Results 31 to 40 of about 515,000 (271)

Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc

open access: yeseLife, 2018
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Blum et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Transcriptional amplification in tumor cells with elevated c ...
L Michelle Lewis   +6 more
doaj   +1 more source

Minimum Information About a Microarray Experiment (MIAME) – Successes, Failures, Challenges

open access: yesThe Scientific World Journal, 2009
The Minimum Information About a Microarray Experiment (known as MIAME) guidelines describe information that needs to be provided to enable the interpretation of the results of a microarray-based experiment unambiguously.
Alvis Brazma
doaj   +1 more source

Seasonal dynamics of DNA and RNA viral bioaerosol communities in a daycare center

open access: yesMicrobiome, 2019
Background Viruses play an important role in ecosystems, including the built environment (BE). While numerous studies have characterized bacterial and fungal microbiomes in the BE, few have focused on the viral microbiome (virome).
Aaron J. Prussin   +6 more
doaj   +1 more source

Microarray Data Analysis: From Hypotheses to Conclusions Using Gene Expression Data

open access: yesCellular Oncology, 2004
We review several commonly used methods for the design and analysis of microarray data. To begin with, some experimental design issues are addressed.
Nicola J. Armstrong, Mark A. van de Wiel
doaj   +1 more source

The Application of Microfluidic Technologies in Aptamer Selection

open access: yesFrontiers in Cell and Developmental Biology, 2021
Aptamers are sequences of single-strand oligonucleotides (DNA or RNA) with potential binding capability to specific target molecules, which are increasingly used as agents for analysis, diagnosis, and medical treatment.
Yang Liu   +14 more
doaj   +1 more source

GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox1[w]

open access: yesPlant Physiology, 2004
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web ...
Philip Zimmermann   +3 more
semanticscholar   +1 more source

Blood‐derived DNA methylation predictors of mortality discriminate tumor and healthy tissue in multiple organs

open access: yesMolecular Oncology, 2020
Evidence has shown that certain methylation markers derived from blood can mirror corresponding methylation signatures in internal tissues. In the current study, we aimed to investigate two strong epigenetic predictors for life span, derived from blood ...
Yan Zhang   +6 more
doaj   +1 more source

Comment: Microarrays, Empirical Bayes and the Two-Group Model [PDF]

open access: yesStatistical Science 2008, Vol. 23, No. 1, 29-33, 2008
Comment on ``Microarrays, Empirical Bayes and the Two-Group Model'' [arXiv:0808.0572]
arxiv   +1 more source

Breakthrough Solution for Antimicrobial Resistance Detection: Surface‐Enhanced Raman Spectroscopy‐based on Artificial Intelligence

open access: yesAdvanced Materials Interfaces, EarlyView., 2023
This review discusses the use of Surface‐Enhanced Raman Spectroscopy (SERS) combined with Artificial Intelligence (AI) for detecting antimicrobial resistance (AMR). Various SERS studies used with AI techniques, including machine learning and deep learning, are analyzed for their advantages and limitations.
Zakarya Al‐Shaebi   +4 more
wiley   +1 more source

Registered report: Transcriptional amplification in tumor cells with elevated c-Myc

open access: yeseLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
David Blum   +3 more
doaj   +1 more source

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