Results 131 to 140 of about 21,930 (203)

Thermostable Enzyme Variants in the Lower Mevalonate Pathway Improve Isoprenoid Production by Cell-Free Biocatalysis. [PDF]

ACS Sustain Chem Eng
Sarnik SA, Martinsen MR, Korman TP, Schwartz DK, Kaar JL, Bomble YJ.   +5 more
europepmc   +1 more source

Antidiabetic drug metformin suppresses tumorigenesis through inhibition of mevalonate pathway enzyme HMGCS1. [PDF]

J Biol Chem, 2022
Chen Y, Li M, Yang Y, Lu Y, Li X.
europepmc   +1 more source

Cholesterol-Lowering Phytochemicals: Targeting the Mevalonate Pathway for Anticancer Interventions. [PDF]

Front Genet, 2022
Laka K, Makgoo L, Mbita Z.
europepmc   +1 more source

Antibiotic-free high-yield (-)-α-bisabolol production in <i>Serratia marcescens</i> via metabolic engineering and genomic integration of mevalonate pathway genes. [PDF]

Synth Syst Biotechnol
Li W, Liu D, Gou L, Wu S, Zhou X, Fan TP, Wang L, Cai Y.   +7 more
europepmc   +1 more source

Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition. [PDF]

Immunology
Suen TK, Al B, Ulas T, Reusch N, Bahrar H, Bekkering S, Bhat J, Kabelitz D, Schultze JL, van de Veerdonk FL, van Lennep JR, Riksen NP, Joosten LAB, Netea MG, Placek K.   +14 more
europepmc   +1 more source

Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling. [PDF]

Proc Natl Acad Sci U S A
Guzman A, Kawase T, Devanny AJ, Efe G, Navaridas R, Yu K, Regunath K, Mercer IG, Avard RC, Muniz de Queiroz R, Rustgi AK, Kaufman LJ, Prives C.   +12 more
europepmc   +1 more source

Mevalonate pathway-triggered phase transition of injectable hydrogel for cholesterol-downregulated therapy of osteoarthritis. [PDF]

Bioact Mater
Robby AI, Kim EH, Huh KM, Jin EJ, Park KD, Park SY.   +5 more
europepmc   +1 more source

Marine <i>Flavobacteriaceae</i> produce zeaxanthin via the mevalonate pathway. [PDF]

Mar Life Sci Technol
Chen Y, Xie J, Yang M, Cai R, Cai C, Gan Y, Aweya JJ, Cai G, Wang H.   +8 more
europepmc   +1 more source

Regulation of glial ApoE secretion by the mevalonate pathway is independent of ApoE isoform. [PDF]

J Alzheimers Dis
Milstein JL, Kulas JA, Kamal A, Lo AB, Ferris HA.   +4 more
europepmc   +1 more source

An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma. [PDF]

J Clin Invest
Holm A, Graus MS, Wylie-Sears J, Tan JWH, Alvarez-Harmon M, Borgelt L, Nasim S, Chung L, Jain A, Sun M, Sun L, Brouillard P, Lekwuttikarn R, Qi Y, Teng J, Vikkula M, Kozakewich H, Mulliken JB, Francois M, Bischoff J.   +19 more
europepmc   +1 more source