Results 51 to 60 of about 5,863 (219)

The Immunogenicity of CpG, MF59-like, and Alum Adjuvant Delta Strain Inactivated SARS-CoV-2 Vaccines in Mice

Vaccines
The continuous evolution and mutation of SARS-CoV-2 have highlighted the need for more effective vaccines. In this study, CpG, MF59-like, and Alum adjuvant Delta strain inactivated SARS-CoV-2 vaccines were prepared, and the immunogenicity of these ...
Kangwei Xu, Jing Li, Xu Lu, Xiaoqin Ge, Kaiqin Wang, Jiahao Wang, Zhizhong Qiao, Yaru Quan, Changgui Li   +8 more
doaj   +1 more source

Intranasal Immunization Using Mannatide as a Novel Adjuvant for an Inactivated Influenza Vaccine and Its Adjuvant Effect Compared with MF59.

PLoS ONE, 2017
Intranasal vaccination is more potent than parenteral injection for the prevention of influenza. However, because the poor efficiency of antigen uptake across the nasal mucosa is a key issue, immunostimulatory adjuvants are essential for intranasal ...
Shu-Ting Ren, Xue-Mei Zhang, Peng-Fei Sun, Li-Juan Sun, Xue Guo, Tian Tian, Jian Zhang, Qi-Yuan Guo, Xue Li, Li-Jun Guo, Jin Che, Bing Wang, Hui Zhang   +12 more
doaj   +1 more source

Adjuvants in vaccines registered for human use [PDF]

Arhiv za farmaciju, 2019
Vaccination is one of the most efficient strategies for prevention of infection diseases, but with introduction of sub-unit vaccines with lower immunogenicity adjuvants were needed to enhance the immune response.
Filipić Brankica, Stojić-Vukanić Zorica   +1 more
doaj   +1 more source

Respiratory Syncytial Virus F Subunit Vaccine With AS02 Adjuvant Elicits Balanced, Robust Humoral and Cellular Immunity in BALB/c Mice

Frontiers in Immunology, 2020
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory illness, particularly in infants, the elderly, and immunocompromised adults. There is no licensed commercial vaccine against RSV.
Yu Zheng, Lijun Bian, Huiting Zhao, Yulan Liu, Jingcai Lu, Jingcai Lu, Dawei Liu, Dawei Liu, Ke Zhang, Yueshuang Song, Yueshuang Song, Yusi Luo, Chunlai Jiang, Chunlai Jiang, Yan Chen, Yan Chen, Yong Zhang, Yong Zhang, Wei Kong, Wei Kong   +19 more
doaj   +1 more source

Principales sistemas de entrega de antígenos en Medicina Veterinaria y Humana [PDF]

, 2014
Las vacunas modernas se basan generalmente en proteínas recombinantes altamente purificadas. Esta alta pureza representa uno de los mayores avances en términos de seguridad, en comparación a las estrategias de vacunación tradicionales basadas en ...
Siel, Daniela, Sáenz, Leonardo, Vidal, Sonia   +2 more
core   +2 more sources

A Prussian Blue Nanozyme‐Adjuvanted Vaccine Presenting Phosphocholine Antigens for Induction of Immunotolerance in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study developed a novel nano‐vaccine (Ferritin‐PC@PBNZs) comprising a ferritin‐based scaffold for the multivalent display of phosphorylcholine (PC) antigens, integrated with Prussian blue nanozymes (PBNZs) as a potent adjuvant. By leveraging the ferritin carrier for high‐density and ordered antigen display, the nano‐vaccine significantly augments ...
Jingyi Sheng, Yubo Huang, Xinyue Li, Yin Liu, Yuehuang Wu, Yuxin Zhang, Ning Gu   +6 more
wiley   +1 more source

Safety of pandemic (H1N1) 2009 monovalent vaccines in taiwan: a self-controlled case series study.

PLoS ONE, 2013
In Taiwan, new H1N1 monovalent vaccines without adjuvant and with MF59® adjuvant were used in the nationwide vaccination campaign beginning on November 1, 2009.
Wan-Ting Huang, Hsu-Wen Yang, Tzu-Lin Liao, Wan-Jen Wu, Shu-Er Yang, Yi-Chien Chih, Jen-Hsiang Chuang   +6 more
doaj   +1 more source

Safety and immunogenicity of an MF59™-adjuvanted subunit influenza vaccine in elderly Chinese subjects [PDF]

, 2008
BACKGROUND: The safety and immunogenicity of an MF59™-adjuvanted subunit influenza vaccine (Sub/MF59™; FLUAD(®), Novartis Vaccines) was evaluated among elderly Chinese subjects (≥ 60 years of age).
Audino Podda, Hanhua Fang, Michele Pellegrini, Rongcheng Li, Yanping Li, Youping Liu   +5 more
core   +2 more sources

MF59-adjuvanted vaccines: increased immunogenicity with an optimal safety profile

Expert Review of Vaccines, 2003
The need to enhance the immunogenicity of purified subunit antigens has prompted the development of several new adjuvants. However, many of these new molecules have demonstrated a reactogenicity profile that is not suitable for their inclusion in vaccines for human use.
Audino, Podda, Giuseppe, Del Giudice
openaire   +2 more sources

Hydroxypropyl Cellulose Enhances Immune Responses to the Current Seasonal Influenza Vaccine in Mice

Microbiology and Immunology, Volume 70, Issue 2, Page 68-79, February 2026.
ABSTRACT Influenza A and B viruses cause annual epidemics and continue to pose global public health concerns. The most effective approach to preventing or mitigating the severity of influenza is vaccination. Inactivated split influenza HA vaccines are commonly used worldwide due to their strong safety profile and broad range of target groups; however ...
Nantaporn Kaewaroon, Sara Yoshimoto, Luthfi Muawan, Shintaro Shichinohe, Tokiko Watanabe   +4 more
wiley   +1 more source