Results 141 to 150 of about 21,930 (203)

Activity-based probes and chemical proteomics uncover the biological impact of targeting HMG-CoA Synthase 1 in the mevalonate pathway. [PDF]

J Biol Chem
Yi SA, Sun L, Rao Y, Ordureau A, Lewis JS, An H.   +5 more
europepmc   +1 more source

Targeting the mevalonate pathway enhances the efficacy of 5-fluorouracil by regulating pyroptosis. [PDF]

Med Oncol
Xing Z, Ma Y, Jiang X, Qing H, Wu Y, Che S, Gao Z, Wang K, Wang T, He Q, Li Z, Zhao B, Liu W, Sun H, Yu Z.   +14 more
europepmc   +1 more source

Reconstitution of the Mevalonate Pathway for Improvement of Isoprenoid Production and Industrial Applicability in Escherichia coli. [PDF]

J Microbiol Biotechnol
Kang MK, Nguyen MP, Yoon SH, Jayasundera KB, Son JW, Wang C, Kwon M, Kim SW.   +7 more
europepmc   +1 more source

Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity. [PDF]

Cell Rep Med
Gui L, Chen K, Yan J, Chen P, Gao WQ, Ma B.   +5 more
europepmc   +1 more source

Synthetic inhibition of SREBP2 and the mevalonate pathway blocks rhabdomyosarcoma tumor growth in vitro and in vivo and promotes chemosensitization. [PDF]

Mol Metab
Codenotti S, Asperti M, Poli M, Lorenzi L, Pietrantoni A, Cassandri M, Marampon F, Fanzani A.   +7 more
europepmc   +1 more source

Archaeal mevalonate pathway in the uncultured bacterium Candidatus Promineifilum breve belonging to the phylum Chloroflexota. [PDF]

Appl Environ Microbiol
Kanno K, Kuriki R, Yasuno Y, Shinada T, Ito T, Hemmi H.   +5 more
europepmc   +1 more source

Induction of resistance to neurotrophic tropomyosin-receptor kinase inhibitors by HMGCS2 via a mevalonate pathway. [PDF]

Cancer Med
Kato Y, Matsumoto M, Takano N, Hirao M, Matsuda K, Tozuka T, Onda N, Nakamichi S, Takeuchi S, Miyanaga A, Noro R, Gemma A, Seike M.   +12 more
europepmc   +1 more source

Mevalonate pathway inhibition reduces bladder cancer metastasis by modulating RhoB protein stability and integrin β1 localization. [PDF]

Commun Biol
Wang G, Peng T, Chen L, Xiong K, Ju L, Qian K, Zhang Y, Xiao Y, Wang X.   +8 more
europepmc   +1 more source

Pitavastatin induces autophagy-dependent ferroptosis in MDA-MB-231 cells via the mevalonate pathway. [PDF]

Heliyon
Tang WJ, Xu D, Liang MX, Wo GQ, Chen WQ, Tang JH, Zhang W.   +6 more
europepmc   +1 more source

The non-mevalonate pathway requires a delicate balance of intermediates to maximize terpene production. [PDF]

Appl Microbiol Biotechnol
Raghavan I, Juman R, Wang ZQ.
europepmc   +1 more source