Results 21 to 30 of about 183,249 (254)

Genetic dysbiosis: the role of microbial insults in chronic inflammatory diseases [PDF]

open access: yes, 2014
Thousands of bacterial phylotypes colonise the human body and the host response to this bacterial challenge greatly influences our state of health or disease. The concept of infectogenomics highlights the importance of host genetic factors in determining
Syed Tariq Sadiq   +7 more
core   +1 more source

Synergetic action between the rumen microbiota and bovine health [PDF]

open access: yes, 2018
Host-rumen-microbe interactions are essential components of many physiological processes, and therefore can affect ruminant health. Classical knowledge of rumen microbiology is based on culture-dependent methodologies, which only account for 10–20% of ...
Zeineldin, Mohamed   +5 more
core   +1 more source

Alternate subunit assembly diversifies the function of a bacterial toxin

open access: yesNature Communications, 2019
Salmonella Typhi produces the typhoid toxin. Here, Fowler et al. show that S. Typhi produces two forms of typhoid toxin that are differentially regulated and display different trafficking properties and different effects when administered to laboratory ...
Casey C. Fowler   +4 more
doaj   +1 more source

Multi-criterion analysis of the effect of physico-chemical microbiological agents on Legionella detection in hotel water distribution systems in Crete

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionWater distribution systems in hotels have been related to outbreaks caused by Legionella spp. Certain measures, including disinfection by chlorination, maintaining increased temperatures are usually undertaken to prevent Legionella outbreaks.
Dimosthenis Chochlakis   +10 more
doaj   +1 more source

De Novo Isolation & Affinity Maturation of yeast-displayed Virion-binding human fibronectin domains by flow cytometric screening against Virions

open access: yesJournal of Biological Engineering, 2019
Background The promise of biopharmaceuticals comprising one or more binding domains motivates the development of novel methods for de novo isolation and affinity maturation of virion-binding domains.
Pete Heinzelman   +4 more
doaj   +1 more source

T Cell Response to SARS-CoV-2 Coinfection and Comorbidities

open access: yesPathogens, 2023
For the past three years, COVID-19 has become an increasing global health issue. Adaptive immune cells, especially T cells, have been extensively investigated in regard to SARS-CoV-2 infection. However, human health and T cell responses are also impacted
Liqing Wang   +8 more
doaj   +1 more source

Syntaxin 11 Contributes to the Interferon-Inducible Restriction of Coxiella burnetii Intracellular Infection

open access: yesmBio, 2023
There is a limited understanding of host defense mechanisms targeting intracellular pathogens that proliferate in a lysosome. Coxiella burnetii is a model bacterial pathogen capable of replicating in the hydrolytic and acidic environment of the lysosome.
Sandhya Ganesan   +5 more
doaj   +1 more source

The frequency, antifungal susceptibility and enzymatic profiles of Candida species in cases of onychomycosis infection

open access: yes, 2021
Although the frequency of candidal onychomycosis is increasing daily, there is little information in literature about the epidemiology, pathogenesis, and antifungal susceptibility of this dermatological disease.
Sav, Hafize   +4 more
core   +1 more source

Novel Components of the Flagellar System in Epsilonproteobacteria

open access: yesmBio, 2014
Motility is essential for the pathogenesis of many bacterial species. Most bacteria move using flagella, which are multiprotein filaments that rotate propelled by a cell wall-anchored motor using chemical energy. Although some components of the flagellar
Beile Gao   +4 more
doaj   +1 more source

Stabilization of Tuberculosis Reporter Enzyme Fluorescence (REFtb) Diagnostic Reagents for Use at the Point of Care

open access: yesDiagnostics, 2022
Tuberculosis is one of the most frequent causes of death in humans worldwide. One of the primary reasons tuberculosis remains a public health threat is that diagnosis can take weeks to months, is often not very sensitive and cannot be accomplished in ...
Maxim Lebedev   +6 more
doaj   +1 more source

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