Results 21 to 30 of about 346,542 (364)
This study investigated genotypic and phenotypic antimicrobial resistance profiles, phylogenic relatedness, plasmid and virulence composition of 39 Salmonella enterica strains isolated from chicken meat samples using whole genome sequencing (WGS ...
Khaloud O. Alzahrani+17 more
doaj +1 more source
Coupled environmental and demographic fluctuations shape the evolution of cooperative antimicrobial resistance [PDF]
There is a pressing need to better understand how microbial populations respond to antimicrobial drugs, and to find mechanisms to possibly eradicate antimicrobial-resistant cells. The inactivation of antimicrobials by resistant microbes can often be viewed as a cooperative behavior leading to the coexistence of resistant and sensitive cells in large ...
arxiv +1 more source
Quorum-Sensing Regulation of Antimicrobial Resistance in Bacteria
Quorum sensing is a cell-to-cell communication system that exists widely in the microbiome and is related to cell density. The high-density colony population can generate a sufficient number of small molecule signals, activate a variety of downstream ...
Xihong Zhao, Zixuan Yu, Tian Ding
doaj +1 more source
From environment to clinic: the role of pesticides in antimicrobial resistance
Antimicrobial resistance (AMR) in pathogens has been associated mainly with excessive use of antibiotics. Most studies of resistance have focused on clinical pathogens; however, microorganisms are exposed to numerous anthropogenic substances. Few studies
Jeadran N. Malagón-Rojas+2 more
doaj +1 more source
Overcoming Multidrug Resistance of Antibiotics via Nanodelivery Systems
Antibiotic resistance has become a threat to microbial therapies nowadays. The conventional approaches possess several limitations to combat microbial infections.
Mohammad Imran+13 more
doaj +1 more source
Eco-evolutionary dynamics of cooperative antimicrobial resistance in a population of fluctuating volume and size [PDF]
Antimicrobial resistance to drugs (AMR), a global threat to human and animal health, is often regarded as resulting from cooperative behaviour. Moreover, microbes generally evolve in volatile environments that, together with demographic fluctuations (birth and death events), drastically alter population size and strain survival.
arxiv +1 more source
Open Droplet Microfluidics for Testing Multi-Drug Resistance and Antibiotic Resilience in Bacteria [PDF]
New combinations of existing antibiotics are being investigated to combat bacterial resilience. This requires detection technologies with reasonable cost, accuracy, resolution, and throughput. Here, we present a multi -drug screening platform for bacterial cultures by combining droplet microfluidics, search algorithms, and imaging with a wide field of ...
arxiv +1 more source
Drug Resistance in Eukaryotic Microorganisms [PDF]
Eukaryotic microbial pathogens are major contributors to illness and death globally. Although much of their impact can be controlled by drug therapy as with prokaryotic microorganisms, the emergence of drug resistance has threatened these treatment ...
A Abdolrasouli+193 more
core +4 more sources
Coexistence of Competing Microbial Strains under Twofold Environmental Variability and Demographic Fluctuations [PDF]
Microbial populations generally evolve in volatile environments, under conditions fluctuating between harsh and mild, e.g. as the result of sudden changes in toxin concentration or nutrient abundance. Environmental variability thus shapes the long-time population dynamics, notably by influencing the ability of different strains of microorganisms to ...
arxiv +1 more source
Resistance to antibiotics is considered one of the most urgent global public health concerns. It has considerable impacts on health and the economy, being responsible for the failure to treat infectious diseases, higher morbidity and mortality rates, and
Hélène Meier+5 more
doaj +1 more source