Results 61 to 70 of about 276,503 (245)
Advanced MRI for cardiac assessment in mice [PDF]
Heart failure is a leading cause of mortality in the Western world. The mouse is a widely used model for a number of diseases, induced by genetic modification or surgical intervention. When performing experiments in mice, in vivo magnetic resonance imaging (MRI) can be used to evaluate heart anatomy and function at multiple levels.
arxiv
Lifespan modulation in mice and the confounding effects of genetic background [PDF]
We are currently in the midst of a revolution in ageing research, with several dietary, genetic and pharmacological interventions now known to modulate ageing in model organisms.
Mulvey, Lorna+2 more
core +1 more source
Hydronephrosis in inbred strains of mice with particular reference to the BRVR strain [PDF]
Hydronephrosis occurred in 6 of the 13 inbred mouse strains maintained in the same colony. Its incidence was high only in the BRVR strain, where about half of the cases could only be detected microscopically. There was no concomitant infection even in severely abnormal BRVR kidneys and the incidence of the condition was not influenced by dietary ...
Taylor, D M, Fraser, H
openaire +3 more sources
Cocaine use and overdose deaths attributed to cocaine have increased significantly in the United States in the last 10 years. Despite the prevalence of cocaine use disorder (CUD) and the personal and societal problems it presents, there are currently no ...
Sarah A. Schoenrock+23 more
doaj +1 more source
Hyaline Arteriolosclerosis in 30 Strains of Aged Inbred Mice [PDF]
During a screen for vascular phenotypes in aged laboratory mice, a unique discrete phenotype of hyaline arteriolosclerosis of the intertubular arteries and arterioles of the testes was identified in several inbred strains. Lesions were limited to the testes and did not occur as part of any renal, systemic, or pulmonary arteriopathy or vasculitis ...
Cooper, Timothy K+7 more
openaire +4 more sources
SPERMATOGENESIS INDICES IN INBRED STRAINS DD/HE AND BALB/CLAC AND THEIR F1 RECIPROCAL CROSSES
We have shown that among 13 inbred mice strains males the DD/He strain has the lowest proportion of mobile sperm and moderate sperm count and proportion of abnormal sperm heads.
M. A. Kleshchev+2 more
doaj
Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice. [PDF]
Background: P. aeruginosa is one of the top three causes of opportunistic human bacterial infections. The remarkable variability in the clinical outcomes of this infection is thought to be associated with genetic predisposition.
A Bragonzi+62 more
core +1 more source
Inbred mouse strains and genetic stability: a review
Inbred mice were essential animal models for scientific research during the 20th century and will contribute decisive results in the current and next centuries.
J. Casellas
doaj
Background/Aims: Our laboratory discovered a Kunming mouse with enormous electroretinogram (ERG) defects. Its auditory brainstem response (ABR) threshold was significantly elevated and closely resembled the features of Usher syndrome (USH).
Weiming Yan+11 more
doaj +1 more source
Strain-dependent variations in stress coping behavior are mediated by a 5-HT/GABA interaction within the prefrontal corticolimbic system [PDF]
Background: Serotonin and γ- Aminobutyric acid (GABA) transmission is crucial in coping strategies. Methods: Here, using mice from 2 inbred strains widely exploited in behavioral neurochemistry, we investigated whether serotonin transmission in medial ...
ANDOLINA, DIEGO+3 more
core +1 more source