Results 21 to 30 of about 256,488 (286)

Protective immunity elicited by oral immunization of mice with Salmonella enterica serovar Typhimurium Braun lipoprotein (Lpp) and acetyltransferase (MsbB) mutants

Frontiers in Cellular and Infection Microbiology, 2016
We evaluated the extent of attenuation and immunogenicity of the ∆lppAB and ∆lppAB ∆msbB mutants of Salmonella enterica serovar Typhimurium when delivered to mice by the oral route.
Tatiana E Erova, Michelle L Kirtley, Erc C Fitts, Duraisamy Ponnusamy, Wallace B Baze, Jourdan A Andersson, Yingzi Cong, Bethany L Tiner, Jian Sha, Ashok K Chopra   +9 more
doaj   +1 more source

Recombinant proteins A29L, M1R, A35R, and B6R vaccination protects mice from mpox virus challenge

Frontiers in Immunology, 2023
Since May 2022, mutant strains of mpox (formerly monkeypox) virus (MPXV) have been rapidly spreading among individuals who have not traveled to endemic areas in multiple locations, including Europe and the United States.
Ding Tang, Xiaoke Liu, Jia Lu, Huifen Fan, Xiuli Xu, Kaili Sun, Ruyu Wang, Chunyang Li, Demiao Dan, Hongqiao Du, Zejun Wang, Xinguo Li, Xiaoming Yang   +12 more
doaj   +1 more source

Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model [PDF]

, 2019
Background: Campylobacter jejuni infections constitute serious threats to human health with increasing prevalences worldwide. Our knowledge regarding the molecular mechanisms underlying host-pathogen interactions is still limited.
Backert, Steffen, Bereswill, Stefan, Boehm, Manja, Escher, Ulrike, Heimesaat, Markus M., Mousavi, Soraya, Schmidt, Anna-Maria, Tegtmeyer, Nicole   +7 more
core   +4 more sources

Altered cellular infiltration and cytokine levels during early Mycobacterium tuberculosis sigC mutant infection are associated with late-stage disease attenuation and milder immunopathology in mice

BMC Microbiology, 2008
Background Mouse virulence assessments of certain Mycobacterium tuberculosis mutants have revealed an immunopathology defect in which high tissue CFU counts are observed but the tissue pathology and lethality are reduced. M.
McMurray David N, Geiman Deborah E, Converse Paul J, Ly Lan H, Abdul-Majid Khairul-Bariah, Bishai William R   +5 more
doaj   +1 more source

Competence-induced protein Ccs4 facilitates pneumococcal invasion into brain tissue and virulence in meningitis

Virulence, 2018
Streptococcus pneumoniae is a major pathogen that causes pneumonia, sepsis, and meningitis. The candidate combox site 4 (ccs4) gene has been reported to be a pneumococcal competence-induced gene. Such genes are involved in development of S.
Yujiro Hirose, Masaya Yamaguchi, Kana Goto, Tomoko Sumitomo, Masanobu Nakata, Shigetada Kawabata   +5 more
doaj   +1 more source

Quantitative analysis of mouse urine volatiles: in search of MHC-dependent differences. [PDF]

PLoS ONE, 2007
Genes of the major histocompatibility complex (MHC), which play a critical role in immune recognition, influence mating preference and other social behaviors in mice.
Frank Röck, Karl-Peter Hadeler, Hans-Georg Rammensee, Peter Overath   +3 more
doaj   +1 more source

A Carbamoyl Phosphate Synthetase II (CPSII) Deletion Mutant of Toxoplasma gondii Induces Partial Protective Immunity in Mice

Frontiers in Microbiology, 2021
Toxoplasma gondii is an obligate intracellular protozoan parasite. T. gondii primarily infection in pregnant women may result in fetal abortion, and infection in immunosuppressed population may result in toxoplasmosis.
Xunhui Zhuo, Kaige Du, Kaige Du, Haojie Ding, Di Lou, Bin Zheng, Shaohong Lu   +6 more
doaj   +1 more source

Dynamic interactions of a conserved enterotoxigenic Escherichia coli adhesin with intestinal mucins govern epithelium engagement and toxin delivery [PDF]

, 2016
At present, there is no vaccine for enterotoxigenic Escherichia coli (ETEC), an important cause of diarrheal illness. Nevertheless, recent microbial pathogenesis studies have identified a number of molecules produced by ETEC that contribute to its ...
Bhullar, Kirandeep, Fleckenstein, James M, Kuhlmann, F. Matthew, Kumar, Pardeep, Luo, Qingwei, Vallance, Bruce A, Xia, Lijun, Yang, Hyungjun   +7 more
core   +2 more sources

An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]

, 2005
Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Buxton, RS, Colston, MJ, Curry, JM, Gohil, K, Hunt, DM, Rickman, L, Smerdon, SJ, Strom, M, Whalan, R   +8 more
core   +2 more sources

Mouse models of colorectal cancer. [PDF]

, 2011
Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip, Tong, Yunguang, Yang, Wancai   +2 more
core   +2 more sources