Results 81 to 90 of about 5,863 (219)
Tuberculosis (TB) remains a major and global problem of public health. An effective TB subunit vaccine is urgently needed. Proper selection of the delivery system for the vaccine is crucial for inducing an appropriate immune response tailored to control ...
Nadeem Ullah +7 more
doaj +1 more source
Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow +30 more
core +3 more sources
Safety and Immunogenicity of Nonadjuvanted and MF59-Adjuvanted Influenza A/H9N2 Vaccine Preparations [PDF]
Influenza A/H9N2 viruses can infect humans and are considered to be a pandemic threat. Effective vaccines are needed for these and other avian influenza viruses.We performed a phase I, randomized, double-blind trial to evaluate the safety and immunogenicity of a 2-dose schedule (administered on days 0 and 28) of 4 dose levels (3.75, 7.5, 15, and 30 ...
Robert L, Atmar +8 more
openaire +2 more sources
Current Progress in Targeting Human Cytomegalovirus Infection
This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley +1 more source
Introduction: Hepatitis is a systemic diseasethat causes liver inflammation. The prevention of this infection is a vaccination. The commonly used vaccine to fight this disease is to use the vaccine formulated with Alum. This vaccine cannot provide immune
Reyhaneh Mirzaei +2 more
doaj
Comprehensive Analysis of the Safety Profile of a Single-Stranded RNA Nano-Structure Adjuvant
Adjuvants enhance the efficacy of vaccines by stimulating immune response-related gene expression and pathways. Although some adjuvants have been approved for commercial use in human vaccines (e.g., Alum, MF59, and AS03), they might elicit adverse side ...
Hyeong-Jun Park +8 more
doaj +1 more source
Adjuvants : an essential component of neisseria vaccines [PDF]
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R. +8 more
core
Microneedle delivery systems for vaccines and immunotherapy
This paper reviews the preparation methods and materials of microneedles for drug delivery, summarizes the structures and types of microneedle systems, analyzes the influence of antigens and adjuvants on the efficacy of microneedle vaccines, and reviews the current application status of microneedles in the fields of vaccines and immunotherapy by ...
Haiyao Jia +5 more
wiley +1 more source
Impacto económico y sanitario de la utilización de vacuna antigripal adyuvada con MF59 en población mayor de 65 años en España [PDF]
La gripe es un importante problema de salud, tanto por la mortalidad que puede provocar directa o indirectamente como por las complicaciones que ocasiona y los costes económicos y sociales que origina.
Rodríguez Márquez, Carlos +1 more
core
Beyond antigens and adjuvants: formulating future vaccines [PDF]
The need to optimize vaccine potency while minimizing toxicity in healthy recipients has motivated studies of the formulation of vaccines to control how, when, and where antigens and adjuvants encounter immune cells and other cells/tissues following ...
Ali +16 more
core +1 more source

