Results 31 to 40 of about 1,598 (170)
Murine gamma-herpesvirus immortalization of fetal liver-derived B cells requires both the viral cyclin D homolog and latency-associated nuclear antigen. [PDF]
PLoS Pathogens, 2011 Human gammaherpesviruses are associated with the development of lymphoproliferative diseases and B cell lymphomas, particularly in immunosuppressed hosts.
Xiaozhen Liang +5 more
doaj +1 more source
Regulation of ribonucleoprotein condensates by RNase L during viral infection
WIREs RNA, Volume 14, Issue 4, July/August 2023., 2023 RNase L‐mediated mRNA decay inhibits stress granule assembly and promotes the assembly of RNase L‐dependent bodies. Abstract In response to viral infection, mammalian cells activate several innate immune pathways to antagonize viral gene expression. Upon recognition of viral double‐stranded RNA, protein kinase R (PKR) phosphorylates the alpha subunit ...
James M. Burke
wiley +1 more source
Interleukin 16 contributes to gammaherpesvirus pathogenesis by inhibiting viral reactivation.
PLoS Pathogens, 2020 Gammaherpesviruses have evolved various strategies to take advantage of host cellular factors or signaling pathways to establish a lifelong latent infection.
Shuai Liu +13 more
doaj +1 more source
Trakya University Journal of Natural Sciences, 2023 Gammaherpesviruses are associated with multiple types of tumor development and understanding the pathogenesis of these viruses has been the subject of various studies.
Scott Tibbetts, Mehmet Kara
doaj +1 more source
, 2023 (A-E) Tamoxifen treated Gata6flox/flox and Gata6Δ Mac mice were infected with the MHV68.ORF73β-lactamase reporter virus, as in Fig 3. PECs were collected at day 2 of MHV68 infection for flow analysis. (A) Representative flow plots of macrophage gating at
Mihir Pendse (17181225) +6 more
core +1 more source
Journal of Medical Virology, Volume 95, Issue 6, June 2023., 2023 Abstract Persistent high‐risk human papilloma virus (HR‐HPV) infection is the main risk factor for cervical cancer, threatening women's health. Despite growing prophylactic vaccination, annual cervical cancer cases are still increasing and show a trend of younger onset age. However, therapeutic approaches towards HPV infection are still limited.
Boning Li +8 more
wiley +1 more source
Comparison of MHV68/HP and HP/MHV68 coinfection models and mechanisms.
, 2023 (A) Model of HP challenge during MHV68 latency inducing reactivation through IL-4 and IL-13 signaling. (B) HP infection prior to MHV68 coinfection. HP-induced increased acute MHV68 infection is driven by LPM expansion.
Mihir Pendse (17181225) +6 more
core +1 more source
Journal of Immunology Research, Volume 2022, Issue 1, 2022., 2022 In recent years, there has been ample evidence illustrating the effect of microbiota on gut immunity, homeostasis, and disease. Most of these studies have engaged more efforts in understanding the role of the bacteriome in gut mucosal immunity and disease.
Njinju Asaba Clinton +6 more
wiley +1 more source
Modified Cross‐Linking, Ligation, and Sequencing of Hybrids (qCLASH) to Identify MicroRNA Targets
Current Protocols, Volume 1, Issue 10, October 2021., 2021 Abstract This protocol was designed to identify microRNA (miRNA) targetomes from smaller‐input samples by performing a simplified workflow of the Cross‐Linking and Sequencing of Hybrids (CLASH) technique developed in the Tollervey group. In this ribonomics‐based technique, Cross‐Linking and Immunoprecipitation (CLIP) of Argonaute (Ago) is combined with
Lauren A. Gay +2 more
wiley +1 more source
, 2023 Mice were raised on a vitamin A deficient diet or a control diet and infected with HP followed by the MHV68.ORF73β-lactamase reporter virus. PECs were collected on day 2 and day 4 of MHV68 infection.
Mihir Pendse (17181225) +6 more
core +1 more source