Results 11 to 20 of about 183,249 (254)

The 24th Annual Midwest Microbial Pathogenesis Meeting. [PDF]

open access: yesJ Bacteriol, 2018
The 24th Annual Midwest Microbial Pathogenesis Conference (MMPC) was held at the University of Notre Dame from 25 to 27 August 2017. The conference provided an opportunity for scientists from the Midwest to discuss new advances in microbial pathogenesis,
Champion PA, Shrout JD.
europepmc   +2 more sources

The role of transcriptional 'futile cycles' in autophagy and microbial pathogenesis. [PDF]

open access: yesMicrob Cell, 2015
Eukaryotic cells utilize macroautophagy (hereafter autophagy) to recycle cellular materials during nutrient stress. Target of rapamycin (Tor) is a central regulator of this process, acting by post-translational mechanisms, phosphorylating ...
Hu G   +13 more
europepmc   +2 more sources

Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy

open access: yesnpj Vaccines, 2023
Staphylococcus aureus infections are a major public health issue, and a vaccine is urgently needed. Despite a considerable promise in preclinical models, all vaccines tested thus far have failed to protect humans against S. aureus. Unlike laboratory mice,
Omid Teymournejad   +4 more
doaj   +1 more source

Microbial pathogenesis and type III interferons [PDF]

open access: yesCytokine and Growth Factor Reviews, 2016
Taylor S Cohen, Dane Parker
exaly   +2 more sources

Control of CD4+ T cells to restrain inflammatory diseases via eukaryotic elongation factor 2 kinase

open access: yesSignal Transduction and Targeted Therapy, 2023
CD4+ T cells, particularly IL-17-secreting helper CD4+ T cells, play a central role in the inflammatory processes underlying autoimmune disorders. Eukaryotic Elongation Factor 2 Kinase (eEF2K) is pivotal in CD8+ T cells and has important implications in ...
Hao-Yun Peng   +9 more
doaj   +1 more source

The Clonal Expansion Dynamics of the HIV-1 Reservoir: Mechanisms of Integration Site-Dependent Proliferation and HIV-1 Persistence

open access: yesViruses, 2021
More than 50% of the HIV-1 latent reservoir is maintained by clonal expansion. The clonally expanded HIV-1-infected cells can contribute to persistent nonsuppressible low-level viremia and viral rebound.
Yang-Hui Jimmy Yeh   +3 more
doaj   +1 more source

Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma

open access: yesMicroorganisms, 2020
Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto   +3 more
doaj   +1 more source

Genomic and Functional Characterization of Longitudinal Pseudomonas aeruginosa Isolates from Young Patients with Cystic Fibrosis

open access: yesMicrobiology Spectrum, 2023
Individuals with cystic fibrosis (CF) suffer from frequent and recurring microbial airway infections. The Gram-negative bacterium Pseudomonas aeruginosa is one of the most common organisms isolated from CF patient airways. P.
Courtney E. Chandler   +4 more
doaj   +1 more source

Editorial: Special issue: Advances in microbial pathogenesis

open access: yes, 2023
Peer ...
Talebi Bezmin Abadi, Amin   +2 more
core   +1 more source

Host Protease Activity on Bacterial Pathogens Promotes Complement and Antibiotic-Directed Killing

open access: yesPathogens, 2021
Our understanding of how the host immune system thwarts bacterial evasive mechanisms remains incomplete. Here, we show that host protease neutrophil elastase acts on Acinetobacter baumannii and Pseudomonas aeruginosa to destroy factors that prevent serum-
Shaorong Chen   +6 more
doaj   +1 more source

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