Results 131 to 140 of about 22,865 (199)

Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling. [PDF]

Proc Natl Acad Sci U S A
Guzman A, Kawase T, Devanny AJ, Efe G, Navaridas R, Yu K, Regunath K, Mercer IG, Avard RC, Muniz de Queiroz R, Rustgi AK, Kaufman LJ, Prives C.   +12 more
europepmc   +1 more source

Mevalonate pathway-triggered phase transition of injectable hydrogel for cholesterol-downregulated therapy of osteoarthritis. [PDF]

Bioact Mater
Robby AI, Kim EH, Huh KM, Jin EJ, Park KD, Park SY.   +5 more
europepmc   +1 more source

Marine <i>Flavobacteriaceae</i> produce zeaxanthin via the mevalonate pathway. [PDF]

Mar Life Sci Technol
Chen Y, Xie J, Yang M, Cai R, Cai C, Gan Y, Aweya JJ, Cai G, Wang H.   +8 more
europepmc   +1 more source

Regulation of glial ApoE secretion by the mevalonate pathway is independent of ApoE isoform. [PDF]

J Alzheimers Dis
Milstein JL, Kulas JA, Kamal A, Lo AB, Ferris HA.   +4 more
europepmc   +1 more source

An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma. [PDF]

J Clin Invest
Holm A, Graus MS, Wylie-Sears J, Tan JWH, Alvarez-Harmon M, Borgelt L, Nasim S, Chung L, Jain A, Sun M, Sun L, Brouillard P, Lekwuttikarn R, Qi Y, Teng J, Vikkula M, Kozakewich H, Mulliken JB, Francois M, Bischoff J.   +19 more
europepmc   +1 more source

Activity-based probes and chemical proteomics uncover the biological impact of targeting HMG-CoA Synthase 1 in the mevalonate pathway. [PDF]

J Biol Chem
Yi SA, Sun L, Rao Y, Ordureau A, Lewis JS, An H.   +5 more
europepmc   +1 more source

Targeting the mevalonate pathway enhances the efficacy of 5-fluorouracil by regulating pyroptosis. [PDF]

Med Oncol
Xing Z, Ma Y, Jiang X, Qing H, Wu Y, Che S, Gao Z, Wang K, Wang T, He Q, Li Z, Zhao B, Liu W, Sun H, Yu Z.   +14 more
europepmc   +1 more source

Reconstitution of the Mevalonate Pathway for Improvement of Isoprenoid Production and Industrial Applicability in Escherichia coli. [PDF]

J Microbiol Biotechnol
Kang MK, Nguyen MP, Yoon SH, Jayasundera KB, Son JW, Wang C, Kwon M, Kim SW.   +7 more
europepmc   +1 more source

Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity. [PDF]

Cell Rep Med
Gui L, Chen K, Yan J, Chen P, Gao WQ, Ma B.   +5 more
europepmc   +1 more source

Synthetic inhibition of SREBP2 and the mevalonate pathway blocks rhabdomyosarcoma tumor growth in vitro and in vivo and promotes chemosensitization. [PDF]

Mol Metab
Codenotti S, Asperti M, Poli M, Lorenzi L, Pietrantoni A, Cassandri M, Marampon F, Fanzani A.   +7 more
europepmc   +1 more source