Results 51 to 60 of about 1,598 (170)
HP-induced increased latent MHV68 infection is dependent on vitamin A.
, 2023 (A) Mice were raised on a vitamin A deficient diet or a control diet and infected with HP followed by the MHV68.ORF73β-lactamase reporter virus, as in the timeline.
Mihir Pendse (17181225) +6 more
core +1 more source
Gammaherpesvirus-driven plasma cell differentiation regulates virus reactivation from latently infected B lymphocytes. [PDF]
PLoS Pathogens, 2009 Gammaherpesviruses chronically infect their host and are tightly associated with the development of lymphoproliferative diseases and lymphomas, as well as several other types of cancer.
Xiaozhen Liang +4 more
doaj +1 more source
Viral pseudoenzymes in infection and immunity
The FEBS Journal, Volume 287, Issue 19, Page 4300-4309, October 2020., 2020 Viral pseudoenzymes are represented by enzyme‐deficient homologs of glutamine amidotransferase (GAT), kinase, and superoxide dismutase that modulate the signaling output in immune defense, viral genome replication, and cell proliferation, respectively.
Ting‐Yu Wang +4 more
wiley +1 more source
PLoS ONE, 2014 Passage through the eukaryotic cell cycle is regulated by the activity of cyclins and their cyclin-dependent kinase partners. Rhadinoviruses, such as Kaposi's sarcoma-associated herpesvirus (KSHV) and murine gammaherpesvirus 68 (MHV68), encode a viral ...
Francine M Scott, Samuel H Speck
doaj +1 more source
RIP1 kinase activity is critical for skin inflammation but not for viral propagation
Journal of Leukocyte Biology, Volume 107, Issue 6, Page 941-952, June 2020., 2020 Inhibiting RIP1 has benefits to skin inflammation but not certain viral infections. Abstract Receptor interacting protein kinase 1 (RIP1) is a critical effector of inflammatory responses and cell death activation. Cell death pathways regulated by RIP1 include caspase‐dependent apoptosis and caspase‐independent necroptosis.
Joshua D. Webster +15 more
wiley +1 more source
Regulation of cGAS‐Mediated Immune Responses and Immunotherapy
Advanced Science, Volume 7, Issue 6, March 18, 2020., 2020 The cGAS‐STING pathway is central to innate immunity and must be tightly regulated. cGAS performs essential roles in numerous immune functions such as DNA sensing, antiviral defense, antitumor immunity, senescence, and DNA repair. Aberrant cGAS activation leads to autoimmune and inflammatory diseases.
Abdullah F. U. H. Saeed +4 more
wiley +1 more source
, 2023 (A) Timeline of intraperitoneal IL-4 complex (IL-4c), thioglycolate (Thio) treatments and MHV68.ORF73β-lactamase intraperitoneal infection (106 plaque forming units (PFU)). 5μg of IL-4 and 25 μg α-IL-4 were complexed and injected for LPM expansion.
Mihir Pendse (17181225) +6 more
core +1 more source
Oxidative Medicine and Cellular Longevity, Volume 2020, Issue 1, 2020., 2020 As an essential lipid, cholesterol is of great value in keeping cell homeostasis, being the precursor of bile acid and steroid hormones, and stabilizing membrane lipid rafts. As a kind of cholesterol metabolite produced by enzymatic or radical process, oxysterols have drawn much attention in the last decades.
Qin Cao +5 more
wiley +1 more source
Twist: a regulator of epithelial-mesenchymal transition in lung fibrosis. [PDF]
PLoS ONE, 2009 Several studies have implicated viral infection as an important factor in the pathogenesis of IPF and related fibrotic lung disorders. Viruses are thought to cause epithelial cell injury and promote epithelial-mesenchymal transition (EMT), a process ...
Veronika Pozharskaya +8 more
doaj +1 more source
Expansion of murine gammaherpesvirus latently infected B cells requires T follicular help.
PLoS Pathogens, 2014 X linked lymphoproliferative disease (XLP) is an inherited immunodeficiency resulting from mutations in the gene encoding the slam associated protein (SAP).
Christopher M Collins, Samuel H Speck
doaj +1 more source