Results 11 to 20 of about 252,850 (254)

Insulin 3-like hormone and its role in epididymo-testicular descent

International Brazilian Journal of Urology, 2007
PURPOSE: The role of insulin 3-like (Insl3) hormone signaling in the testicular descent process has been demonstrated. The purpose of the present study was to evaluate epididymal development in Insl3-deficient mice.
Faruk Hadziselimovic, Ibrahim Adham
doaj   +1 more source

Role of CpALS4790 and CpALS0660 in Candida parapsilosis Virulence: Evidence from a Murine Model of Vaginal Candidiasis

Journal of Fungi, 2020
The Candida parapsilosis genome encodes for five agglutinin-like sequence (Als) cell-wall glycoproteins involved in adhesion to biotic and abiotic surfaces. The work presented here is aimed at analyzing the role of the two still uncharacterized ALS genes
Marina Zoppo, Fabrizio Fiorentini, Cosmeri Rizzato, Mariagrazia Di Luca, Antonella Lupetti, Daria Bottai, Marisa Colone, Annarita Stringaro, Flavia De Bernardis, Arianna Tavanti   +9 more
doaj   +1 more source

Helicobacter pylori colonization ameliorates glucose homeostasis in mice through a PPAR γ-dependent mechanism. [PDF]

PLoS ONE, 2012
There is an inverse secular trend between the incidence of obesity and gastric colonization with Helicobacter pylori, a bacterium that can affect the secretion of gastric hormones that relate to energy homeostasis. H.
Josep Bassaganya-Riera, Maria Gloria Dominguez-Bello, Barbara Kronsteiner, Adria Carbo, Pinyi Lu, Monica Viladomiu, Mireia Pedragosa, Xiaoying Zhang, Bruno W Sobral, Shrinivasrao P Mane, Saroj K Mohapatra, William T Horne, Amir J Guri, Michael Groeschl, Gabriela Lopez-Velasco, Raquel Hontecillas   +15 more
doaj   +1 more source

Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain

eLife, 2021
Activating LRRK2 mutations cause Parkinson’s disease, and pathogenic LRRK2 kinase interferes with ciliogenesis. Previously, we showed that cholinergic interneurons of the dorsal striatum lose their cilia in R1441C LRRK2 mutant mice (Dhekne et al., 2018).
Shahzad S Khan, Yuriko Sobu, Herschel S Dhekne, Francesca Tonelli, Kerryn Berndsen, Dario R Alessi, Suzanne R Pfeffer   +6 more
doaj   +1 more source

In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa [PDF]

, 2015
The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required.
Bragonzi, Alessandra, Fernandez Pinar, Regina, Imperi, Francesco, LO SCIUTO, Alessandra, Ranucci, Serena, Rossi, Alice   +5 more
core   +1 more source

Skin morphology of the mutant hairless USP mouse

Brazilian Journal of Medical and Biological Research, 2005
The morphology of the skin of the mutant hairless USP mouse was studied by histological, histochemical and immunohistochemical methods and compared to the skin of BALB/c mice.
S.M.G. Massironi, M.R. Giacóia, P.C. Maiorka, T.L. Kipnis, M.L.Z. Dagli   +4 more
doaj   +1 more source

The Mutation of the Genes Related to Neurovirulence in HSV-2 Produces an Attenuated Phenotype in Mice

Viruses, 2020
HSV-2 (Herpes simplex virus type 2) is a critical viral agent that mainly causes genital herpes and life-long latent infection in the dorsal root ganglia.
Lei Liu, Jishuai Cheng, Tangwei Mou, Ying Zhang, Xingli Xu, Jingjing Zhang, Xueqi Li, Xiao Feng, Xiangxiong Xu, Yun Liao, Shengtao Fan, Lichun Wang, Guorun Jiang, Qihan Li   +13 more
doaj   +1 more source

A live attenuated RHΔompdcΔuprt mutant of Toxoplasma gondii induces strong protective immunity against toxoplasmosis in mice and cats

Infectious Diseases of Poverty, 2023
Background Toxoplasma gondii is an obligate intracellular apicomplexan parasite and is responsible for zoonotic toxoplasmosis. It is essential to develop an effective anti-T.
Yu Shen, Bin Zheng, Hao Sun, Songrui Wu, Jiyuan Fan, Jianzu Ding, Meng Gao, Qingming Kong, Di Lou, Haojie Ding, Xunhui Zhuo, Shaohong Lu   +11 more
doaj   +1 more source

Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection [PDF]

, 2017
Urinary tract infections: targeting enzymes might help Identifying bacterial and host enzymes that support biofilm formation may help prevent urinary tract infections caused by catheters.
Caparon, Michael G, Cusumano, Zachary T, Flores-Mireles, Ana L, Hultgren, Scott J, Takagi, Enzo, Xu, Wei   +5 more
core   +3 more sources

Protective immunity elicited by oral immunization of mice with Salmonella enterica serovar Typhimurium Braun lipoprotein (Lpp) and acetyltransferase (MsbB) mutants

Frontiers in Cellular and Infection Microbiology, 2016
We evaluated the extent of attenuation and immunogenicity of the ∆lppAB and ∆lppAB ∆msbB mutants of Salmonella enterica serovar Typhimurium when delivered to mice by the oral route.
Tatiana E Erova, Michelle L Kirtley, Erc C Fitts, Duraisamy Ponnusamy, Wallace B Baze, Jourdan A Andersson, Yingzi Cong, Bethany L Tiner, Jian Sha, Ashok K Chopra   +9 more
doaj   +1 more source