Results 51 to 60 of about 90,588 (222)
The contribution of natural killer complex loci to the development of experimental cerebral malaria.
PLoS ONE, 2014 BackgroundThe Natural Killer Complex (NKC) is a genetic region of highly linked genes encoding several receptors involved in the control of NK cell function.
Diana S Hansen +7 more
doaj +1 more source
Sex differences in variability across timescales in BALB/c mice. [PDF]
, 2017 BackgroundFemales are markedly underinvestigated in the biological and behavioral sciences due to the presumption that cyclic hormonal changes across the ovulatory cycle introduce excess variability to measures of interest in comparison to males. However,
Grant, Azure D +4 more
core +2 more sources
Mitochondrial haplotype and sex modulate responses to endurance exercise training
The Journal of Physiology, EarlyView.Abstract figure legend Using OKC‐HETB/W rats we demonstrate that mitochondrial haplotype influences training responses of endurance exercise. Overall OKC‐HETW rats showed greater responses than OKC‐HETB in exercise tolerance, mitochondrial bioenergetics, mitochondrial DNA (mtDNA) mutation frequencies and motor co‐ordination.
Bumsoo Ahn +8 more
wiley +1 more source
Laboratory Animal Research, 2018 Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed to obtain data on the characteristics of a ...
Hajin Nam +5 more
doaj +1 more source
Laboratory Animal Research, 2022 Background Inbred mice have several advantages, including genetic similarity to humans, a well-established gene manipulation system, and strong tolerance to inbreeding.
Hajin Nam +8 more
doaj +1 more source
International Journal of Cancer, Volume 158, Issue 5, Page 1336-1347, 1 March 2026.What's New? Small cell lung cancer (SCLC) is aggressive and difficult to treat but exhibits high levels of stathmin 1 (STMN1), a candidate therapeutic target. In this study, the authors synthesized a chlorambucil (Chb)‐conjugated pyrrole–imidazole polyamide (PIP) compound targeting the STMN1 promoter and DNA sequences and evaluated its efficacy in ...
Ryohei Yoshikawa +23 more
wiley +1 more source
Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation. [PDF]
PLoS ONE, 2012 Native (pre-existing) collaterals are arteriole-to-arteriole anastomoses that interconnect adjacent arterial trees and serve as endogenous bypass vessels that limit tissue injury in ischemic stroke, myocardial infarction, coronary and peripheral artery ...
Shiliang Wang +4 more
doaj +1 more source
Quality of Reporting and Adherence to ARRIVE Guidelines in Animal Studies for Chagas Disease Preclinical Drug Research: A Systematic Review [PDF]
, 2015 Publication of accurate and detailed descriptions of methods in research articles involving animals is essential for health scientists to accurately interpret published data, evaluate results and replicate findings. Inadequate reporting of key aspects of
García Bournissen, Facundo +2 more
core +4 more sources
Advanced Studies in Biology, 2015 Nitric oxide (NO) is one of dozens of lipophilic small molecules that is synthesized from amino acid L-Arginine, O2 and NADPH by nitric oxide synthase (NOS). There is increasing evidence that NO is an important molecular messenger involved in a wide variety of biological processes in different systems. One of the isoforms of NOS enzyme called inducible
Moslem Najafi +4 more
openaire +1 more source
Lysed Enterococcus faecalis FK-23 (LFK) Suppressing Allergic Responses in Mouse Models
Allergology International, 2005 Recently, several clinical trials have been published to discuss the possibility of probiotic supplementation, especially some products of lactic acid bacteria such as Lactobacillus and Bifidobacterium strains, in prevention and treatment of allergic ...
Takashi Shimada +6 more
doaj +1 more source