Results 21 to 30 of about 188 (98)

The adjuvant effect of polymuramil, a NOD1 and NOD2 agonist, differs when immunizing mice of different inbred lines with nonstructural hepatitis C virus (Flaviviridae: Hepacivirus)proteins and is synergistically enhanced in combination with pyrogenalum, a TLR4 agonist

Вопросы вирусологии, 2023
Introduction. Hepatitis C is a liver disease with high chronicity, the cause of cirrhosis and hepatocarcinoma. The main obstacle to controlling hepatitis C is the lack of vaccines.
Ekaterina I. Lesnova, Olga V. Masalova, Kristina Yu. Permyakova, Natalia A. Demidova, Vladimir T. Valuev-Elliston, Alexandr V. Ivanov, Alla A. Kushch   +6 more
doaj   +1 more source

Confirmation of multiple seizure susceptibility QTLs on chromosome 15 in C57BL/6J and DBA/2J inbred mice

Physiological Genomics, 2010
To confirm seizure susceptibility (SZS) quantitative trait loci (QTLs) on chromosome (chr) 15 identified previously using C57BL/6J (B6) and DBA/2J (D2) mice and to refine their genomic map position, we studied a set of three congenic strains in which overlapping segments of chr 15 from D2 were transferred onto the B6 background.
Wade H. Berrettini, George G. Smith, George G. Smith, Glenn A. Doyle, Falk W. Lohoff, Candice L. Schwebel, Thomas N. Ferraro, Suzett E. Ruiz, John U. Oleynick, Russell J. Buono   +9 more
openaire   +4 more sources

Enhancement of Leishmania amazonensis infection in BCG non-responder mice by BCG-antigen specific vaccine

Memorias do Instituto Oswaldo Cruz, 1992
Different patterns of cutaneous leishmaniasis can be induced when a challenge of alike dose of Leishmania amazonensis amastigotes in various inbred strains was applied.
Kátia da Silva Calabrese, Sylvio Celso Gonçalves da Costa   +1 more
doaj   +1 more source

Metabolic Adaptations of Three Inbred Strains of Mice (C57BL/6, DBA/2, and 129T2) in Response to a High-Fat Diet [PDF]

The Journal of Nutrition, 2004
Although it is now becoming more evident that the strain of mouse used to generate genetically modified models for the study of endocrine disorders contributes to the ensuing phenotype, metabolic characterization of these common strains used to produce genetically altered mice has been limited.
Valentina Jovanovska, Christine M. Massa, Sofianos Andrikopoulos, Alexandra Funkat, Joseph Proietto   +4 more
openaire   +3 more sources

Differences in the Flexibility of Switching Learning Strategies and CREB Phosphorylation Levels in Prefrontal Cortex, Dorsal Striatum, and Hippocampus in Two Inbred Strains of Mice

Frontiers in Behavioral Neuroscience, 2016
Flexibility in using different learning strategies was assessed in two different inbred strains of mice, the C57BL/6 and DBA/2 strains. Mice were trained sequentially in two different Morris water maze protocols that tested their ability to switch their ...
Woo-Hyun Cho, Jung-Soo Han
doaj   +1 more source

Comparison of Adult Hippocampal Neurogenesis and Susceptibility to Treadmill Exercise in Nine Mouse Strains

Neural Plasticity, 2017
The genetic background of mice has various influences on the efficacy of physical exercise, as well as adult neurogenesis in the hippocampus. In this study, we investigated the basal level of hippocampal neurogenesis, as well as the effects of treadmill ...
Jong Whi Kim, Sung Min Nam, Dae Young Yoo, Hyo Young Jung, Il Yong Kim, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoon   +7 more
doaj   +1 more source

THE EFFECTS OF GROUP VERSUS SINGLE HOUSING ON HOME CAGE BEHAVIOUR IN TWO STRAINS OF LABORATORY MICE

Slovenian Veterinary Research, 2019
Studying the behavioural patterns of animals in their house may help to understand their needs, but there has been a little investigation of home-cage behaviours in commonly used inbred strains of mice such as C57BL/6 and DBA/2. Therefore, understanding
Ahmed F. Abou-Elnaga, Ibrahim F. Rehan, Ralph R Thompson, Usama A Abou-Ismail, Motamed E Mahmoud, Radi A Mohamed, Hesham H Mohammed, Ahmed A Sabek, Mohamed Z Elhussiny   +8 more
doaj   +1 more source

Insufficient generation of mycobactericidal mediators and inadequate level of phagosomal maturation are related with susceptibility to virulent Mycobacterium tuberculosis infection in mouse macrophages

Frontiers in Microbiology, 2016
Tuberculosis is caused by Mycobacterium tuberculosis (M. tuberculosis, Mtb) infection, and it remains major life-threatening infectious diseases worldwide. Although Mtb has infected one-third of the present human population, only 5-10% of immunocompetent
Hyo-Ji eLee, Hyun-Jeong eKo, Yu-Jin eJung   +2 more
doaj   +1 more source

Immobilization induced osteopenia is strain specific in mice

Bone Reports, 2015
Immobilization causes rapid and massive bone loss. By comparing Botulinum Toxin A (BTX)-induced bone loss in mouse strains with different genetic backgrounds we investigated whether the genetic background had an influence on the severity of the ...
Andreas Lodberg, Jens Bay Vegger, Michael Vinkel Jensen, Christian Mirian Larsen, Jesper Skovhus Thomsen, Annemarie Brüel   +5 more
doaj   +1 more source

Quantitative Trait Loci Analysis of Structural and Material Skeletal Phenotypes in C57BL/6J and DBA/2 Second-Generation and Recombinant Inbred Mice [PDF]

Journal of Bone and Mineral Research, 2005
Abstract QTL analyses identified several chromosomal regions influencing skeletal phenotypes of the femur and tibia in BXD F2 and BXD RI populations of mice. QTLs for skeletal traits co-located with each other and with correlated traits such as body weight and length, adipose mass, and serum alkaline phosphatase ...
Lang, Dean H., Sharkey, Neil A., Mack, Holly A. (R18996), Vogler, George P., Vandenbergh, David J., Blizard, David A., Stout, Joseph T., McClearn, Gerald E.   +7 more
openaire   +4 more sources