Results 101 to 110 of about 239,216 (213)

Obesity, Diabetes and Leptin: Lessons Learned from Obese Hyperclycemic Mice

Ibrahim Medical College Journal, 1970
The recent epidemic nature of obesity and association of obesity with the development of type 2 diabetes demands dissection of the pathophysiology of this morbid disorder which is essential for better understanding of the process of evolution of insulin resistance.
openaire   +3 more sources

Sickness behavior in obese mice

, 2022
The consumption of a hypercaloric diet leads to an increase in obesity, which can lead to an inflammatory state. Thus, the objective of this work was to analyze the influence of this inflammation on the behavior of obese animals. For this, male Swiss mice were kept under controlled feeding were divided into 2 groups; Group Cafeteria diet, which ...
Nones, Débora Cristina da Cunha, Kalil-Cutti, Bruna, Paiva, Alexandre Giusti, Giusti, Fabiana Cardoso Vilela   +3 more
openaire   +1 more source

Cre/lox generation of a novel whole-body Kiss1r KO mouse line recapitulates a hypogonadal, obese, and metabolically-impaired phenotype. [PDF]

, 2019
Kisspeptin and its receptor, Kiss1r, act centrally to stimulate reproduction. Recent evidence indicates that kisspeptin is also important for body weight and metabolism, as whole-body Kiss1r KO mice, developed with gene trap technology, display obesity ...
Kauffman, Alexander S, Marooki, Nuha, Smith, Jeremy T, Tolson, Kristen P, Wolfe, Andrew   +4 more
core   +1 more source

Shift Work: Gut Health and Metabolic Disease [PDF]

, 2020
The number of people engaged in shift work continues to rise, and with it the research linking shift work to various diseases and conditions. Shift work changes the body’s sleeping patterns and circadian rhythms which has an effect on all parts of the ...
Lane, Hailey
core   +1 more source

Different Effects of Obesity and Fasting on the Expression of Type 3 Deiodinase and Thyroid Hormone Receptors in the Liver and Visceral Adipose Tissue of C57BL/6 Male Mice

Indian Journal of Endocrinology and Metabolism
Introduction: Energy status can alter thyroid hormone signalling in different tissues. Little is known about the effect of fasting on the local thyroid hormone metabolism under high-fat diet (HFD)-induced obesity.
Alireza Muazzez, Ghazaleh Shimi, Farinaz H. Balam, Arman Ghorbani, Hamid Zand   +4 more
doaj   +1 more source

Mouse circadian plasma leptin and active ghrelin rhythms under ad libitum and scheduled feeding [PDF]

, 2007
Thesis (M.S.) University of Alaska Fairbanks, 2007Light is the strongest timing cue for the circadian system, but non-photic cues can also entrain the master circadian clock, i.e., suprachiasmatic nuclei (SCN).
Wan, Haiting
core  

Impaired Autophagic Flux in Adipose Tissue Aggravates Pancreatic Injury in Obesity-Related Severe Acute Pancreatitis. [PDF]

Immun Inflamm Dis
Sheng LP, Shang GC, Han CQ, Ling X, Guo XW, Lin R, Ding Z.   +6 more
europepmc   +1 more source

Weight Loss During Obesity Provokes Asparaginase-Associated Liver Steatosis and Endoplasmic Reticulum Stress. [PDF]

FASEB J
Bhavsar CT, Zalma BA, Tomoo K, Zhang Y, Lopez EM, Mirek ET, Dixon JL, Henderson GC, Wek RC, Anthony TG.   +9 more
europepmc   +1 more source

Evexomostat (SDX-7320), a methionine aminopeptidase type 2 inhibitor, stimulates weight loss and inhibits obesity-accelerated tumor growth. [PDF]

Front Oncol
Cornelius P, Mayes BA, Dannenberg AJ, Dufour PJ, Little S, Guzior DV, Petersen JS, Shanahan JM, Carver BJ.   +8 more
europepmc   +1 more source

Expansion of bone marrow adipocytes in obese mice leads to PD-L1-driven bone marrow immunosuppression and osteoclastogenesis. [PDF]

Bone Res
Costa SN, Chlebek C, Gray L, Caradonna P, Ryzhov S, Rosen CJ.   +5 more
europepmc   +1 more source