Results 81 to 90 of about 5,863 (219)

Differential Immunogenicity and Protective Efficacy Elicited by MTO- and DMT-Adjuvanted CMFO Subunit Vaccines against Mycobacterium tuberculosis Infection

open access: yesJournal of Immunology Research, 2020
Tuberculosis (TB) remains a major and global problem of public health. An effective TB subunit vaccine is urgently needed. Proper selection of the delivery system for the vaccine is crucial for inducing an appropriate immune response tailored to control ...
Nadeem Ullah   +7 more
doaj   +1 more source

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]

open access: yes, 2014
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow   +30 more
core   +3 more sources

Safety and Immunogenicity of Nonadjuvanted and MF59-Adjuvanted Influenza A/H9N2 Vaccine Preparations [PDF]

open access: yesClinical Infectious Diseases, 2006
Influenza A/H9N2 viruses can infect humans and are considered to be a pandemic threat. Effective vaccines are needed for these and other avian influenza viruses.We performed a phase I, randomized, double-blind trial to evaluate the safety and immunogenicity of a 2-dose schedule (administered on days 0 and 28) of 4 dose levels (3.75, 7.5, 15, and 30 ...
Robert L, Atmar   +8 more
openaire   +2 more sources

Current Progress in Targeting Human Cytomegalovirus Infection

open access: yesiLABMED, Volume 3, Issue 3, Page 303-311, September 2025.
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley   +1 more source

Formulation of hepatitis B vaccine in MF59 adjuvant and comparison of its immunization with Iran\'s commercial hepatitis B vaccine

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2018
Introduction: Hepatitis is a systemic diseasethat causes liver inflammation. The prevention of this infection is a vaccination. The commonly used vaccine to fight this disease is to use the vaccine formulated with Alum. This vaccine cannot provide immune
Reyhaneh Mirzaei   +2 more
doaj  

Comprehensive Analysis of the Safety Profile of a Single-Stranded RNA Nano-Structure Adjuvant

open access: yesPharmaceutics, 2019
Adjuvants enhance the efficacy of vaccines by stimulating immune response-related gene expression and pathways. Although some adjuvants have been approved for commercial use in human vaccines (e.g., Alum, MF59, and AS03), they might elicit adverse side ...
Hyeong-Jun Park   +8 more
doaj   +1 more source

Adjuvants : an essential component of neisseria vaccines [PDF]

open access: yes, 2009
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R.   +8 more
core  

Microneedle delivery systems for vaccines and immunotherapy

open access: yesSmart Molecules, Volume 3, Issue 3, September 2025.
This paper reviews the preparation methods and materials of microneedles for drug delivery, summarizes the structures and types of microneedle systems, analyzes the influence of antigens and adjuvants on the efficacy of microneedle vaccines, and reviews the current application status of microneedles in the fields of vaccines and immunotherapy by ...
Haiyao Jia   +5 more
wiley   +1 more source

Impacto económico y sanitario de la utilización de vacuna antigripal adyuvada con MF59 en población mayor de 65 años en España [PDF]

open access: yes, 2019
La gripe es un importante problema de salud, tanto por la mortalidad que puede provocar directa o indirectamente como por las complicaciones que ocasiona y los costes económicos y sociales que origina.
Rodríguez Márquez, Carlos   +1 more
core  

Beyond antigens and adjuvants: formulating future vaccines [PDF]

open access: yes, 2016
The need to optimize vaccine potency while minimizing toxicity in healthy recipients has motivated studies of the formulation of vaccines to control how, when, and where antigens and adjuvants encounter immune cells and other cells/tissues following ...
Ali   +16 more
core   +1 more source

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