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Osteocytic Pink1/Prkn modulates M6P metabolism and contributes to GC-induced bone loss. [PDF]
Mei J +9 more
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Abnormal Stress Reduced miR-330 Supplementation Alleviates Osteoarthritis Progression by Suppressing Osteochondral Catabolism. [PDF]
Zou L +8 more
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Modification of early behavioural, physiological and neuropathological endpoints by syntaxin-6 knockout in a humanised P301S transgenic model of tauopathy. [PDF]
Hill E +15 more
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TFF1-mediated suppression of the TCA cycle promotes bone metastasis in triple-negative breast cancer. [PDF]
Chen H +8 more
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The role of the cGAS/STING pathway in skeletal muscle regeneration: modulation of inflammation, macrophage polarization, and oxidative stress. [PDF]
Liu X +10 more
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Seminars in Cancer Biology, 1996
The xeroderma pigmentosum group A correcting (XPA) gene encodes a DNA binding zinc-finger protein that recognizes DNA damage. As such the XPA protein participates in the initial step of the process of nucleotide excision repair. The multicomponent nucleotide excision repair pathway is one of the most thoroughly studied mechanisms that defends both ...
de Vries, A, van Steeg, H
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The xeroderma pigmentosum group A correcting (XPA) gene encodes a DNA binding zinc-finger protein that recognizes DNA damage. As such the XPA protein participates in the initial step of the process of nucleotide excision repair. The multicomponent nucleotide excision repair pathway is one of the most thoroughly studied mechanisms that defends both ...
de Vries, A, van Steeg, H
openaire +3 more sources
Knockout Mice in Xenobiotic Metabolism
Drug Metabolism Reviews, 2003Mice in which genes for drug metabolizing enzymes have been deleted or inactivated have great potential to further our understanding of the functions of these enzymes and their role in toxicology a...
Henderson, Colin J. +4 more
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Xenobiotic receptor knockout mice
Toxicology Letters, 1995Administration of certain foreign chemicals to animals elicits responses that are due to receptor-mediated activation of gene expression. Among the most well studied receptors are the Ah receptor (AHR) that binds 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds and the peroxisome proliferator-activated receptors, PPARs, that mediate gene ...
F J, Gonzalez +4 more
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