Results 11 to 20 of about 1,423,870 (260)

Microbial Medicine Industry: Current Status and Future Trends

中国工程科学, 2021
The microbial sourced natural products possess diverse structures and excellent activities, implying great potentials for clinical application. This study systematically analyzes the current status of the microbial medicine industry in China and ...
Yu Qing, Huang Tingting, Deng Zixin
doaj   +1 more source

New genomic insights into “Entotheonella” symbionts in Theonella swinhoei: mixotrophy, anaerobic adaptation, resilience, and interaction

Frontiers in Microbiology, 2016
Entotheonella (phylum Tectomicrobia) is a filamentous symbiont that produces almost all known bioactive compounds derived from the Lithistida sponge Theonella swinhoei.
Fang Liu, Jinlong Li, Guofang Feng, Zhiyong Li   +3 more
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The Streptomyces viridochromogenes product template domain represents an evolutionary intermediate between dehydratase and aldol cyclase of type I polyketide synthases

Communications Biology, 2022
Structural analyses of a Streptomyces viridochromogenes product template (PT) domain suggests molecular and functional similarities with known fungal PTs involved in polyketide synthase activity.
Yuanyuan Feng, Xu Yang, Huining Ji, Zixin Deng, Shuangjun Lin, Jianting Zheng   +5 more
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Microbial community development in a dynamic gut model is reproducible, colon region specific, and selective for Bacteroidetes and Clostridium cluster IX [PDF]

, 2010
Dynamic, multicompartment in vitro gastrointestinal simulators are often used to monitor gut microbial dynamics and activity. These reactors need to harbor a microbial community that is stable upon inoculation, colon region specific, and relevant to in ...
Marzorati, M., Sam Possemiers, Sahar El Aidy, Kleerebezem, M., Verstraete, Willy, Smidt, H., Marzorati, Massimo, Philippe Gérard, Rabot, S., Charlotte Grootaert, Verstraete, W., Aidy, S.F., El, Erwin Zoetendal, Hauke Smidt, Possemiers, Sam, Zoetendal, Erwin, Kleerebezem, Michiel, van der Wiele, T., Sylvie Rabot, Grootaert, C., Michiel Kleerebezem, Possemiers, S., Massimo Marzorati, Derrien, Muriel, Pieter Van den Abbeele, Tom Van de Wiele, Derrien, M.M.N., Rabot, Sylvie, Grootaert, Charlotte, van den Abbeele, P., Bruneau, A., Wiele, T., van der, Willy Verstraete, Zoetendal, E.G., El Aidy, Sahar, Gerard, Philippe, Abbeele, P., van den, Muriel Derrien, Smidt, Hauke, Van de Wiele, Tom, Gérard, P., Van den Abbeele, Pieter, Bruneau, Aurelia, El Aidy, S.F., Aurélia Bruneau   +44 more
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The environment within: how gut microbiota may influence metabolism and body composition [PDF]

, 2010
Obesity, diabetes and consequently atherosclerotic vascular disease have become major health and public health issues worldwide. The increasing and staggering prevalence of obesity might not only be explained by nutritional habits or the reduction of ...
Vos, W.M., de, A. Vrieze, Hoekstra, J. B. L., E. G. Zoetendal, Zoetendal, E.G., F. Holleman, Vrieze, A., W. M. de Vos, J. B. L. Hoekstra, M. Nieuwdorp, Holleman, F., Zoetendal, E. G., Hoekstra, J.B., de Vos, W. M., de Vos, W.M., Nieuwdorp, M.   +15 more
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A severe leakage of intermediates to shunt products in acarbose biosynthesis

Nature Communications, 2020
Biosynthetic mechanism for the type 2 diabetes treatment drug acarbose is not fully revealed. Here, the authors show that shunt pathways and inefficient amino-deoxyhexose biosynthesis lead to 1-epi-valienol and valienol accumulation, and minimizing the ...
Qinqin Zhao, Yuchang Luo, Xin Zhang, Qianjin Kang, Dan Zhang, Lili Zhang, Linquan Bai, Zixin Deng   +7 more
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Saccharomyces cerevisiae Culture’s Dose–Response Effects on Ruminal Nutrient Digestibility and Microbial Community: An In Vitro Study

, 2023
Supplementation with saccharomyces cerevisiae culture products (SCs) has shown effectiveness in alleviating or improving the health and productivity of ruminants at a high risk of digestive and metabolic problems as a consequence of their physiological ...
Yanfang Liu, Shengli Li, Fanlin Kong, Cheng Guo, Chunxiao Dong, Xiaofeng Xu, Dongwen Dai, Wei Wang   +7 more
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The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice

BMC Biology, 2021
Background Calorie restriction (CR) and intermittent fasting (IF) can promote metabolic health through a process that is partially mediated by gut microbiota modulation.
Ziyi Zhang, Xiaoyu Chen, Yuh Jiun Loh, Xin Yang, Chenhong Zhang   +4 more
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Mesophilic Argonaute-based isothermal detection of SARS-CoV-2

Frontiers in Microbiology, 2022
Coronavirus disease (COVID-19), caused by SARS-CoV-2 infection and its mutations, has spread rapidly all over the world and still requires sensitive detection to distinguish mutations.
Xiao Li, Huarong Dong, Xiang Guo, Fei Huang, Xiaoyi Xu, Nuolan Li, Yu Yang, Tianbao Yao, Yan Feng, Qian Liu   +9 more
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Seasonal variation and interaction of photodegradation and microbial metabolism of DOC in black water Amazonian ecosystems [PDF]

, 2013
Photodegradation of dissolved organic carbon (DOC) can generate labile substrates readily available for microbial consumption, thus increasing DOC removal, especially in fresh - water humic ecosystems.
Amaral, João Henrique Fernandes, Farjalla, Vinícius Fortes, Suhett, Albert Luiz, Melo, Sérgio   +3 more
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