Results 61 to 70 of about 259,574 (259)

Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. [PDF]

open access: yes, 2017
Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity.
Cho, Kiho   +3 more
core   +2 more sources

Genetic dependence of central corneal thickness among inbred strains of mice.

open access: yesInvestigative Ophthalmology and Visual Science, 2010
PURPOSE Central corneal thickness (CCT) exhibits broad variability. For unknown reasons, CCT also associates with diseases not typically considered corneal, particularly glaucoma.
Geoffrey D. Lively   +7 more
semanticscholar   +1 more source

Glucose Absorption in Highly Inbred Strains of Mice.

open access: yesExperimental Biology and Medicine, 1952
Conclusions1. Glucose absorption in the mouse has been studied. Increasing the concentration of administered solution results in an increase in the amount of glucose absorbed. 2. Glucose solutions of 75% concentration were absorbed somewhat more readily by mice of the C57 strain than by those of the A strain (p = 0.015). 3.
George R. Cowgill   +2 more
openaire   +3 more sources

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis   +5 more
wiley   +1 more source

The bone marrow micronucleus test and metronidazole genotoxicity in different strains of mice (Mus musculus)

open access: yesGenetics and Molecular Biology, 2007
The mouse (Mus musculus) bone marrow micronucleus test was carried out using 24 outbred National Institutes of Health (NIH) mice, 24 inbred Swiss Webster (CFW) mice and 20 inbred Bagg albino/color locus Jackson (BALB/cJ) mice.
Ximena C. Abrevaya   +2 more
doaj   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Influence of Trypanosoma cruzi strain on the pathogenesis of chronic myocardiopathy in mice

open access: yesMemorias do Instituto Oswaldo Cruz, 1990
The murine model of chronic Chaga's myocardiopathy was developed in 201 inbred and outbred mice. The experimental groups consisted of 1st: 73 inbred AKR and A/J mice inoculated with one of the following.
Sonia G. Andrade
doaj   +1 more source

Experimentation with Animals: A Key Aspect of the 3Rs. The Genetic Quality [PDF]

open access: yes, 2019
The genetic quality of laboratory animals is essential for reproducibility of scientific research. Working with animals of certifiedgenetic quality is still a pending issue in Argentina due to the lack of routine genetic controls, of information on the ...
Castillo, Nadia Sabiela   +4 more
core   +1 more source

FURTHER STUDIES OF THE STIMULATION OF DNA SYNTHESIS IN CULTURES OF SPLEEN CELL SUSPENSIONS BY HOMOLOGOUS CELLS IN INBRED STRAINS OF MICE AND RATS

open access: yesJournal of Experimental Medicine, 1965
The early proliferative response previously demonstrated in rabbits has now been shown to follow the mixing of spleen cell suspensions from 2 inbred strains of mice or rats.
R. Dutton
semanticscholar   +1 more source

Gentle Label‐Free Nonlinear Optical Imaging Relaxes Linear‐Absorption‐Mediated Triplet

open access: yesAdvanced Science, EarlyView.
The phototoxicity in nonlinear optical microscopy arises mainly from linear absorption of intrinsic biomolecules rather than nonlinear absorption. This mechanism is supported by a reproducible phototoxicity assay based on widely available chicken breast.
Geng Wang   +4 more
wiley   +1 more source

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