Results 181 to 190 of about 2,431,068 (346)

Normal spermatogenesis and fertility in <i>Spmip8</i> deficiency male mice. [PDF]

Biochem Biophys Rep
Zhang Z, Hu M, Yan D, Zhao Y, Tao W, Chen S, Qi M, Luo L, Jiang X, Xu B, Bai S.   +10 more
europepmc   +1 more source

From Knockout Mice to Knockout Rats [PDF]

Neurosurgery, 2003
openaire   +1 more source

Increased adipose tissue in male and female estrogen receptor-α knockout mice

, 2000
P. Heine, Julia A. Taylor, G. Iwamoto, D. Lubahn, P. Cooke   +4 more
semanticscholar   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

METTL4 regulates synaptic UCP2 N6-adenosine methylation to mediate pain hypersensitivity in female mice. [PDF]

Cell Mol Life Sci
Wu Y, Luo Y, Xiao Q, Xu X, Jin W, Li L, Liu C, He Z, Li Z, Li J, Yang X, Jiang F, Yang Z, Ma D, Ke C, Xiang H.   +15 more
europepmc   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

DDRGK1 preserves intervertebral disc development through ufmylation. [PDF]

Cell Mol Life Sci
Lu M, Zhou T, Yang X, Liu K, Rong K, Ma P, Qin A, Zhao J.   +7 more
europepmc   +1 more source

Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice.

Proceedings of the National Academy of Sciences of the United States of America, 1999
A. Zimmer, A. Zimmer, A. Hohmann, M. Herkenham, T. Bonner   +4 more
semanticscholar   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

GLP-1 physiology and pharmacology along the gut-brain axis. [PDF]

J Clin Invest
Beutler LR.
europepmc   +1 more source