GENETIC ANALYSIS OF AUDIOGENIC SEIZURE SUSCEPTIBILITY IN C57BL/6J x DBA/2J RECOMBINANT INBRED STRAINS OF MICE [PDF]
Genetics, 1980 ABSTRACT The inheritance of susceptibility to audiogenic seizures (ASS) was studied in the C57BW6J (B6) and DBA/2j (D2) progenitor strains, their reciprocal F1 hybrids, backcross generations and in 21 B6 × D2 recombinant inbred (RI) strams of mice at 21 days of age.
Seyfried, T N, Yu, R K, Glaser, G H
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Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains [PDF]
, 2012 BACKGROUND: miRNAs are short single-stranded non-coding RNAs involved in post-transcriptional gene regulation that play a major role in normal biological functions and diseases. Little is currently known about how expression of miRNAs is regulated.
Chesler, E. +9 more
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Characterization of the T cell receptor repertoire causing collagen arthritis in mice [PDF]
, 1993 Collagen type II-induced arthritis (CIA) is generated in susceptible rodent strains by intradermal injections of homologous or heterologous native type II collagen in complete Freund's adjuvant.
Hood, Leroy E. +3 more
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A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior [PDF]
, 2015 Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Borevitz, Justin O. +13 more
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Virology Journal, 2012 Background The mouse represents an important model system to study the host response to influenza A infections and to evaluate new prevention or treatment strategies. We and others reported that the susceptibility to influenza A virus infections strongly
Dengler Leonie +4 more
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Foster dams rear fighters: strain-specific effects of within-strain fostering on aggressive behavior in male mice. [PDF]
PLoS ONE, 2013 It is well known that genes and environment interact to produce behavioral phenotypes. One environmental factor with long-term effects on gene transcription and behavior is maternal care.
Kimberly H Cox +2 more
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Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]
, 1975 Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Alkan +36 more
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Scientific Reports, 2023 Sensory stimuli are natural rewards in mice and humans. Consequently, preference for a drug reward relative to a sensory reward may be an endophenotype of addiction vulnerability.
Michael Leonardo +4 more
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Effects of environmental enrichment upon ethanol-induced conditioned place preference and pre-frontal BDNF levels in adolescent and adult mice [PDF]
, 2017 Environmental enrichment (EE) provides a non-pharmacological tool to alter drug-induced reward, yet its effects on ethanol-induced reward remain controversial. We analyzed adolescent vs.
Camarini, Rosana +6 more
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Hypothalamic Irak4 is a genetically controlled regulator of hypoglycemia-induced glucagon secretion
Molecular Metabolism, 2022 Objectives: Glucagon secretion to stimulate hepatic glucose production is the first line of defense against hypoglycemia. This response is triggered by so far incompletely characterized central hypoglycemia-sensing mechanisms, which control autonomous ...
Alexandre Picard +7 more
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