Results 51 to 60 of about 145,801 (250)

Strain variation in spermatozoal glycosidases in inbred mice

open access: yesGenetical Research, 1978
SUMMARYTen glycosidases were measured in suspensions of spermatozoa from the vasa deferentia of two inbred mouse strains and their intercrosses. Eight of these glycosidases were associated with the sperm cells and all of these showed genetical variation between the strains except α-l-fucosidase with optimal activity at pH 5·4.
Self, S J, Winchester, B G, Archer, J R
openaire   +3 more sources

Ventilatory Phenotypes among Four Strains of Adult Rats. [PDF]

open access: yes, 2002
Our purpose in this study was to identify different ventilatory phenotypes among four different strains of rats. We examined 114 rats from three in-house, inbred strains and one outbred strain: Brown Norway (BN;n = 26), Dahl salt-sensitive (n = 24), Fawn-
Dwinell, Melinda R.   +4 more
core   +2 more sources

Mechanistic insights into the primary and secondary alterations of renal ion and water transport in the distal nephron

open access: yesJournal of Internal Medicine, Volume 293, Issue 1, Page 4-22, January 2023., 2023
Abstract The kidneys, by equilibrating the outputs to the inputs, are essential for maintaining the constant volume, pH, and electrolyte composition of the internal milieu. Inability to do so, either because of internal kidney dysfunction (primary alteration) or because of some external factors (secondary alteration), leads to pathologies of varying ...
Nahid Tabibzadeh, Gilles Crambert
wiley   +1 more source

Inbreeding effects on telomeres in hatchling sand lizards (Lacerta agilis): An optimal family affair?

open access: yesMolecular Ecology, Volume 31, Issue 24, Page 6605-6616, December 2022., 2022
Abstract Telomeres are nucleotide‐protein caps, predominantly at the ends of Metazoan linear chromosomes, showing complex dynamics with regard to their lengthening and shortening through life. Their complexity has entertained the idea that net telomere length and attrition could be valuable biomarkers of phenotypic and genetic quality of their bearer ...
Mats Olsson   +6 more
wiley   +1 more source

Tympanometry assessment of 61 inbred strains of mice [PDF]

open access: yesHearing Research, 2007
Otitis media (OM) accounts for more than 20 million clinic visits in the United States every year. Resistance to antibiotics has hampered current management of the disease. Identification of genetic factors underlying susceptibility to OM is greatly needed in order to develop alternative treatment strategies.
Zheng, Q Y   +3 more
openaire   +4 more sources

Genetic regulation of mouse liver metabolite levels. [PDF]

open access: yes, 2014
We profiled and analyzed 283 metabolites representing eight major classes of molecules including Lipids, Carbohydrates, Amino Acids, Peptides, Xenobiotics, Vitamins and Cofactors, Energy Metabolism, and Nucleotides in mouse liver of 104 inbred and ...
Bennett, Brian J   +11 more
core   +1 more source

Glucose Absorption in Highly Inbred Strains of Mice.

open access: yesExperimental Biology and Medicine, 1952
Conclusions1. Glucose absorption in the mouse has been studied. Increasing the concentration of administered solution results in an increase in the amount of glucose absorbed. 2. Glucose solutions of 75% concentration were absorbed somewhat more readily by mice of the C57 strain than by those of the A strain (p = 0.015). 3.
George R. Cowgill   +2 more
openaire   +3 more sources

Susceptibility differences of inbred strains of mice to blastomycosis [PDF]

open access: yesInfection and Immunity, 1981
The susceptibility of inbred strains of mice to pulmonary blastomycosis was studied to derive information relevant to host resistance and genetic background. Initial studies with eight strains with various H-2 backgrounds revealed the C3H/HeJ strain to be highly susceptible and DBA/1J mice to be resistant. These observations were confirmed with various
Morozumi, P A   +2 more
openaire   +3 more sources

Experimentation with Animals: A Key Aspect of the 3Rs. The Genetic Quality [PDF]

open access: yes, 2019
The genetic quality of laboratory animals is essential for reproducibility of scientific research. Working with animals of certifiedgenetic quality is still a pending issue in Argentina due to the lack of routine genetic controls, of information on the ...
Castillo, Nadia Sabiela   +4 more
core   +1 more source

The bone marrow micronucleus test and metronidazole genotoxicity in different strains of mice (Mus musculus)

open access: yesGenetics and Molecular Biology, 2007
The mouse (Mus musculus) bone marrow micronucleus test was carried out using 24 outbred National Institutes of Health (NIH) mice, 24 inbred Swiss Webster (CFW) mice and 20 inbred Bagg albino/color locus Jackson (BALB/cJ) mice.
Ximena C. Abrevaya   +2 more
doaj   +1 more source

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