Results 1 to 10 of about 588,081 (304)

Integration of (S)-2,3-oxidosqualene enables E. coli to become Iron Man E. coli with improved overall tolerance

Biotechnology for Biofuels and Bioproducts, 2023
Background While representing a model bacterium and one of the most used chassis in biomanufacturing, performance of Escherichia coli is often limited by severe stresses. A super-robust E.
Wenjie Sun, Yun Chen, Mengkun Li, Syed Bilal Shah, Tianfu Wang, Jin Hou, Linquan Bai, Yan Feng, Zaigao Tan   +8 more
doaj   +1 more source

In vitro maturation of Toxoplasma gondii bradyzoites in human myotubes and their metabolomic characterization

Nature Communications, 2022
Bradyzoites are a quiescent form of Toxoplasma gondii enclosed in cysts during chronic infections. Here, Christiansen et al. develop a human myotube-based in vitro culture model of cysts that are infectious to mice and characterize their metabolism in ...
Céline Christiansen, Deborah Maus, Ellen Hoppenz, Mateo Murillo-León, Tobias Hoffmann, Jana Scholz, Florian Melerowicz, Tobias Steinfeldt, Frank Seeber, Martin Blume   +9 more
doaj   +1 more source

Catalytic properties and biological function of a PIWI-RE nuclease from Pseudomonas stutzeri

Bioresources and Bioprocessing, 2022
Background Prokaryotic Argonaute (pAgo) proteins are well-known oligonucleotide-directed endonucleases, which contain a conserved PIWI domain required for endonuclease activity.
Fei Huang, Xiaoyi Xu, Huarong Dong, Nuolan Li, Bozitao Zhong, Hui Lu, Qian Liu, Yan Feng   +7 more
doaj   +1 more source

Cross-Feeding between Members of Thauera spp. and Rhodococcus spp. Drives Quinoline-Denitrifying Degradation in a Hypoxic Bioreactor

mSphere, 2020
The complex bacterial community in a quinoline-degrading denitrifying bioreactor is predominated by several taxa, such as Thauera and Rhodococcus.
Xinxin Wu, Xiaogang Wu, Ji Li, Qiaoyu Wu, Yiming Ma, Weikang Sui, Liping Zhao, Xiaojun Zhang   +7 more
doaj   +1 more source

Ketogenic Diets Induced Glucose Intolerance and Lipid Accumulation in Mice with Alterations in Gut Microbiota and Metabolites

mBio, 2021
The ketogenic diet with extremely high fat and very low carbohydrate levels is very popular in society today. Although it has beneficial effects on epilepsy and neurodegenerative diseases, how ketogenic diets impact host glucose and lipid metabolism and ...
Yue Li, Xin Yang, Jing Zhang, Tianyi Jiang, Ziyi Zhang, Zhiyi Wang, Mengxue Gong, Liping Zhao, Chenhong Zhang   +8 more
doaj   +1 more source

A Xanthomonas oryzae type III effector XopL causes cell death through mediating ferredoxin degradation in Nicotiana benthamiana

Phytopathology Research, 2020
Plant pathogenic bacteria engage in an ongoing struggle for survival. Gram negative phytopathogenic prokaryotes deploy type III secretion system to deliver effector proteins into plant cells to manipulate the host cellular environment. In many cases, the
Wenxiu Ma, Xiameng Xu, Lulu Cai, Yanyan Cao, Fazal Haq, James R. Alfano, Bo Zhu, Lifang Zou, Gongyou Chen   +8 more
doaj   +1 more source

Molecular Deceleration Regulates Toxicant Release to Prevent Cell Damage in Pseudomonas putida S16 (DSM 28022)

mBio, 2020
The underlying molecular mechanisms of flavin-dependent amine oxidases remain relatively poorly understood, even though many of these enzymes have been reported.
Hongzhi Tang, Kunzhi Zhang, Haiyang Hu, Geng Wu, Weiwei Wang, Xiongyu Zhu, Gongquan Liu, Ping Xu   +7 more
doaj   +1 more source

Characterization of Argonaute nucleases from mesophilic bacteria Paenibacillus borealis and Brevibacillus laterosporus

Bioresources and Bioprocessing, 2021
Thermophilic Argonaute proteins (Agos) have been shown to utilize small DNA guides for cleaving complementary DNA in vitro, which shows great potential for nucleic acid detection.
Huarong Dong, Fei Huang, Xiang Guo, Xiaoyi Xu, Qian Liu, Xiao Li, Yan Feng   +6 more
doaj   +1 more source

Microbial metabolic noise

WIREs Mechanisms of Disease, 2020
AbstractFrom the time a cell was first placed under the microscope, it became apparent that identifying two clonal cells that “look” identical is extremely challenging. Since then, cell‐to‐cell differences in shape, size, and protein content have been carefully examined, informing us of the ultimate limits that hinder two cells from occupying an ...
Andreas E. Vasdekis, Abhyudai Singh
openaire   +3 more sources

Gut microbiota markers in obese adolescent and adult patients: Age-dependent differential patterns [PDF]

, 2018
Obesity levels, especially in children, have dramatically increased over the last few decades. Recently, several studies highlighted the involvement of gut microbiota in the pathophysiology of obesity. We investigated the composition of gut microbiota in
Alessandra Russo, Andrea Quagliariello, Bruno Dallapiccola, Danila Capoccia, Federica Del Chierico, Francesca Abbatini, Francesco De Peppo, Frida Leonetti, Gianfranco Silecchia, Lorenza Putignani, Lorenza Putignani, Romina Caccamo, Sofia Reddel, Stefano Ginanni Corradini, Valerio Nobili, Valerio Nobili   +15 more
core   +5 more sources