Results 1 to 10 of about 132,810 (216)
A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. [PDF]
PLoS ONE, 2009 Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Richard Williams +13 more
doaj +5 more sources
In silico candidate variant and gene identification using inbred mouse strains [PDF]
PeerJ, 2021 Mice are the most widely used animal model to study genotype to phenotype relationships. Inbred mice are genetically identical, which eliminates genetic heterogeneity and makes them particularly useful for genetic studies.
Matthias Munz +4 more
doaj +2 more sources
Scientific Reports, 2023 Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater and more complex than that in a single inbred strain of mice ...
Kishore R. Alugupalli +11 more
doaj +1 more source
Sperm morphology in two house mouse subspecies: do wild-derived strains and wild mice tell the same story? [PDF]
PLoS ONE, 2014 Being subject to intense post-copulatory selection, sperm size is a principal determining component of male fitness. Although previous studies have presented comparative sperm size data at higher taxonomic levels, information on the evolution of sperm ...
Jana Albrechtová +4 more
doaj +1 more source
Медицинская иммунология, 2014 . The course of infections caused by intracellular parasitic bacteria Salmonella typhimurium and Chlamidophila pneumoniae was compared for inbred strains of mice with genetically determined susceptibity (I/St) or resistance (A/Sn) to Mycobacterium ...
D. V. Balunets +5 more
doaj +3 more sources
Rift Valley Fever Virus Is Lethal in Different Inbred Mouse Strains Independent of Sex
Frontiers in Microbiology, 2020 Rift Valley fever virus (RVFV) is a zoonotic arbovirus affecting humans and livestock in Africa and the Arabian Peninsula. The majority of human cases are mild and self-limiting; however, severe cases can result in hepatitis, encephalitis, or hemorrhagic
Haley N. Cartwright +5 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Mycoplasma pneumoniae (Mp) is a highly contagious respiratory pathogen responsible for human community-acquired pneumonia. The number of antibiotic-resistant Mp strains is increasing; therefore, to develop novel therapeutics, it is crucial to precisely ...
Shigeyuki Tamiya +11 more
doaj +1 more source
Analysis of structural variation among inbred mouse strains
BMC Genomics, 2023 Background ‘Long read’ sequencing methods have been used to identify previously uncharacterized structural variants that cause human genetic diseases.
Ahmed Arslan +10 more
doaj +1 more source
Inbred mouse strains and genetic stability: a review
Animal, 2011 Inbred mice were essential animal models for scientific research during the 20th century and will contribute decisive results in the current and next centuries.
J. Casellas
doaj +1 more source
Ethanol Teratogenesis in Five Inbred Strains of Mice [PDF]
Alcoholism: Clinical and Experimental Research, 2009 Background: Previous studies have demonstrated individual differences in susceptibility to the detrimental effects of prenatal ethanol exposure. Many factors, including genetic differences, have been shown to play a role in susceptibility and resistance, but few studies have investigated the range of genetic variation in rodent models.Methods: We ...
Chris, Downing +4 more
openaire +2 more sources