Results 31 to 40 of about 724,095 (330)

Analysing Microarray Data using the Multi-functional Immune Ontologiser

open access: yesJournal of Integrative Bioinformatics, 2006
Gene expression microarrays are a prominent experimental tool in functional genomics allowing researchers to gain a deeper understanding of biological processes.
Khalid Sabah   +4 more
doaj   +1 more source

Crosstalk between Receptor and Non-receptor Mediated Chemical Modes of Action in Rat Livers Converges through a Dysregulated Gene Expression Network at Tumor Suppressor Tp53

open access: yesFrontiers in Genetics, 2017
Chemicals, toxicants, and environmental stressors mediate their biologic effect through specific modes of action (MOAs). These encompass key molecular events that lead to changes in the expression of genes within regulatory pathways.
Karen M. Funderburk   +3 more
doaj   +1 more source

Coupled Two-Way Clustering Analysis of Gene Microarray Data [PDF]

open access: yes, 2000
We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant partitions emerge ...
Alizadeh   +12 more
core   +4 more sources

Cytology Microarrays

open access: yesAnalytical Cellular Pathology, 2007
The use of high throughput genetic and expression platforms are generating many candidate diagnostic markers and therapeutic targets for a wide variety of clinical conditions. Tissue microarrays can be used for the evaluation of the utility of many of these markers.
J. Korbelik   +4 more
openaire   +3 more sources

Cleaning the Medicago Microarray Database to Improve Gene Function Analysis

open access: yesPlants, 2021
Transcriptomics studies have been facilitated by the development of microarray and RNA-Seq technologies, with thousands of expression datasets available for many species.
Francesca Marzorati   +4 more
doaj   +1 more source

TmaDB: a repository for tissue microarray data [PDF]

open access: yes, 2005
Background: Tissue microarray (TMA) technology has been developed to facilitate large, genome-scale molecular pathology studies. This technique provides a high-throughput method for analyzing a large cohort of clinical specimens in a single experiment ...
Quirke, P, Sharma-Oates, A, Westhead, DR
core   +3 more sources

Pulmonary MicroRNA Changes Alter Angiogenesis in Chronic Obstructive Pulmonary Disease and Lung Cancer

open access: yesBiomedicines, 2021
The pulmonary endothelium is dysfunctional in chronic obstructive pulmonary disease (COPD), a known risk factor for lung cancer. The pulmonary endothelium is altered in emphysema, which is disproportionately affected by cancers.
Clara E. Green   +3 more
doaj   +1 more source

Protein Microarrays [PDF]

open access: yes, 2009
Protein microarrays containing nearly the entire yeast proteome have been constructed. They are typically prepared by overexpression and high-throughput purification and printing onto microscope slides. The arrays can be used to screen nearly the entire proteome in an unbiased fashion and have enormous utility for a variety of applications.
Fasolo, Joseph, Snyder, Michael
openaire   +2 more sources

Gut Microbiota as an Epigenetic Regulator: Pilot Study Based on Whole-Genome Methylation Analysis

open access: yesmBio, 2014
The core human gut microbiota contributes to the developmental origin of diseases by modifying metabolic pathways. To evaluate the predominant microbiota as an epigenetic modifier, we classified 8 pregnant women into two groups based on their dominant ...
Himanshu Kumar   +6 more
doaj   +1 more source

Compressive Sensing DNA Microarrays [PDF]

open access: yes, 2008
Compressive sensing microarrays (CSMs) are DNA-based sensors that operate using group testing and compressive sensing (CS) principles. In contrast to conventional DNA microarrays, in which each genetic sensor is designed to respond to a single target, in
Baraniuk, RG   +3 more
core   +1 more source

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