Results 51 to 60 of about 1,877,211 (239)

The bone marrow micronucleus test and metronidazole genotoxicity in different strains of mice (Mus musculus)

open access: yesGenetics and Molecular Biology, 2007
The mouse (Mus musculus) bone marrow micronucleus test was carried out using 24 outbred National Institutes of Health (NIH) mice, 24 inbred Swiss Webster (CFW) mice and 20 inbred Bagg albino/color locus Jackson (BALB/cJ) mice.
Ximena C. Abrevaya   +2 more
doaj   +1 more source

Strain variation in spermatozoal glycosidases in inbred mice

open access: yesGenetical Research, 1978
SUMMARYTen glycosidases were measured in suspensions of spermatozoa from the vasa deferentia of two inbred mouse strains and their intercrosses. Eight of these glycosidases were associated with the sperm cells and all of these showed genetical variation between the strains except α-l-fucosidase with optimal activity at pH 5·4.
Self, S J, Winchester, B G, Archer, J R
openaire   +2 more sources

Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco   +2 more
wiley   +1 more source

Genealogies of mouse inbred strains

open access: yes, 2000
The mouse is a prime organism of choice for modelling human disease. Over 450 inbred strains of mice have been described, providing a wealth of different genotypes and phenotypes for genetic and other studies.
E M Fisher (16062389)   +6 more
core   +3 more sources

Influence of Trypanosoma cruzi strain on the pathogenesis of chronic myocardiopathy in mice

open access: yesMemorias do Instituto Oswaldo Cruz, 1990
The murine model of chronic Chaga's myocardiopathy was developed in 201 inbred and outbred mice. The experimental groups consisted of 1st: 73 inbred AKR and A/J mice inoculated with one of the following.
Sonia G. Andrade
doaj   +1 more source

Baseline podocyte‐associated state and persistent cell–matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Two closely related BALB/c substrains exhibit different early responses to adriamycin (ADR)‐induced nephropathy. BALB/cByJcl mice showed lower baseline WT1‐positive nuclei counts and NPHS1 immunoreactivity than BALB/cAJcl mice, together with extracellular matrix and integrin programs that were enriched at baseline and persisted at Day 5.
Ryuya Nakagawa   +5 more
wiley   +1 more source

SPERMATOGENESIS INDICES IN INBRED STRAINS DD/HE AND BALB/CLAC AND THEIR F1 RECIPROCAL CROSSES

open access: yesВавиловский журнал генетики и селекции, 2014
We have shown that among 13 inbred mice strains males the DD/He strain has the lowest proportion of mobile sperm and moderate sperm count and proportion of abnormal sperm heads.
M. A. Kleshchev   +2 more
doaj  

The collaborative cross strains and their founders vary widely in cocaine-induced behavioral sensitization

open access: yesFrontiers in Behavioral Neuroscience, 2022
Cocaine use and overdose deaths attributed to cocaine have increased significantly in the United States in the last 10 years. Despite the prevalence of cocaine use disorder (CUD) and the personal and societal problems it presents, there are currently no ...
Sarah A. Schoenrock   +23 more
doaj   +1 more source

Born this way: Does variation in perinatal limb bone morphology predict adult locomotor repertoire in primates?

open access: yesThe Anatomical Record, EarlyView.
Abstract Primates show a high degree of locomotor diversity that engenders similar variance in limb bone cross‐sectional geometry and bending strength: leaping primates have stronger hindlimb bones whereas suspensory species have stronger forelimb bones.
Angela M. Mossor   +7 more
wiley   +1 more source

Placentophagia in Nonpregnant Nulliparous Mice: A Genetic Investigation [PDF]

open access: yes, 1975
The genetic influence on the response of nonpregnant nulliparous mice to foster placenta was investigated. Two highly inbred strains (BALB/cBy and C57BL/6By), their F1 hybrids, a backcross generation, and seven recombinant-inbred strains derived from the
Kristal, M B   +3 more
core  

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