Results 41 to 50 of about 239,216 (213)
Frontiers in Physiology, 2020 Obesity has been described as a major factor of health risk in modern society. Next to intricately linked comorbidities like coronary artery disease or diabetes, an influence of obesity on regeneration after muscle injury has been described previously ...
Adrian Gihring +6 more
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Does a nephron deficit exacerbate the renal and cardiovascular effects of obesity? [PDF]
PLoS ONE, 2013 It has been hypothesized that a reduced nephron endowment exacerbates the hypertensive and renal effects of obesity. We therefore examined the impact of diet-induced obesity on renal structure and function, and arterial pressure in a genetic model of ...
Seshini Gurusinghe +6 more
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Metabolic Effects of Bariatric Surgery in Mouse Models of Circadian Disruption [PDF]
, 2015 Background/Objectives: Mounting evidence supports a link between circadian disruption and metabolic disease. Humans with circadian disruption (for example, night-shift workers) have an increased risk of obesity and cardiometabolic diseases compared with ...
Arble, Deanna M. +4 more
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Hepatic Runx1t1 improves body fat index after endurance exercise in obese mice
Scientific Reports, 2023 Endurance exercise could attenuate obesity induced by high fat diet (HFD). Thus, the purpose of this study was to explore the crucial targets that play key roles in the improvement of body fat index (BFI) in obese mice by endurance exercise.
Ning Jiang +7 more
doaj +1 more source
High fat diet causes rebound weight gain [PDF]
, 2012 Acknowledgements This work was funded by a grant from Action Medical Research (SP4581).
McNay, David E. G., Speakman, John R.
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The Bidirectional Relationship Between Obstructive Sleep Apnea and Metabolic Disease [PDF]
, 2018 Obstructive sleep apnea (OSA) is a common sleep disorder, effecting 17% of the total population and 40–70% of the obese population (1, 2). Multiple studies have identified OSA as a critical risk factor for the development of obesity, diabetes, and ...
Arble, Deanna M., Framnes, Sarah N.
core +10 more sources
Spontaneous restoration of functional β‐cell mass in obese SM/J mice
Physiological Reports, 2020 Maintenance of functional β‐cell mass is critical to preventing diabetes, but the physiological mechanisms that cause β‐cell populations to thrive or fail in the context of obesity are unknown.
Mario A. Miranda +8 more
doaj +1 more source
Thrombospondin1 deficiency attenuates obesity-associated microvascular complications in ApoE-/- mice. [PDF]
PLoS ONE, 2015 Obesity is associated with insulin resistance and the increased development of vascular complications. Previously, we have demonstrated that thrombospondin1 (TSP1) regulates macrophage function and contributes to obesity associated inflammation and ...
Hasiyeti Maimaitiyiming +4 more
doaj +1 more source
Gut Microbes, 2022 Obesity causes chronic inflammation and changes in gut microbiome. However, how this contributes to poor survival and therapy resistance in patients with pancreatic cancer remain undetermined.
Kousik Kesh +10 more
doaj +1 more source
Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress [PDF]
, 2018 Aim. Nonalcoholic steatohepatitis (NASH) is the consequence of insulin resistance, fatty acid accumulation, oxidative stress, and lipotoxicity.We hypothesize that an increase in the inflammatory adipokine NOV decreases antioxidant Heme Oxygenase 1 (HO- 1)
Abraham, Nader G. +13 more
core +1 more source