“Anti-Michael addition” of Grignard reagents to sulfonylacetylenes: synthesis of alkynes [PDF]
, 2017 In this work, the addition of Grignard reagents to arylsulfonylacetylenes, which undergoes an “anti-Michael addition”, resulting in their alkynylation under very mild conditions is described.
Alemán, José +4 more
core +2 more sources
The applicability of sulfoxide Michael acceptor – 2-(S)-[(4-methylphenyl)sulfinyl]-2-cyclopenten-1-one in constructing the carbon skeleton of 9,11-secosterols [PDF]
Proceedings of the Estonian Academy of SciencesA possibility of use of the Michael addition reaction of the A,BÂ-ring fragment enolate to sulfoxide 2Â-(S)-Â[(4Â-methylphenyl)sulfinyl]-Â2Â-cyclopentenÂ-1Â-one for constructing the main skeleton of 9,11Â-secosterols was studied.
Kristi Rõuk +3 more
doaj +1 more source
Microwave assisted synthesis of some new coumarin-pyrazoline hybrids and their antimicrobial activity [PDF]
Journal of the Serbian Chemical Society, 2015 A series of pyrazolines 4a-g have been synthesized by Michael addition of chalcones 3a-g with hydrazine hydrate in presence of sodium acetate under conventional heating and microwave irradiation.
Ashok Dongamanti +3 more
doaj +1 more source
Poly(amidoamine)-BSA conjugates synthesised by Michael addition reaction retained enzymatic activity [PDF]
, 2016 Polymer-protein conjugates are key to overcome some of the therapeutic protein limitations, including inefficient intracellular delivery. Poly(amidoamine)s are bioresponsive polyelectrolytes, which can form complexes with proteins and promote their ...
Abuchowski +54 more
core +1 more source
4′-(N-(2-Cyanoethyl)pyrrol-2-yl)-2,2′:6′,2″-terpyridine
Molbank, 2023 The preparation and characterization of a new multi-functionalized terpyridine molecule featuring a pyrrole heterocycle and a cyano group is described. This new compound was obtained via a KF/alumina-catalyzed Michael addition of 4′-(pyrrol-2-yl)-2,2′:6′,
Jérôme Husson
doaj +1 more source
Enantioselective Organocatalytic Double Michael Addition Reactions [PDF]
Organic Letters, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Hao, Li +5 more
openaire +2 more sources
Synthesis of interesting β-nitrohydrazides through a thiourea organocatalysed aza-Michael addition [PDF]
, 2014 The synthesis of antimicrobial β-nitrohydrazides, as the target product of our reaction, is reached for the first time under organocatalytic enantioselective conditions.
Alcaine, Ana +2 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Chemotherapy‐induced peripheral neuropathy remains a major complication in pediatric cancer, with disrupted somatosensory and nociceptive processing being a key aspect. This review synthesizes empirical studies on alterations in somatosensory and nociceptive processing in children and adolescents with cancer.
Julia Schweiger +4 more
wiley +1 more source
How Dihalogens Catalyze Michael Addition Reactions [PDF]
Angewandte Chemie International Edition, 2019 AbstractWe have quantum chemically analyzed the catalytic effect of dihalogen molecules (X2=F2, Cl2, Br2, and I2) on the aza‐Michael addition of pyrrolidine and methyl acrylate using relativistic density functional theory and coupled‐cluster theory. Our state‐of‐the‐art computations reveal that activation barriers systematically decrease as one goes to
Trevor A. Hamlin +2 more
openaire +4 more sources
Synthesis of 1,2,3-triazole functionalized hyperbranched poly(ethyleneimine) and its use as multifunctional anionic macroinitiator for diglycidyl ether of bisphenol A curing [PDF]
, 2016 Hyperbranched poly(ethyleneimine) (PEI) has been modified by the addition of propargyl acrylate following a Michael addition reaction. On this polymer (PEI-yne) a copper (I)-catalyzed azide alkyne cycloaddition (CuAAC) has been performed to obtain a ...
Acebo Gorostiza, Cristina +4 more
core +2 more sources