Results 21 to 30 of about 252,850 (254)

Recombinant proteins A29L, M1R, A35R, and B6R vaccination protects mice from mpox virus challenge

Frontiers in Immunology, 2023
Since May 2022, mutant strains of mpox (formerly monkeypox) virus (MPXV) have been rapidly spreading among individuals who have not traveled to endemic areas in multiple locations, including Europe and the United States.
Ding Tang, Xiaoke Liu, Jia Lu, Huifen Fan, Xiuli Xu, Kaili Sun, Ruyu Wang, Chunyang Li, Demiao Dan, Hongqiao Du, Zejun Wang, Xinguo Li, Xiaoming Yang   +12 more
doaj   +1 more source

Competence-induced protein Ccs4 facilitates pneumococcal invasion into brain tissue and virulence in meningitis

Virulence, 2018
Streptococcus pneumoniae is a major pathogen that causes pneumonia, sepsis, and meningitis. The candidate combox site 4 (ccs4) gene has been reported to be a pneumococcal competence-induced gene. Such genes are involved in development of S.
Yujiro Hirose, Masaya Yamaguchi, Kana Goto, Tomoko Sumitomo, Masanobu Nakata, Shigetada Kawabata   +5 more
doaj   +1 more source

Altered cellular infiltration and cytokine levels during early Mycobacterium tuberculosis sigC mutant infection are associated with late-stage disease attenuation and milder immunopathology in mice

BMC Microbiology, 2008
Background Mouse virulence assessments of certain Mycobacterium tuberculosis mutants have revealed an immunopathology defect in which high tissue CFU counts are observed but the tissue pathology and lethality are reduced. M.
McMurray David N, Geiman Deborah E, Converse Paul J, Ly Lan H, Abdul-Majid Khairul-Bariah, Bishai William R   +5 more
doaj   +1 more source

A Carbamoyl Phosphate Synthetase II (CPSII) Deletion Mutant of Toxoplasma gondii Induces Partial Protective Immunity in Mice

Frontiers in Microbiology, 2021
Toxoplasma gondii is an obligate intracellular protozoan parasite. T. gondii primarily infection in pregnant women may result in fetal abortion, and infection in immunosuppressed population may result in toxoplasmosis.
Xunhui Zhuo, Kaige Du, Kaige Du, Haojie Ding, Di Lou, Bin Zheng, Shaohong Lu   +6 more
doaj   +1 more source

Functional plasticity in the type IV secretion system of Helicobacter pylori. [PDF]

, 2012
Helicobacter pylori causes clinical disease primarily in those individuals infected with a strain that carries the cytotoxin associated gene pathogenicity island (cagPAI).
Barrozo, Roberto M, Cariaga, Taryn A, Cooke, Cara L, Cover, Timothy L, Gaddy, Jennifer A, Hansen, Lori M, Johnson, Elizabeth M, Lam, Anna M, Peek, Richard M, Solnick, Jay V, Suarez, Giovanni   +10 more
core   +1 more source

Quantitative analysis of mouse urine volatiles: in search of MHC-dependent differences. [PDF]

PLoS ONE, 2007
Genes of the major histocompatibility complex (MHC), which play a critical role in immune recognition, influence mating preference and other social behaviors in mice.
Frank Röck, Karl-Peter Hadeler, Hans-Georg Rammensee, Peter Overath   +3 more
doaj   +1 more source

Loss of very-long O-antigen chains optimizes capsule-mediated immune evasion by Salmonella enterica serovar Typhi. [PDF]

, 2013
UnlabelledExpression of capsular polysaccharides is a variable trait often associated with more-virulent forms of a bacterial species. For example, typhoid fever is caused by the capsulated Salmonella enterica serovar Typhi, while nontyphoidal Salmonella
Bäumler, Andreas J, Crawford, Robert W, Spees, Alanna M, Tsolis, Renée M, Wangdi, Tamding, Xavier, Mariana N   +5 more
core   +1 more source

Virulence of Mycobacterium tuberculosis after Acquisition of Isoniazid Resistance: Individual Nature of katG Mutants and the Possible Role of AhpC. [PDF]

PLoS ONE, 2016
In the last decade, there were 10 million new tuberculosis cases per year globally. Around 9.5% of these cases were caused by isoniazid resistant (INHr) Mycobacterium tuberculosis (Mtb) strains.
Luisa Maria Nieto R, Carolina Mehaffy, Elizabeth Creissen, JoLynn Troudt, Amber Troy, Helle Bielefeldt-Ohmann, Marcos Burgos, Angelo Izzo, Karen M Dobos   +8 more
doaj   +1 more source

Attenuation of virulence in multiple serotypes (M1, M3, and M28) of Group A Streptococcus after the loss of secreted esterase

Journal of Microbiology, Immunology and Infection, 2022
Introduction: Group A Streptococcus (GAS) can produce streptococcal secreted esterase (Sse), which inhibits neutrophil recruitment to the site of infection and is crucial for GAS pathogenesis.
Xiaolan Zhang, Yuan Zhao, Yue Wang, Minghui Cai, Yingli Song, Hui Zhu   +5 more
doaj   +1 more source

DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice. [PDF]

, 2020
Although thousands of genetically modified mouse strains have been cryopreserved by sperm freezing, the likelihood of cryorecovery success cannot be accurately predicted using conventional sperm parameters.
Li, Ming-Wen, Lloyd, KC Kent
core   +1 more source