Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglyceryl transferase gene lgt on ABC transporter function and on growth in vivo [PDF]
, 2012 Lipoproteins are an important class of surface associated proteins that have diverse roles and frequently are involved in the virulence of bacterial pathogens.
A Bidossi +91 more
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Frontiers in Cellular and Infection Microbiology, 2022 Yersinia pestis is the etiological agent of plague, a deadly infectious disease that has caused millions of deaths throughout history. Obtaining iron from the host is very important for bacterial pathogenicity. Y.
Yulu Chen +20 more
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Systemic autoimmunity in BAFF‐R‐mutant A/WySnJ strain mice [PDF]
European Journal of Immunology, 2008 AbstractSystemic lupus erythematosis is an autoimmune disease of unknown etiology. Lupus pathology is thought to reflect autoantibody‐mediated damage due to a failure of B lymphocyte tolerance. Since excessive B cell‐activating factor belonging to the TNF family (BAFF) expression correlates with human and murine lupus, and BAFF signals B cell survival ...
Christopher G, Mayne +3 more
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Histocompatible Colour Mutant from CBA/Lab Strain of Mice [PDF]
Nature, 1961 THE progeny from a breeding pair of CBA /Lab mice, a strain which is propagated by brother × sister mating, were found to have grey agouti coats in contrast to the usual wild-type agouti of the strain.
Brown, A M, Cook, M J
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Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. [PDF]
PLoS Genetics, 2016 TGFβs act through canonical and non-canonical pathways, and canonical signals are transduced via Smad2 and Smad3. However, the contribution of canonical vs.
Weiguang Wang +5 more
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PLoS Pathogens, 2021 The Peptidoglycan (PG) cell wall of the Lyme disease (LD) spirochete, Borrelia burgdorferi (Bb), contributes to structural and morphological integrity of Bb; is a persistent antigen in LD patients; and has a unique pentapeptide with L-Ornithine as the ...
Yue Chen +7 more
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Rim Pathway-Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation [PDF]
, 2017 ACKNOWLEDGMENTS We acknowledge Jennifer Lodge, Woei Lam, and Rajendra Upadhya for developing and sharing the chitin and chitosan MTBH assay. We thank Todd Brennan of Duke University for providing MyD88-deficient mice.
Carol Munro +8 more
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An novel strategy for brucella differential vaccine combined with colloidal gold immunochromatographic strips based on mutants of brucella melitensis m5-90 [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 There is a requirement to develop an novel vaccine to distinguish between vaccinated and infected animals after vaccination. Two mutants of Brucella melitensis M5-90Δbp261 and M5-90Δbp262, knockout of the fragments amino acids 55-152 and 22-185 ...
ZHANG H +9 more
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The effect of human factor H on immunogenicity of meningococcal native outer membrane vesicle vaccines with over-expressed factor H binding protein. [PDF]
PLoS Pathogens, 2012 The binding of human complement inhibitors to vaccine antigens in vivo could diminish their immunogenicity. A meningococcal ligand for the complement down-regulator, factor H (fH), is fH-binding protein (fHbp), which is specific for human fH.
Peter T Beernink +5 more
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Journal of Fungi, 2020 The Candida parapsilosis genome encodes for five agglutinin-like sequence (Als) cell-wall glycoproteins involved in adhesion to biotic and abiotic surfaces. The work presented here is aimed at analyzing the role of the two still uncharacterized ALS genes
Marina Zoppo +9 more
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