Results 81 to 90 of about 135,853 (215)
Frontiers in Endocrinology, 2019 Responses to a high fat, high sucrose (HFHS) diet vary greatly among inbred strains of mice. We sought to examine the epigenetic (DNA methylation) changes underlying these differences as well as variation in weight loss when switched to a low-fat chow ...
Chantle R. Edillor +5 more
doaj +1 more source
Auditory brainstem responses in 10 inbred strains of mice [PDF]
Brain Research, 2006 The auditory brainstem response (ABR) is an evoked potential response of auditory activity in the auditory nerve and subsequent fiber tracts and nuclei within the auditory brainstem pathways. The threshold, amplitude, and latency analysis of the ABR provides information on the peripheral hearing status and the integrity of brainstem pathways.
Zhou, X +4 more
openaire +3 more sources
Reduced Dietary Protein Induces Changes in the Dental Proteome
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs +2 more
wiley +1 more source
Behavioral Profiles of Genetically Selected Aggressive and Nonaggressive Male Wild House Mice in Two Anxiety Tests [PDF]
, 2000 Artificially selected aggressive (SAL) and non-aggressive (LAL) male house mice were tested in a hexagonal tunnel maze and light–dark preference (LD) box to determine if the bidirectional selection for aggressive behavior leads to a coselection for ...
Hof, Maleen, +6 more
core +2 more sources
Spontaneous Testicular Teratomas in an Inbred Strain of Mice [PDF]
Proceedings of the National Academy of Sciences, 1954 Descriptions of teratoid tumors of the mammalian testis, other than for man and ie horse, are ,are. In mice'oteratoma testis has not heretofore been reported. urthermore,.there are only a few descriptions of the ovarian counterpart of this 'pe of tumor in the mouse.", 2, 3, 4 In view of the paucity of information concerng teratomas in mice, their ...
Stevens, L C, Little, C C
openaire +2 more sources
Journal of Intelligent Medicine, EarlyView.Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source
Experimental rat models of chronic allograft nephropathy: a review [PDF]
, 2014 Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core +2 more sources
Evidence of emerging transcriptome mediators of Alzheimer's disease in canine cognitive dysfunction
Brain Pathology, EarlyView.Canine cognitive dysfunction (CCD) may be a promising model of Alzheimer's disease (AD). To assess AD‐related molecular signatures in CCD, we generated transcriptome data on dog cortex and plasma extracellular vesicles (EVs). CCD‐related transcriptome changes were similar to those in aging/AD humans and were detectable in EVs from the same animals ...
Shelby C. Osburn +7 more
wiley +1 more source
Anatomic correlates of strial presbycusis in recombinant inbred mouse strains [PDF]
, 2010 This project attempts to identify anatomic features that predict the range of the ‘normal’ endocochlear potential in young inbred mice. Cochlear lateral wall histologic metrics were compared in recombinant inbred (RI) mouse strains formed from BALB/c and
Walkonis, Christina M
core +1 more source
Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice [PDF]
, 2013 Background: Murine models are a crucial component of gut microbiome research. Unfortunately, a multitude of genetic backgrounds and experimental setups, together with inter-individual variation, complicates cross-study comparisons and a global ...
Brinkman, Brigitta +7 more
core +3 more sources