Results 21 to 30 of about 103,942 (288)

Complex Polymeric Architectures Self-Assembling in Unimolecular Micelles: Preparation, Characterization and Drug Nanoencapsulation

Pharmaceutics, 2018
Unimolecular polymeric micelles are a class of single-molecule amphiphilic core-shell polymeric architectures, where the hydrophobic core is well stabilized by the hydrophilic shell, avoiding intermolecular core-core interactions.
Stefania Ordanini, Francesco Cellesi
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Poly(ethylene glycol)-sheddable reduction-sensitive polyurethane micelles for triggered intracellular drug delivery for osteosarcoma treatment

Journal of Orthopaedic Translation, 2020
Background: The survival rate of osteosarcoma therapy still lags behind overall cancer therapies due to the intrinsic or acquired drug resistance.
Zhengjie Yang, Qianping Guo, Yan Cai, Xuesong Zhu, Caihong Zhu, Yuling Li, Bin Li   +6 more
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CKAP4 Antibody-Conjugated Si Quantum Dot Micelles for Targeted Imaging of Lung Cancer

Nanoscale Research Letters, 2021
At present, various fluorescent nanomaterials have been designed and synthesized as optical contrast agents for surgical navigation. However, there have been no reports on the preparation of fluorescent contrast agents for lung cancer surgery navigation ...
Xin Huang, Qian Chen, Xin Li, Chenyu Lin, Kun Wang, Cici Luo, Wenjun Le, Xiaodong Pi, Zhongmin Liu, Bingdi Chen   +9 more
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Preparation and In Vitro and In Vivo Antitumor Effects of VEGF Targeting Micelles

Technology in Cancer Research & Treatment, 2020
Background: Doxorubicin (DOX) has antitumor effects mediated by cell viability inhibition and by inducing cellular apoptosis. However, it has limited use in clinical applications due to various factors such as hydrophobicity, dose-dependent toxicity ...
Jing Chang MD, Zhe Yang BD, Junfeng Li MD, Yufen Jin MD, Yihang Gao MD, Yanwen Sun MD, Hainan Li MD, Ting Yu PhD   +7 more
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Comparison of hyaluronic acid-based micelles and polyethylene glycol-based micelles on reversal of multidrug resistance and enhanced anticancer efficacy in vitro and in vivo

Drug Delivery, 2018
Polyethylene glycol (PEG)-based block copolymer micelles and hyaluronic acid (HA)-based grafted copolymer micelles have been widely investigated in chemotherapy.
Jinling Wang, Ying Li, Lifang Wang, Xiaohui Wang, Pengfei Tu   +4 more
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Preparation and Physicochemical Characterization of Biodegradable mPEG-PCL Core-Shell Micelles for Delivery of Artemisinin

Pharmaceutical Sciences, 2016
Background: Artemisinin is a sesquiterpene lactone chemical extract from Artemisia annua, is poorly resolvable in water and a fast-acting blood active in treating the acute attack of malaria. Methods: Artemisinin was encapsulated within mPEG-PCL micelles
Hamid Reza Kheiri Manjili 1, Hojjat Malvandi 3, Mir-Sajjad Mosavi 1, Hossein Danafar 2,3 *
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Poloxamer-188 and d-α-Tocopheryl Polyethylene Glycol Succinate (TPGS-1000) Mixed Micelles Integrated Orodispersible Sublingual Films to Improve Oral Bioavailability of Ebastine; In Vitro and In Vivo Characterization

Pharmaceutics, 2021
Orodispersible sublingual films (OSFs) composed of hydrophilic polymers were loaded with poloxamer-188 and d-α-tocopheryl polyethylene glycol succinate (TPGS-1000) mixed micelles to improve the oral bioavailability of a poorly soluble drug, ebastine (EBT)
Nayyer Islam, Muhammad Irfan, Salah-Ud-Din Khan, Haroon Khalid Syed, Muhammad Shahid Iqbal, Ikram Ullah Khan, Amina Mahdy, Mohamed Raafat, Mohammad Akbar Hossain, Sana Inam, Rabia Munir, Memoona Ishtiaq   +11 more
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MICELLIZATION OF CASEIN-DEXSTRAN STRUCTURES OBTAINED IN THE MAILLARD REACTION

Вестник Северо-Кавказского федерального университета, 2022
Micelles were prepared by the crosslinking copolymerization of casein and dextran in the Maillard reaction. Glycated proteins were identified using ft-IR spectrometry.
Roman Budkevich, Anastasiya Eremina, Elena Budkevich, Gennady Slyusarev   +3 more
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Multi-Functional Drug Carrier Micelles With Anti-inflammatory Drug

Frontiers in Chemistry, 2019
The multi-functional micelles poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide-co-10 undecanoic acid)/CM-Dextran Fe3O4 (PNDU/CM-Dex Fe3O4) were poly (NIPAAm-co-DMAAm-co-UA) (PNDU) grafting hydrophilic CM-Dextran Fe3O4 which possess pH-dependent ...
Wei-Jie Wang, Wei-Jie Wang, Yin-Chou Huang, Chao-Ming Su, Tzong-Rong Ger   +4 more
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Novel ultra-small micelles based on ginsenoside Rb1: a potential nanoplatform for ocular drug delivery

Drug Delivery, 2019
Objectives: Ginsenosides Rb1 (Rb1) could form micelles in aqueous solutions. Self-assembled Rb1 micelles could potentially be utilized as ocular drug delivery system, and it was postulated that the encapsulation of a medicine within Rb1 micelles might ...
Mengshuang Li, Jie Lan, Xuefei Li, Meng Xin, Hui Wang, Fan Zhang, Xiaohong Lu, Zengfang Zhuang, Xianggen Wu   +8 more
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