PLoS ONE, 2012 The immunogenicity and the efficacy of a beta-propiolactone-inactivated caprine herpesvirus 1 (CpHV-1) vaccine adjuvanted with MF59™ were tested in goats.
Mariarosaria Marinaro +8 more
doaj +2 more sources
PLoS MedicineBackgroundAdjuvants are widely used to enhance and/or direct vaccine-induced immune responses yet rarely evaluated head-to-head. Our trial directly compared immune responses elicited by MF59 versus alum adjuvants in the RV144-like HIV vaccine regimen ...
Zoe Moodie +33 more
doaj +2 more sources
From injection to inhalation: A STING-activating mucosal adjuvant reprograms vaccination. [PDF]
Clin Transl MedClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Wang W, Wang M, Lu L, Jiang S, Liu Z.
europepmc +2 more sources
Development of a Trivalent Seasonal Influenza Vaccine Using Long α-Helix-Mediated Trimeric HA1 Proteins Produced in Baculovirus-Insect Cell System. [PDF]
MedComm (2020)MedComm, Volume 7, Issue 8, August 2026.
Guo N +6 more
europepmc +2 more sources
Identification of Mannose-Capped-Arabinomannan 101-mer as a Potential Influenza Virus Vaccine Adjuvant. [PDF]
Adv Sci (Weinh)Well‐defined and synthetic mannose‐capped arabinomannan 101‐mer from Mycobacterium tuberculosis cell wall was identified as a potent influenza vaccine adjuvant, boosting the antibody response, realizing full protection and showing excellent safety. ABSTRACT Many natural bacterial components as adjuvants can activate the host immune system, but the ...
Zhang YF +5 more
europepmc +2 more sources
Immunopotentiation by Natural Extracts: Mechanisms and Applications in Influenza Vaccine Adjuvant Development. [PDF]
Food Sci NutrNatural Extracts as Candidate Influenza Vaccine Adjuvants. Seasonal influenza vaccines face limitations due to viral mutations and low efficacy in vulnerable populations. Traditional adjuvants often have safety or immune‐activation constraints, leading to increased interest in natural extracts from plants, marine organisms, and fungi.
Ho TL, Ko EJ.
europepmc +2 more sources
Viruses, 2022 Swine influenza virus (SIV) circulates worldwide, posing substantial economic loss and disease burden to humans and animals. Vaccination remains the most effective way to prevent SIV infection and transmission.
Pan Tang +6 more
doaj +1 more source
Altered response to A(H1N1)pnd09 vaccination in pregnant women: a single blinded randomized controlled trial. [PDF]
PLoS ONE, 2013 Pregnant women were suspected to be at particular risk when H1N1pnd09 influenza became pandemic in 2009. Our primary objective was to compare the immune responses conferred by MF59®-adjuvanted vaccine (Focetria®) in H1N1pnd09-naïve pregnant and non ...
Anne Louise Bischoff +9 more
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Adjuvantation of Influenza Vaccines to Induce Cross-Protective Immunity
Vaccines, 2021 Influenza poses a huge threat to global public health. Influenza vaccines are the most effective and cost-effective means to control influenza. Current influenza vaccines mainly induce neutralizing antibodies against highly variable globular head of ...
Zhuofan Li +3 more
doaj +1 more source
Comparative Study on the Efficacy of MF 59, ISA70 VG, and Nano-Aluminum Hydroxide Adjuvants, Alone and with Nano-Selenium on Humoral Immunity Induced by a Bivalent Newcastle+Avian Influenza Vaccine in Chickens [PDF]
Archives of Razi Institute, 2021 Newcastle disease (ND) and Avian influenza (AI) are the major problems and the most economically important viral diseases in the poultry industry; therefore, vaccination against these diseases is considered one of the most effective ways of prevention ...
M Radmehri +5 more
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