source

Lipophilic Statins Deplete GPX4 to Promote Ferroptosis and Sensitize Cancer Cells to Immune Checkpoint Blockade. [PDF]

Mol Cancer Ther
Talty R, Brooks VT, McGeary MK, Milette S, Zheng S, Flem-Karlsen K, Daniels A, Deshmukh M, Park K, Caraccio W, Yan H, Echeandia-Francis C, McNamara M, Hong S, Kirwin DS, Olino K, Johnson CH, Bosenberg M, Micevic G, Roy SF.   +19 more
europepmc   +1 more source

<i>De novo</i> production of (-)-limonene, (-)-carveol and (-)-carvone via engineering <i>Rhodotorula toruloides</i>. [PDF]

Synth Syst Biotechnol
Dong Y, Cui S, Du B, Zhang X, Hou J, Lin X, Qin Y, Wang X, Yang X.   +8 more
europepmc   +1 more source

A Diagnostic Odyssey: Mevalonate Kinase Deficiency Revealed by Genetic Testing in Adulthood. [PDF]

Genes (Basel)
Kumar V, de Saint-Aubain CJ, Konstantinov KN.   +2 more
europepmc   +1 more source

Mitochondria limit coenzyme Q export under cholesterol biosynthetic stress. [PDF]

J Cell Biol
Ndoci M, Bhattacharya S, Agrawal I, Hinze Y, Lemke K, Schumacher AL, Uijttewaal E, Elling U, Lawo S, Giavalisco P, Langer T, Deshwal S.   +11 more
europepmc   +1 more source

Mevalonic aciduria [PDF]

, 2020
openaire   +2 more sources

Beyond barrier function: keratinocytes as orchestrators of humoral immunity. [PDF]

Immun Inflamm
Guo C, Tsokos GC.
europepmc   +1 more source

Reprogramming lipid metabolism in pediatric cancers. [PDF]

Oncogenesis
Lindemann VL, Noureddine N, Morscher RJ.
europepmc   +1 more source