Results 11 to 20 of about 174,422 (248)

Nudix proteins affecting microbial pathogenesis

open access: yesMicrobiology (United Kingdom), 2020
Nudix proteins catalyse hydrolysis of pyrophosphate bonds in a variety of substrates and are ubiquitous in all domains of life. Their widespread presence and broad substrate specificity suggest that they have important cellular functions. In this review, we summarize the state of knowledge on microbial Nudix proteins involved in pathogenesis.
Elżbieta Kraszewska   +1 more
exaly   +3 more sources

Copper in Microbial Pathogenesis: Meddling with the Metal [PDF]

open access: yesCell Host and Microbe, 2012
Transition metals such as iron, zinc, copper, and manganese are essential for the growth and development of organisms ranging from bacteria to mammals. Numerous studies have focused on the impact of iron availability during bacterial and fungal infections, and increasing evidence suggests that copper is also involved in microbial pathogenesis. Not only
Dennis J Thiele   +2 more
exaly   +3 more sources

Skeletal infections: microbial pathogenesis, immunity and clinical management [PDF]

open access: yesNature Reviews Microbiology, 2022
Gowrishankar Muthukrishnan   +2 more
exaly   +2 more sources

A fine-tuned yeast surface-display/secretion platform enables the rapid discovery of neutralizing antibodies against Clostridioides difficile toxins

open access: yesMicrobial Cell Factories, 2023
Background Neutralizing antibody plays a key role in protecting hosts from invasive pathogens and their virulent components. Current high-throughput assays for antibody screening are based on binding activities.
Ying Sun   +6 more
doaj   +1 more source

Pathogenesis of microbial keratitis [PDF]

open access: yesMicrobial Pathogenesis, 2017
Microbial keratitis is a sight-threatening ocular infection caused by bacteria, fungi, and protist pathogens. Epithelial defects and injuries are key predisposing factors making the eye susceptible to corneal pathogens. Among bacterial pathogens, the most common agents responsible for keratitis include Staphylococcus aureus, Pseudomonas aeruginosa ...
Lakhundi, Sahreena   +2 more
openaire   +2 more sources

A Common Pathway for Activation of Host-Targeting and Bacteria-Targeting Toxins in Human Intestinal Bacteria

open access: yesmBio, 2021
Human gut microbes exhibit a spectrum of cooperative and antagonistic interactions with their host and also with other microbes. The major Bacteroides host-targeting virulence factor, Bacteroides fragilis toxin (BFT), is produced as an inactive protoxin ...
Yiqiao Bao   +6 more
doaj   +1 more source

Nontypeable Haemophilus influenzae released from biofilm residence by monoclonal antibody directed against a biofilm matrix component display a vulnerable phenotype

open access: yesScientific Reports, 2023
Bacterial biofilms contribute significantly to pathogenesis, recurrence and/or chronicity of the majority of bacterial diseases due to their notable recalcitrance to clearance.
Kathryn Q. Wilbanks   +5 more
doaj   +1 more source

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