Results 91 to 100 of about 562 (137)

A comparative study of mexidol and mexiprim pharmacokinetic parameters

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2014
Objective. To compare pharmacokinetic parameters of mexidol (coated tablets, "Farmasoft") and mexiprim (tablets film-coated, "STADA CIS"). Material and methods. The study included 14 adult male Chinchilla rabbits. Concentration of 2-ethyl-6-methyl-3-hydroxypyridine succinate in the blood plasma of animals was analyzed using HPLC with UV detection ...
A V, Shchul'kin, E N, Iakusheva, I V, Chernykh   +2 more
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The cerebroprotective effects of Mexidol in patients with hypertension

S.S. Korsakov Journal of Neurology and Psychiatry
Hypertension remains a leading cause of cardiovascular morbidity, mortality, and disability worldwide. It is also a significant modifiable factor contributing to chronic brain damage. Key mechanisms involved in this process include cerebral microangiopathy, endothelial dysfunction, impaired autoregulation of cerebral blood flow, and oxidative stress ...
S.A. Dreshina, S.N. Yanishevsky
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Mexidol in the rehabilitation of patients in the acute ischemic stroke

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2015
Research objective - studying of results of a comprehensive neuro-rehabilitation patients in the acute ischemic stroke (according to the Samara regional vascular centre).A review of the work of RVC on the main indicators for 2014, detailed analysis of 20 patients in the acute period of ischemic stroke, in which treatment was used the drug mexidol with ...
O V, Androfagina, T V, Kuznetsova, A A, Svetkina   +2 more
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Possibilities of using Mexidol in the complex therapy of mental disorders

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2020
A review of the current literature on the possible use of mexidol (ethylmethylhydroxypyridine succinate) in the treatment of mental (including addictive) disorders is conducted. The possibility of its use to reduce negative psychopathological symptoms, neurocognitive deficit, manifestations of the antipsychotic syndrome (including its extrapyramidal ...
V K, Shamrey, E S, Kurasov, V V, Nechiporenko, A I, Kolchev, N V, Tsygan   +4 more
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Mnemotropic and anxiolytic activity of mexidol and enoxifol

Journal of New Medical Technologies. eJournal, 2015
The article presents the research findings of influence of antioxidant compounds Enoxifol (10 mg/kg) and Mexidol (100 mg/kg) on behavior, emotional sphere and ability for self-regulation of experimental animals. The mechanism of Enoxifol and Mexidol action at high nervous functions was established on the basis of tests allowing to ...
I. Tregubova, null Трегубова
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A modern concept of antihypoxic and antioxidant effects of mexidol

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2018
The review article presents a modern concept of the mechanism of antioxidant and antihypoxic action of the original drug mexidol (2-ethyl-6-methyl-3-hydroxypyridine succinate). The direct antioxidant activity of mexidol has been described, which consists in the ability of the drug to inactivate free radicals and increase the activity of the antioxidant
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Improvement of the efficacy of treatment of hypertensive encephalohathy by using mexidol

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2018
To assess the efficacy and tolerability of mexidol used to improve cognitive impairment in patients with hypertension and clinical manifestations of chronic cerebral circulatory insufficiency.Forty-two patients with chronic cerebral circulatory insufficiency and cognitive impairment were examined.
E V, Bolotova, N Yu, Lushpay, I V, Kovrigina   +2 more
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[The effects of mexidol in pain syndromes].

Eksperimental'naia i klinicheskaia farmakologiia, 1995
Models of neuropathic pain syndrome and adjuvant arthritis were used to study the effect of mexidole, an antioxidant from the 3-hydroxypyridine group. Mexidole was indicated to produce no preventive effect in pain syndromes, but to exhibit a therapeutic one.
E D, Danilova, V N, Grafova, T A, Voronina, V K, Reshetniak   +3 more
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Preventive therapy with mexidol in toxic damage to the heart

Khirurgiya. Zhurnal im. N.I. Pirogova, 2018
The purpose of this study was to efficacy of mexidol in the prevention of toxic damage to the heart in acute pancreatitis.The paper presents the results of experimental studies conducted on 30 adult mongrel adult dogs, which simulated acute focal pancreatic necrosis.
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Cerebroprotective Effects of Emoxipin, Reamberin, and Mexidol in Alloxan Diabetes

Bulletin of Experimental Biology and Medicine, 2013
The effects of original Russian preparations, derivatives of 3-hydroxypyridine and succinic acid (emoxipin, reamberin, mexidol), on the cellular composition of the cerebrocortical and diencephalic structures were studied and correlations of shifts in the cellular composition with changes in the severity of hyperglycemia in rats with alloxan diabetes ...
I A, Volchegorskii, L M, Rassokhina, I Yu, Miroshnichenko   +2 more
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