Results 111 to 120 of about 5,468 (165)

The impact of lipid-rich nutrition on ketogenesis and muscle weakness in sepsis. [PDF]

Intensive Care Med Exp
Lauwers C, Gunst J, El Dawy S, Derde S, Pauwels L, Derese I, Vander Perre S, Van den Berghe G, Casaer MP, Langouche L.   +9 more
europepmc   +1 more source

Multi-Omics Analysis Unravels the Biosynthesis and Regulatory Mechanisms of Floral Scent Across Various Cultivars and Developmental Stages in <i>Phalaenopsis</i>. [PDF]

Plants (Basel)
Zhong H, Chen Y, Zhong S, He J, Lin B, Wu J, Fan R.   +6 more
europepmc   +1 more source

Behçet's Disease: A Comprehensive Overview of Symptoms, Pathology, Genetics, and Treatment. [PDF]

J Mother Child
Batalli A, Liehr T, Temaj G.
europepmc   +1 more source

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Occurrence of Mevalonic Acid in Carrots

Nature, 1961
ALTHOUGH tracer studies in a number of carotenogenic systems1,2 have conclusively proved that mevalonic acid is an effective precursor of carotenes, the presence of mevalonic acid has not been demonstrated in any of such systems. In this laboratory an attempt has been made to isolate mevalonic acid from carrots.
V V, MODI, D K, PATWA
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Stereospecificity of Enzymic Reactions involving Mevalonic Acid

Nature, 1960
MOST of the biosynthetic studies with mevalonic acid have so far been carried out with the racemic substance labelled with carbon-14. There have been no reports indicating a utilization greater than 50 per cent of DL-mevalonate either in vivo or in vitro in any enzymic reaction.
R H, CORNFORTH, K, FLETCHER, H, HELLIG, G, POPJAK   +3 more
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Determination of mevalonic acid in human urine as mevalonic acid lactone by gas chromatography–mass spectrometry

Journal of Chromatography B: Biomedical Sciences and Applications, 2001
Mevalonic acid in urine is converted to its lactone form by incubation overnight at acidic pH, extracted and analysed by GC-MS. The lower limit of quantitation of 7.5 ng/ml provides adequate sensitivity to measure changes in urinary excretion of MVA following administration of drugs which affect cholesterol synthesis.
B H, Woollen, P C, Holme, W J, Northway, P D, Martin   +3 more
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Mevalonates Restore Zoledronic Acid–induced Osteoclastogenesis Inhibition

Journal of Dental Research, 2014
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is likely to be caused by continuous imperfection of bone healing after surgical treatments in patients with long-term administration of nitrogen-containing bisphosphonates (NBPs). NBPs inhibit osteoclastic bone resorption by impairing the mevalonic acid sterol pathway in osteoclasts.
Y, Nagaoka, H, Kajiya, S, Ozeki, T, Ikebe, K, Okabe   +4 more
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Mevalonic Acid Analogs as Inhibitors of Cholesterol Biosynthesis

Journal of Pharmaceutical Sciences, 1981
A series of 20 mevalonic acid analogs was synthesized and tested for their ability to inhibit cholesterol biosynthesis from [2-14C]-mevalonate in rat liver homogenates. Removal of the 5-hydroxyl group from mevalonic acid produced an active inhibitor, 3-hydroxy-3-methylpentanoic acid. Removal of the 3-hydroxyl group, addition of an aromatic group in the
C R, DeBold, J C, Elwood
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