Results 21 to 30 of about 717,320 (332)

Collateral sensitivity: An evolutionary trade‐off between antibiotic resistance mechanisms, attractive for dealing with drug‐resistance crisis

Health Science Reports, 2023
The discovery and development of antimicrobial drugs were one of the most significant advances in medicine, but the evolution of microbial resistance limited the efficiency of these drugs.
M. Yekani, R. Azargun, Simin Sharifi, Edris Nabizadeh, J. S. Nahand, Navideh Karimi Ansari, M. Y. Memar, J. Sóki   +7 more
semanticscholar   +1 more source

The Impact of Triclosan on the Spread of Antibiotic Resistance in the Environment [PDF]

, 2015
Triclosan (TCS) is a commonly used antimicrobial agent that enters wastewater treatment plants (WWTPs) and the environment. An estimated 1.1 × 105 to 4.2 × 105 kg of TCS are discharged from these WWTPs per year in the United States.
Carey, Daniel E., McNamara, Patrick J.
core   +7 more sources

Microbial Biofilm: A Review on Formation, Infection, Antibiotic Resistance, Control Measures, and Innovative Treatment

Microorganisms, 2023
Biofilm is complex and consists of bacterial colonies that reside in an exopolysaccharide matrix that attaches to foreign surfaces in a living organism. Biofilm frequently leads to nosocomial, chronic infections in clinical settings.
Satish Sharma, James Mohler, S. Mahajan, S. Schwartz, Liana Bruggemann, R. Aalinkeel   +5 more
semanticscholar   +1 more source

Drug Resistance in Eukaryotic Microorganisms [PDF]

, 2016
Eukaryotic microbial pathogens are major contributors to illness and death globally. Although much of their impact can be controlled by drug therapy as with prokaryotic microorganisms, the emergence of drug resistance has threatened these treatment ...
A Abdolrasouli, A Cassone, A Chowdhary, A Ecker, A Heinberg, A Kulshrestha, A Mbengue, A Mukherjee, A Selmecki, A Selmecki, A Trochine, AC Coelho, AF Cowman, AF Cowman, AH Fairlamb, AH Fairlamb, AJ Kazibwe, AM Abd-Alla, AM Dondorp, AM Mejia, AY Sokolova, B Chawla, B Gourbal, B Zingales, BD Alexander, BJ Kullberg, BK Kubata, BM Mony, BS Hall, BS Hall, BS McGwire, C Amaratunga, C Amaratunga, C Brochu, C Costa, C Mathieu, C Sisowath, C Wongsrichanalai, CA Morillo, CD Goodman, CF Oliva, CP Sanchez, CP Sanchez, D Begolo, D Rojo, DA Fidock, DS Guttery, DS Perlin, DW Denning, E Castanys-Munoz, E Chatelain, E Kussell, E Matovu, E Shor, E Snelders, E Snelders, E Vermeulen, E Wang, F Ariey, F Nosten, FC Odds, FE Graf, FE Graf, FJ Perez-Victoria, FJ Perez-Victoria, FJ Perez-Victoria, FM Fernandez, G Awasthi, G Blum, G Priotto, GA Canuto, GA Pankey, GM Nayyar, GW Rose, H Noedl, HL Callahan, HM Andrade, HY Sun, I Keren, I Molina, IH Cheeseman, IM Vincent, IM Vincent, IM Vincent, J Hemingway, J Robays, J Song, J Straimer, J Yuan, JA Urbina, JA Urbina, JC Dias, JC Dias, JC Munday, JC Wootton, JI Manzano, JL Nishikawa, JM Perez-Victoria, JR Franco, JW van der Linden, K El Fadili, K Lewis, K Seifert, KC Gray, KJ Kwon-Chung, KW Dantzler, L Denoeud-Ndam, L Glover, LE Cowen, LE Cowen, M Berg, M Ghorbal, M Maharjan, M Manske, M Plourde, M Rakotomanga, M Rakotomanga, M Venkatesan, M Woolhouse, M Woolhouse, MA Pfaller, MB Rogers, MC Brotherton, MD LaFleur, MD LaFleur, MK Kinga, MK Laufer, MR Perry, MR Perry, MR Perry, MT Duraisingh, MT Ferdig, N Baker, N Biyani, N Marquis, N Regev-Rudzki, N Rovira-Graells, NJ White, NR Cohen, NS Carter, O Epaulard, O Miotto, P Baiocco, P Maser, P Shaked-Mishan, P Vandeputte, P Wang, PE Verweij, PJ Hotez, PK Fyfe, PL Olliaro, PP Pyana, PY Mantel, R Kumar, R Mukhopadhyay, R Prasad, RD Cannon, S Alsford, S Decuypere, S Decuypere, S Dey, S Dey, S Imhof, S Kucharikova, S Leroux, S Mandal, S Mok, S Patterson, S Pelleau, S Pulcini, S Rijal, S Sundar, S Sundar, S Takala-Harrison, S Wyllie, S Wyllie, S Wyllie, S Wyllie, SA Flowers, SC Welburn, SD Singh, SE Kidd, SG Valderramos, SK Katiyar, SMF Murta, SR Meshnick, SR Wilkinson, TE Wellems, TE Wellems, TPC Dorlo, V Lutje, W Peters, Y Sterkers, Y Zhou   +193 more
core   +4 more sources

Next-generation sequencing and PCR technologies in monitoring the hospital microbiome and its drug resistance

Frontiers in Microbiology, 2022
The hospital environment significantly contributes to the onset of healthcare-associated infections (HAIs), which represent one of the most frequent complications occurring in healthcare facilities worldwide.
C. Cason, M. D’Accolti, I. Soffritti, S. Mazzacane, M. Comar, E. Caselli   +5 more
semanticscholar   +1 more source

Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]

, 2017
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina, Cavallo, Ilaria, Cilli, Laura, De Santis, Alessandra, Di Domenico, Enea Gino, Di Salvo, Fabiola, Ensoli, Fabrizio, Farulla, Ilaria, Gallo, Maria Teresa, La Parola, Ilaria Lesnoni, Pimpinelli, Fulvia, Pontone, Martina, Prignano, Grazia, Sperduti, Isabella, Toma, Luigi, Vespaziani, Matteo   +15 more
core   +2 more sources

Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues [PDF]

, 2000
The veterinary use of antimicrobial drugs in food producing animals may result in residues in food, that might modify the consumer gut flora. This review compares three model systems that maintain a complex flora of human origin: (i) human flora ...
Cemiglia CE, Corpet DE, Corpet DE Antibiotic residues and drug resistance in human intestinal flora, Corpet DE Antibiotic resistance from food, Corpet DE Current status of models for testing antibiotic residues, Freter R, Licht TR, Rollins LD, Tancrede C, Vollaard El   +9 more
core   +2 more sources

Accuracy of an amplicon-sequencing nanopore approach to identify variants in tuberculosis drug-resistance-associated genes

Microbial Genomics, 2021
A rapid and accurate diagnostic assay represents an important means to detect Mycobacterium tuberculosis , identify drug-resistant strains and ensure treatment success.
C. Mariner-Llicer, G. Goig, L. Zaragoza-Infante, M. Torres-Puente, L. Villamayor, D. Navarro, R. Borrás, Á. Chiner-Oms, I. Comas   +8 more
semanticscholar   +1 more source

Updates on microbial resistance to drugs

African Journal of Microbiology Research, 2012
The treatment of bacterial infections and other microbial infections is increasingly complicated by the ability of bacteria and other microbes to develop resistance to antimicrobial agents. Microbial resistance to antimicrobial agents or chemotherapeutic agents had been attributed to their ability to bypass or overcome the various mechanisms by which ...
B Oyelade, Temidayo Oluyomi Elufisan, Omotayo Opemipo Oyedara   +2 more
openaire   +2 more sources

Inactivation of the antidiabetic drug acarbose by human intestinal microbial-mediated degradation

Nature Metabolism, 2023
The antidiabetic drug acarbose is shown to be degraded by a Klebsiella species present in the human gut, which is enriched with acarbose treatment and might mediate acarbose resistance and variations in clinical efficacy observed in patients.
Jinzhong Tian, Chong Li, Zhixiang Dong, Yunpeng Yang, Jing Xing, Pei-Jun Yu, Ying Xin, Fengmei Xu, Lianwei Wang, Yahui Mu, Xiangyang Guo, Qiang Sun, Guoping Zhao, Yang Gu, G. Qin, Weihong Jiang   +15 more
semanticscholar   +1 more source